Oak Longevity vs SkinnyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent researchHow we rank →

Oak Longevity beats SkinnyRx overall, scoring 7.5/10 vs 7.3/10. Oak Longevity is more affordable at $133/mo vs $199/mo. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo.

A side-by-side look at Oak Longevity and SkinnyRx to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Oak Longevity

#25 of 53
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing, patients pay each month manually rather than auto-renew.

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SkinnyRx

#35 of 53
7.3/10

Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats, injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only, does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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FeatureOak LongevitySkinnyRx
Our Score7.5/107.3/10
Starting Price$133/mo$199/mo
Medication TypeBothCompounded
Insurance AcceptedNoNo
Best ForBudget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin)Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point
Watch out forBrand-name pricing ($1,200-$1,500/mo) is significantly above market, NovoCare sells Wegovy direct at $349/mo and LillyDirect has Zepbound at $299/mo. Use Oak for its compounded tiers and buy brand-name directNo brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
Ranking#25#35
Get startedVisit Oak LongevityVisit SkinnyRx

Pros & Cons Compared

Oak Longevity

Pros

  • +$133/mo for compounded semaglutide is among the cheapest entries on the market, Sesame Care ($99) is lower, but Oak undercuts most mid-tier platforms
  • +No-subscription model, patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
  • +Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
  • +Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
  • +Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Brand-name pricing ($1,200-$1,500/mo) is significantly above market, NovoCare sells Wegovy direct at $349/mo and LillyDirect has Zepbound at $299/mo. Use Oak for its compounded tiers and buy brand-name direct
  • No published lab panels and no specialty (obesity medicine) physicians disclosed, clinical oversight is lighter than lab-driven platforms
  • The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
  • The longevity add-ons (NAD+, Sermorelin, Tesamorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
  • Newer brand without disclosed company history, founding date, or executive team on landing pages
  • Three-month plans are billed upfront, start on the 1-month plan if you're testing the platform, then bundle once it fits

SkinnyRx

Pros

  • +Five medication formats, the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
  • +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
  • +Fast onboarding: 5-10 minute online questionnaire, physician review in 24-48 hours, medication delivered in 3-7 business days with temperature-controlled shipping
  • +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

  • No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
  • Light public disclosure: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site, ask support before enrolling if provenance matters to you
  • Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
  • Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat

Our Verdict

Oak Longevity edges out SkinnyRx with a score of 7.5/10 vs 7.3/10. If budget is your priority, Oak Longevity starts at $133/mo compared to SkinnyRx's $199/mo. Oak Longevity offers both brand-name and compounded medications, giving you more flexibility. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin). Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point.

Try Oak Longevity

Starting at $133/mo

Visit Oak Longevity

Try SkinnyRx

Starting at $199/mo

Visit SkinnyRx

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