Oak Longevity vs SkinnyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

Short answer: Oak Longevity scores higher on our rubric, 7.5/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Oak Longevity beats SkinnyRx overall, scoring 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Oak Longevity is from $167/mo; SkinnyRx is $99 first month, rises after. Choose Oak Longevity for budget-conscious users who want one of the cheapest compounded glp-1 entries, a flat price across every dose, and a longevity-stack add-on (nad+, glutathione, sermorelin). Choose SkinnyRx for users who want a choice of compounded glp-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price.

A side-by-side look at Oak Longevity and SkinnyRx to help you decide. We compare them on:

  • Starting price and billing period
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Oak Longevity

#11 of 36
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, across injectable and non-injectable routes, alongside a longevity stack (NAD+, Glutathione, Sermorelin). Every dose is priced the same, so titrating up does not raise the monthly cost. Plans run as a subscription that renews automatically and can be cancelled from the account at any time.

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SkinnyRx

#28 of 36
5.3/10

Direct-to-consumer telehealth platform operated by Lean Rx, Inc. (Sacramento, CA). Its Treatments menu carries four compounded GLP-1 formats, semaglutide and tirzepatide each as a once-weekly injection or a once-daily tablet taken under the tongue, plus two brand-name oral pills, the Wegovy Pill and the Foundayo Pill, both badged FDA-approved and both shown as Unavailable and offered through a SkinnyRx Membership. Every advertised price is a first month rate. Compounded medications are not sold in Alabama, Louisiana or Mississippi. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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FeatureOak LongevitySkinnyRx
Why each oneOne price per medication regardless of dose, so titrating up does not raise the bill. Combined with three compounded routes and a longevity peptide menu, Oak reads as a 'menu' platform rather than the typical single-product flow.
Both GLP-1 molecules in both administration routes: semaglutide and tirzepatide, each as a once-weekly injection or a once-daily tablet taken under the tongue. The tirzepatide tablet in particular is a format almost no other DTC platform offers, and the two brand-name oral pills it lists alongside them are currently shown as Unavailable.
Our Score7.5/105.3/10
Headline Pricefrom $167/mo$99 first month, rises after
Medication TypeCompoundedBoth
Insurance AcceptedNoNo
Best ForBudget-conscious users who want one of the cheapest compounded GLP-1 entries, a flat price across every dose, and a longevity-stack add-on (NAD+, Glutathione, Sermorelin)
Users who want a choice of compounded GLP-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price
Watch out forCompounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
Ranking#11#28
Get startedVisit Oak LongevityVisit SkinnyRx

Pros & Cons Compared

Oak Longevity

Pros

  • +A $167/mo starting price on its compounded semaglutide page, with no membership fee, free shipping and free health coaching included
  • +Every dose costs the same, so moving to a higher dose during titration does not raise the monthly bill, stated on the product page and in the blog
  • +Three compounded routes including a non-injectable oral or sublingual option, unusual at this price
  • +Longevity peptides (NAD+, Glutathione, Sermorelin) sit alongside the GLP-1 menu on one platform
  • +Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
  • Obesity-certified doctors are advertised on the weight loss page, but no clinician roster or credentials are published, and no lab panels or blood work are offered anywhere on the site (rendered check 2026-09-03)
  • The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
  • The longevity add-ons it lists (NAD+, Glutathione, Sermorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
  • The operating entity appears only in the footer and legal pages, as Leaf Longevity Holdings Corp trading as Oak Longevity, and no founding date, named leadership, about page or team page exists on the site (rendered check 2026-09-03)
  • Its published starting price is not consistent: $119 a month in the homepage FAQ, $167 on the compounded semaglutide page, $180 in its own blog and $190 on the weight loss page, so settle the figure at checkout before you commit

SkinnyRx

Pros

  • +Four compounded formats, both molecules as both a weekly injection and a daily tablet taken under the tongue, including the tirzepatide tablet that almost no competitor offers
  • +$99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
  • +Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
  • +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

  • Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
  • SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
  • Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
  • Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
  • FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding

Our Verdict

Oak Longevity edges out SkinnyRx with a score of 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Oak Longevity is from $167/mo; SkinnyRx is $99 first month, rises after. SkinnyRx offers both brand-name and compounded medications, giving you more flexibility.

Try Oak Longevity

Headline price: from $167/mo

Visit Oak Longevity

Try SkinnyRx

Headline price: $99 first month, rises after

Visit SkinnyRx

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