Novi vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent research·How we rank →

Visit TMates - our pick of these two→or find your match

Novi and TMates are tied at 7.8/10. Novi is more affordable at $133/mo vs $158/mo. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa. Choose TMates for users who want commitment-discount pricing on compounded glp.

A side-by-side look at Novi and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Novi

#12 of 53

7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing, medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

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TMates

#14 of 53

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

Visit TMates

Feature	Novi	TMates
Our Score	7.8/10	7.8/10
Starting Price	$133/mo	$158/mo
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out for	Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
Ranking	#12	#14
Get started	Visit Novi	Visit TMates

Pros & Cons Compared

Novi

Pros

+Six disclosed clinicians on staff, Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP), more named providers than most compounded-only platforms publish
+Month-to-month billing with no minimum commitment, cancel before any renewal date with no early-termination penalty
+Aggressive promotional pricing on the offer landing, $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
+Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
+Free 2-day shipping; same active ingredients as Wegovy/Ozempic and Mounjaro/Zepbound (semaglutide and tirzepatide respectively)
+100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
−Founding year, headquarters city, and corporate ownership are not publicly disclosed
−Promotional $99-$133 pricing applies to the introductory offer landing only, standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
−Once medication is dispensed/shipped, prescriptions cannot be returned or refunded, typical for compounded telehealth but worth understanding
−Lab requirements before prescribing are not disclosed on public pages, unclear whether baseline bloodwork is required
−Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

Novi and TMates are closely matched with identical scores of 7.8/10. If budget is your priority, Novi starts at $133/mo compared to TMates's $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer. Choose TMates if you want: users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Novi nor TMates feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Visit TrimRx→Read our full TrimRx review