Visit TMatesResearched against FDA labeling, published clinical-trial data (STEP-1 / SURMOUNT-1), and TMates's live pages, not a paid placement.

TMates GLP-1 Review
Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.
TMates gives you two distinct ways to buy: all-in compounded GLP-1s at $158/mo on the 12-month plan (or $249 month-to-month), and a $99/mo clinical service for brand Wegovy/Zepbound where your own pharmacy dispenses the drug. Full verdict ↓
Clinical evidence: 20.9% average body-weight reduction at 72 weeks in SURMOUNT-1 (NEJM, 2022). Individual results vary; compounded GLP-1s are not FDA-approved.
Summarize this article with
TMates scores 7.8/10 in our independent review, starting at $158/mo for brand-name and compounded GLP-1 medications. TMates is one of the few platforms with a cheap clinical path to brand-name GLP-1s: $99/mo for the Wegovy or Zepbound prescription, medication billed separately at your pharmacy (ideal when insurance covers the drug). Compounded semaglutide and tirzepatide are all-in with medication and free shipping: $249/mo month-to-month, down to $158/mo on the 12-month plan.
What makes it different: Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
At a glance
- Patients who want commitment pricing on compounded GLP-1s, or those with insurance who want a cheap telemedicine path ($99/mo) to a brand Wegovy or Zepbound prescription they fill at their own pharmacy.
- Patients who expect the $99/mo Wegovy/Zepbound tier to include medication (it does not, that's prescription service only) or who want thorough medical oversight (90-second intake is light).
TMates Pros and Cons
What We Like
- +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
- +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
- +Same price at all dose levels for compounded, no cost escalation as you titrate up
- +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach
What Could Be Better
- −The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
- −The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
- −The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
- −TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.
What it costs
Headline pricing, full-year math, and how TMates compares to the closest alternatives.
Quick facts
All pricing tiers
Compounded Semaglutide (month-to-month)
$249/mo$249/mo month-to-month with medication and free shipping included, all doses at same price
Compounded Semaglutide (3-month plan)
$217/mo$217/mo on 3-month commitment ($650 upfront, save 13%)
Compounded Semaglutide (6-month plan)
$175/mo$175/mo on 6-month commitment ($1,050 upfront, save 30%)
Compounded Semaglutide (12-month plan)
$158/mo$158/mo on 12-month commitment ($1,900 upfront, save 37%), lowest effective rate
Compounded Tirzepatide (starting)
$167/moFrom $167/mo, multi-month commitment discounts similar to sema structure
Phentermine (oral)
$149/mo$149/mo, non-GLP-1 appetite suppressant option
Wegovy (brand clinical service only)
$99/mo$99/mo for the prescription + provider oversight. Medication cost is separate, you fill the Rx at your own pharmacy.
Zepbound (brand clinical service only)
$99/mo$99/mo for the prescription + provider oversight. Medication cost is separate, you fill the Rx at your own pharmacy.
Cancellation policy: 100% refund available, contact support, no questions asked
What third-party review aggregators say about TMates. Cards show the verified primary metric only, “Not found” means no public profile surfaced in our verification pass.
TMates has a near-nonexistent independent review footprint. Its real Trustpilot profile shows a TrustScore of just 3.2 from a single review (a 1-star review citing a $347 charge, an un-bookable consultation, and only a partial refund), and a secondary Trustpilot profile (tmates.reviewsandbuy.com) was removed by Trustpilot for guideline violations. This directly contradicts the "4.9 stars from 4,700+ reviews" the company displays on its own site. BBB lists it as not accredited with multiple billing and cancellation complaints. Recurring criticism centers on billing disputes, unwanted charges after cancellation, and difficulty scheduling consultations.
Reddit: Essentially zero organic Reddit discussion despite TMates claiming 40,000+ patients; the absence of any community footprint is itself a red flag, and the limited third-party reviews that exist skew negative (billing and cancellation friction).
90-Second Assessment
Complete a quick quiz covering medical history, medications, previous weight loss attempts, and goals.
Provider Review & Recommendation
A licensed provider reviews your information and recommends the appropriate GLP-1 treatment plan.
Medication Ships with Full Support
If approved, compounded medication ships with health coaching, nutrition guidance, progress tracking, and 24/7 support access. For brand-name, the prescription is sent to your pharmacy.
Medications available
Ready to check TMates's pricing for yourself?
Visit TMatesSix trust signals, how we checked them, and what's been updated since the last review.
What the doctors say about GLP-1 medications
Independent, sourced clinical context on the medication class, not a comment on this provider.
“People with overweight or obesity have individual preferences, and with oral semaglutide as a potential new treatment option, more of those who are not on treatment today may consider starting GLP-1 treatment.”
“We now have medicines that not only reduce heart attacks, strokes, and peripheral arterial disease, but also simultaneously lead to meaningful weight loss – which in turn lowers the risk of many weight-related conditions. These treatments also improve patients' quality of life in a meaningful way, making this a genuine win–win.”
Quotes are general medical commentary about GLP-1 medications, independently sourced and not solicited by GLP-1 Picks. They are not an endorsement of any provider, our provider scores are set solely by our published methodology.
Common questions
Questions readers ask about TMates, similar providers to compare, and quick tools.
Frequently Asked Questions
Does the $99/mo Wegovy or Zepbound include medication?+
Does TMates accept my insurance?+
What are the multi-month discounts?+
Is phentermine available?+
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