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Our Score
7.8/10
TypeBoth
InsuranceYes
Rank#14 of 52
Brand-nameCompoundedInsurance AcceptedUpdated May 17, 2026
By Iacob Pastina, Independent Editor & Researcher
Reviewed & updated May 17, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

Researched against FDA labeling, published clinical-trial data (STEP-1 / SURMOUNT-1), and TMates's live pages, not a paid placement.

TMates logo

TMates GLP-1 Review

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

Bottom line

TMates gives you two distinct ways to buy: all-in compounded GLP-1s at $158/mo on the 12-month plan (or $249 month-to-month), and a $99/mo clinical service for brand Wegovy/Zepbound where your own pharmacy dispenses the drug. Full verdict ↓

Independently researched. Every statistic links to a primary source (NEJM, JAMA, FDA, CMS, or the provider's official disclosures). Affiliate status never changes a provider's score; featured picks are affiliate partners, disclosed. Last verified May 17, 2026.

Clinical evidence: 20.9% average body-weight reduction at 72 weeks in SURMOUNT-1 (NEJM, 2022). Individual results vary; compounded GLP-1s are not FDA-approved.

Summarize this article with

TMates scores 7.8/10 in our independent review, starting at $158/mo for brand-name and compounded GLP-1 medications. TMates is one of the few platforms with a cheap clinical path to brand-name GLP-1s: $99/mo for the Wegovy or Zepbound prescription, medication billed separately at your pharmacy (ideal when insurance covers the drug). Compounded semaglutide and tirzepatide are all-in with medication and free shipping: $249/mo month-to-month, down to $158/mo on the 12-month plan.

What makes it different: Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.

At a glance

Get TMates if
  • Patients who want commitment pricing on compounded GLP-1s, or those with insurance who want a cheap telemedicine path ($99/mo) to a brand Wegovy or Zepbound prescription they fill at their own pharmacy.
Skip if
  • Patients who expect the $99/mo Wegovy/Zepbound tier to include medication (it does not, that's prescription service only) or who want thorough medical oversight (90-second intake is light).

TMates Pros and Cons

What We Like

  • +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
  • +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
  • +Same price at all dose levels for compounded, no cost escalation as you titrate up
  • +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

What Could Be Better

  • The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
  • The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
  • The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
  • TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

What it costs

Headline pricing, full-year math, and how TMates compares to the closest alternatives.

Quick facts

Monthly Cost
Consultation
Included
Availability
All 50 states + Puerto Rico
Insurance
Accepted
Shipping
Free
Cancellation
100% refund available, conta...

All pricing tiers

Compounded Semaglutide (month-to-month)

$249/mo

$249/mo month-to-month with medication and free shipping included, all doses at same price

Compounded Semaglutide (3-month plan)

$217/mo

$217/mo on 3-month commitment ($650 upfront, save 13%)

Compounded Semaglutide (6-month plan)

$175/mo

$175/mo on 6-month commitment ($1,050 upfront, save 30%)

Compounded Semaglutide (12-month plan)

$158/mo

$158/mo on 12-month commitment ($1,900 upfront, save 37%), lowest effective rate

Compounded Tirzepatide (starting)

$167/mo

From $167/mo, multi-month commitment discounts similar to sema structure

Phentermine (oral)

$149/mo

$149/mo, non-GLP-1 appetite suppressant option

Wegovy (brand clinical service only)

$99/mo

$99/mo for the prescription + provider oversight. Medication cost is separate, you fill the Rx at your own pharmacy.

Zepbound (brand clinical service only)

$99/mo

$99/mo for the prescription + provider oversight. Medication cost is separate, you fill the Rx at your own pharmacy.

Cancellation policy: 100% refund available, contact support, no questions asked

Ready to check TMates's pricing for yourself?

Visit TMates

Common questions

Questions readers ask about TMates, similar providers to compare, and quick tools.

Frequently Asked Questions

Does the $99/mo Wegovy or Zepbound include medication?+
No. The $99/mo covers the clinical service only: TMates provides the prescription and provider oversight, and you fill the Rx at your preferred pharmacy, where insurance may cover the medication cost. If you want medication included in one price, use the compounded plans instead.
Does TMates accept my insurance?+
TMates works with Aetna, Cigna, UnitedHealthcare, and Blue Cross Blue Shield for medical evaluation. For brand-name medications filled at your pharmacy, your insurance may also cover the drug cost, TMates does not bill insurance for the drug itself.
What are the multi-month discounts?+
Compounded semaglutide: $249/mo month-to-month, $217/mo (3-mo, $650 upfront), $175/mo (6-mo, $1,050 upfront), $158/mo (12-mo, $1,900 upfront). Save up to 37% on the longest plan.
Is phentermine available?+
Yes. Phentermine at $149/mo is available as a non-GLP-1 appetite suppressant option for patients who may benefit from a different approach.

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.