By Iacob Pastina · Independent Editor
TMates GLP-1 Review
Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.
Summarize this article with
TMates scores 7.8/10 in our independent review, starting at $158/mo for brand-name and compounded GLP-1 medications. TMates added brand-name Wegovy and Zepbound access in 2026 via a clinical-service-only model — $99/mo for the prescription, medication billed separately at your pharmacy. Compounded semaglutide and tirzepatide use commitment pricing: $158/mo on 12-month plan or $249/mo month-to-month, medication included with free shipping.
What makes it different: Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
At a glance
- Patients who want commitment pricing on compounded GLP-1s, or those with insurance who want a cheap telemedicine path ($99/mo) to a brand Wegovy or Zepbound prescription they fill at their own pharmacy.
- Patients who expect the $99/mo Wegovy/Zepbound tier to include medication (it does not — that's prescription service only) or who want thorough medical oversight (90-second intake is light).
TMates Pros and Cons
What We Like
- +Steep multi-month commitment discounts on compounded sema — $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
- +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo — prescription goes to patient's pharmacy (you fill separately using insurance or cash)
- +Same price at all dose levels for compounded — no cost escalation as you titrate up
- +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach
What Could Be Better
- −Brand Wegovy/Zepbound $99/mo is CLINICAL SERVICE ONLY — medication cost is separate (paid at your pharmacy, which can be $1,000+/mo cash without insurance)
- −Best compounded pricing requires 6-12 month prepayment (upfront $1,050-$1,900)
- −90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
- −Not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound) — TMates prescribes but does not dispense brand-name
What it costs
Headline pricing, full-year math, and how TMates compares to the closest alternatives.
Quick facts
All pricing tiers
Compounded Semaglutide (month-to-month)
$249/mo$249/mo month-to-month with medication and free shipping included — all doses at same price
Compounded Semaglutide (3-month plan)
$217/mo$217/mo on 3-month commitment ($650 upfront, save 13%)
Compounded Semaglutide (6-month plan)
$175/mo$175/mo on 6-month commitment ($1,050 upfront, save 30%)
Compounded Semaglutide (12-month plan)
$158/mo$158/mo on 12-month commitment ($1,900 upfront, save 37%) — lowest effective rate
Compounded Tirzepatide (starting)
$167/moFrom $167/mo — multi-month commitment discounts similar to sema structure
Phentermine (oral)
$149/mo$149/mo — non-GLP-1 appetite suppressant option
Wegovy (brand clinical service only)
$99/mo$99/mo for the prescription + provider oversight. Medication cost is separate — you fill the Rx at your own pharmacy.
Zepbound (brand clinical service only)
$99/mo$99/mo for the prescription + provider oversight. Medication cost is separate — you fill the Rx at your own pharmacy.
Cancellation policy: 100% refund available — contact support, no questions asked
How TMates works
90-Second Assessment
Complete a quick quiz covering medical history, medications, previous weight loss attempts, and goals.
Provider Review & Recommendation
A licensed provider reviews your information and recommends the appropriate GLP-1 treatment plan.
Medication Ships with Full Support
If approved, compounded medication ships with health coaching, nutrition guidance, progress tracking, and 24/7 support access. For brand-name, the prescription is sent to your pharmacy.
Medications available
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Six trust signals, how we checked them, and what's been updated since the last review.
Common questions
Questions readers ask about TMates, similar providers to compare, and quick tools.
Frequently Asked Questions
Does the $99/mo Wegovy or Zepbound include medication?+
Does TMates accept my insurance?+
What are the multi-month discounts?+
Is phentermine available?+
Alternatives to TMates
Similar providers by type, price, and features
Medicare GLP-1 Bridge Enrollment Guide 2026: $50 Copay for Foundayo, Wegovy & Zepbound
Cost & InsuranceCompounded Semaglutide Ban (2026): FDA Crackdown Explained + 4 Legal Switch Options
ComparisonsIvyRx GLP-1 Review 2026: Flat-Rate Compounded Semaglutide & Tirzepatide at $175–$297/mo
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From $158/mo·7.8/10·compare all 48