Oak Longevity vs TMates: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
TMates beats Oak Longevity overall, scoring 7.8/10 vs 7.5/10. Oak Longevity is more affordable at $130/mo vs $158/mo. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound. Choose TMates for users who want flexible pricing across compounded glp-1s (me.
A side-by-side comparison of Oak Longevity and TMates covering pricing, scores, medication types, insurance, and more to help you decide.
Oak Longevity
#23 of 42Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing — patients pay each month manually rather than auto-renew.
Visit Oak LongevityTMates
#15 of 42Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.
Visit TMates| Feature | Oak Longevity | TMates |
|---|---|---|
| Our Score | 7.5/10 | 7.8/10 |
| Starting Price | $130/mo | $158/mo |
| Medication Type | Both | Both |
| Insurance Accepted | No | Yes |
| Best For | Budget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin) | Users who want flexible pricing across compounded GLP-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand Wegovy or Zepbound ($99/mo, patient fills at own pharmacy) |
| Ranking | #23 | #15 |
Pros & Cons Compared
Oak Longevity
Pros
- +$130/mo for compounded semaglutide is among the cheapest entries on the market — Sprout Health ($99) and Sesame Care ($99) are lower, but Oak undercuts most mid-tier platforms
- +Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
- +No-subscription model — patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
- +Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
- +Money-back guarantee if not approved by physician — useful safety net for borderline-eligibility patients
- +Free shipping and free health coaching included in every program
Cons
- −Brand-name pricing ($1,200-$1,500/mo) is significantly above market — NovoCare direct pricing for Wegovy is $349/mo, LillyDirect Zepbound $299/mo. Never buy brand-name through Oak
- −No published lab panels, no specialty (obesity medicine) physicians disclosed — clinical depth is shallow
- −'Up to 50% cheaper than competitors' marketing claim is unverified and inconsistent — depends on which competitor and which medication tier
- −'Longevity' framing pushes users toward add-on products (NAD+, Sermorelin, Tesamorelin) that have limited clinical evidence for weight loss specifically
- −Newer brand without disclosed company history, founding date, or executive team on landing pages
- −Three-month plans are billed upfront — pricing transparency is good, but commit-up-front is a friction point for users testing the platform
TMates
Pros
- +Steep multi-month commitment discounts on compounded sema — $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
- +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo — prescription goes to patient's pharmacy (you fill separately using insurance or cash)
- +Same price at all dose levels for compounded — no cost escalation as you titrate up
- +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach
Cons
- −Brand Wegovy/Zepbound $99/mo is CLINICAL SERVICE ONLY — medication cost is separate (paid at your pharmacy, which can be $1,000+/mo cash without insurance)
- −Best compounded pricing requires 6-12 month prepayment (upfront $1,050-$1,900)
- −90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
- −Not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound) — TMates prescribes but does not dispense brand-name
Our Verdict
TMates edges out Oak Longevity with a score of 7.8/10 vs 7.5/10. If budget is your priority, Oak Longevity starts at $130/mo compared to TMates's $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin). Choose TMates if you want: users who want flexible pricing across compounded glp-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand wegovy or zepbound ($99/mo, patient fills at own pharmacy).