Oak Longevity vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

TMates beats Oak Longevity overall, scoring 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Oak Longevity is from $167/mo; TMates is from $158/mo. Choose Oak Longevity for budget-conscious users who want one of the cheapest compounded glp-1 entries, a flat price across every dose, and a longevity-stack add-on (nad+, glutathione, sermorelin). Choose TMates for users who want commitment-discount pricing on compounded glp-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

A side-by-side look at Oak Longevity and TMates to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

Oak Longevity

#18 of 54
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, across injectable and non-injectable routes, alongside a longevity stack (NAD+, Glutathione, Sermorelin). Every dose is priced the same, so titrating up does not raise the monthly cost. Plans run as a subscription that renews automatically and can be cancelled from the account at any time.

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Higher Rated

TMates

#10 of 54
7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (semaglutide $158-$249/mo, tirzepatide $167-$297/mo on commitment pricing), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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FeatureOak LongevityTMates
Why each oneOne price per medication regardless of dose, so titrating up does not raise the bill. Combined with three compounded routes and a longevity peptide menu, Oak reads as a 'menu' platform rather than the typical single-product flow.
Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
Our Score7.5/107.8/10
Headline Pricefrom $167/mofrom $158/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoYes
Best ForBudget-conscious users who want one of the cheapest compounded GLP-1 entries, a flat price across every dose, and a longevity-stack add-on (NAD+, Glutathione, Sermorelin)
Users who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out forCompounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
Ranking#18#10
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Pros & Cons Compared

Oak Longevity

Pros

  • +A $167/mo starting price on its compounded semaglutide page, with no membership fee, free shipping and free health coaching included
  • +Every dose costs the same, so moving to a higher dose during titration does not raise the monthly bill, stated on the product page and in the blog
  • +Three compounded routes including a non-injectable oral or sublingual option, unusual at this price
  • +Longevity peptides (NAD+, Glutathione, Sermorelin) sit alongside the GLP-1 menu on one platform
  • +Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
  • Obesity-certified doctors are advertised on the weight loss page, but no clinician roster or credentials are published, and no lab panels or blood work are offered anywhere on the site (rendered check 2026-09-03)
  • The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
  • The longevity add-ons it lists (NAD+, Glutathione, Sermorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
  • The operating entity appears only in the footer and legal pages, as Leaf Longevity Holdings Corp trading as Oak Longevity, and no founding date, named leadership, about page or team page exists on the site (rendered check 2026-09-03)
  • Its published starting price is not consistent: $119 a month in the homepage FAQ, $167 on the compounded semaglutide page, $180 in its own blog and $190 on the weight loss page, so settle the figure at checkout before you commit

TMates

Pros

  • +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
  • +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
  • +Same price at all dose levels for compounded, no cost escalation as you titrate up
  • +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

  • The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
  • The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
  • The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
  • TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out Oak Longevity with a score of 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Oak Longevity is from $167/mo; TMates is from $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both Oak Longevity and TMates start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Try Oak Longevity

Headline price: from $167/mo

Visit Oak Longevity

Try TMates

Headline price: from $158/mo

Visit TMates

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