Calibrate vs Novi: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent research·How we rank →

Visit TrimRx - our featured pick→or find your match

Novi beats Calibrate overall, scoring 7.8/10 vs 7.7/10. Novi is more affordable at $133/mo vs $199/mo. Choose Calibrate for users who want a physician-led metabolic health program with. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa.

A side-by-side look at Calibrate and Novi to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Calibrate

#19 of 53

7.7/10

Metabolic health company offering a physician-led GLP-1 program restructured in 2026: $199/mo with a 3-month minimum commitment (no more $1,649 one-time enrollment fee). Includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.

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Higher Rated

Novi

#12 of 53

7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing, medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

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Feature	Calibrate	Novi
Our Score	7.7/10	7.8/10
Starting Price	$199/mo	$133/mo
Medication Type	Both	Compounded
Insurance Accepted	Yes	No
Best For	Users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee	Cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer
Watch out for	$597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors	Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
Ranking	#19	#12
Get started	Visit Calibrate	Visit Novi

Pros & Cons Compared

Calibrate

Pros

+2026 pricing rewrite, flat $199/mo with 3-month commitment ($597 upfront), then month-to-month. The old $1,649 one-time enrollment fee was removed.
+Board-certified physicians with metabolic health specialization lead treatment
+10%+ body-weight-loss guarantee with 50% money-back if not met
+Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support

Cons

−$597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
−Medication cost is separate and varies significantly by payer route
−Fewer medications in the menu than larger marketplaces like Ro or Found
−Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan

Novi

Pros

+Six disclosed clinicians on staff, Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP), more named providers than most compounded-only platforms publish
+Month-to-month billing with no minimum commitment, cancel before any renewal date with no early-termination penalty
+Aggressive promotional pricing on the offer landing, $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
+Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
+Free 2-day shipping; same active ingredients as Wegovy/Ozempic and Mounjaro/Zepbound (semaglutide and tirzepatide respectively)
+100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
−Founding year, headquarters city, and corporate ownership are not publicly disclosed
−Promotional $99-$133 pricing applies to the introductory offer landing only, standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
−Once medication is dispensed/shipped, prescriptions cannot be returned or refunded, typical for compounded telehealth but worth understanding
−Lab requirements before prescribing are not disclosed on public pages, unclear whether baseline bloodwork is required
−Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

Our Verdict

Novi edges out Calibrate with a score of 7.8/10 vs 7.7/10. If budget is your priority, Novi starts at $133/mo compared to Calibrate's $199/mo. Calibrate accepts insurance, which can significantly reduce your out-of-pocket costs. Calibrate offers both brand-name and compounded medications, giving you more flexibility. Choose Calibrate if you want: users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer.

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Calibrate nor Novi feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Visit TrimRx→Read our full TrimRx review