Calibrate vs Novi: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Novi beats Calibrate overall, scoring 7.8/10 vs 7.7/10. Novi is more affordable at $133/mo vs $199/mo. Choose Calibrate for users who want a physician-led metabolic health program with. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa.

A side-by-side comparison of Calibrate and Novi covering pricing, scores, medication types, insurance, and more to help you decide.

Calibrate

#21 of 46
7.7/10

Metabolic health company offering a physician-led GLP-1 program restructured in 2026: $199/mo with a 3-month minimum commitment (no more $1,649 one-time enrollment fee). Includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.

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Higher Rated

Novi

#14 of 46
7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing — medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

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FeatureCalibrateNovi
Our Score7.7/107.8/10
Starting Price$199/mo$133/mo
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guaranteeCash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer
Ranking#21#14

Pros & Cons Compared

Calibrate

Pros

  • +2026 pricing rewrite — flat $199/mo with 3-month commitment ($597 upfront), then month-to-month. The old $1,649 one-time enrollment fee was removed.
  • +Board-certified physicians with metabolic health specialization lead treatment
  • +10%+ body-weight-loss guarantee with 50% money-back if not met
  • +Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support

Cons

  • $597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
  • Medication cost is separate and varies significantly by payer route
  • Fewer medications in the menu than marketplaces like Sesame Care or Ro
  • Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan

Novi

Pros

  • +Six disclosed clinicians on staff — Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP) — more named providers than most compounded-only platforms publish
  • +Month-to-month billing with no minimum commitment — cancel before any renewal date with no early-termination penalty
  • +Aggressive promotional pricing on the offer landing — $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
  • +Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
  • +Free 2-day shipping; same active ingredients as Wegovy/Ozempic and Mounjaro/Zepbound (semaglutide and tirzepatide respectively)
  • +100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

  • Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
  • Founding year, headquarters city, and corporate ownership are not publicly disclosed
  • Promotional $99-$133 pricing applies to the introductory offer landing only — standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
  • Once medication is dispensed/shipped, prescriptions cannot be returned or refunded — typical for compounded telehealth but worth understanding
  • Lab requirements before prescribing are not disclosed on public pages — unclear whether baseline bloodwork is required
  • Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

Our Verdict

Novi edges out Calibrate with a score of 7.8/10 vs 7.7/10. If budget is your priority, Novi starts at $133/mo compared to Calibrate's $199/mo. Calibrate accepts insurance, which can significantly reduce your out-of-pocket costs. Calibrate offers both brand-name and compounded medications, giving you more flexibility. Choose Calibrate if you want: users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer.

Try Calibrate

Starting at $199/mo

Visit Calibrate

Try Novi

Starting at $133/mo

Visit Novi
Top Picks

Three programs our readers click through most.

Eden Health GLP-1

8.9/10
$249/mo·Brand & Compounded

Sesame Care

7.9/10
$59/mo·Brand & Compounded

Sprout Health

8.8/10
$249/mo·Brand & Compounded

Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

Today's Cheapest

Sesame Care — $59/mo