Direct Meds GLP-1 vs Novi: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent researchHow we rank →

Direct Meds GLP-1 beats Novi overall, scoring 7.9/10 vs 7.8/10. Novi is more affordable at $133/mo vs $297/mo. Choose Direct Meds GLP-1 for users wanting simple, all-inclusive pricing without insuranc. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa.

A side-by-side look at Direct Meds GLP-1 and Novi to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Direct Meds GLP-1

#10 of 53
7.9/10

Straightforward compounded GLP-1 program with transparent all-inclusive pricing and no hidden fees.

Visit Direct Meds GLP-1

Novi

#12 of 53
7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing, medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

Visit Novi
FeatureDirect Meds GLP-1Novi
Our Score7.9/107.8/10
Starting Price$297/mo$133/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers wanting simple, all-inclusive pricing without insuranceCash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer
Watch out forCompounded medications only, no brand-name Wegovy, Zepbound, or Ozempic on the menuCompounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
Ranking#10#12
Get startedVisit Direct Meds GLP-1Visit Novi

Pros & Cons Compared

Direct Meds GLP-1

Pros

  • +True all-inclusive pricing, $280/mo covers medication, consultations, shipping, and pharmacy fees with no add-ons
  • +Clear dose-based pricing published on their site, no surprise cost increases when titrating up
  • +Fast pharmacy fulfillment: most orders ship within 48 hours of provider approval
  • +Responsive customer support with live chat available during business hours

Cons

  • Compounded medications only, no brand-name Wegovy, Zepbound, or Ozempic on the menu
  • The $280/mo flat rate sits above Henry Meds ($199) and TrimRx ($149); Direct Meds' own sublingual drops at $179 are the budget path if the premium stings

Novi

Pros

  • +Six disclosed clinicians on staff, Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP), more named providers than most compounded-only platforms publish
  • +Month-to-month billing with no minimum commitment, cancel before any renewal date with no early-termination penalty
  • +Aggressive promotional pricing on the offer landing, $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
  • +Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
  • +Free 2-day shipping; same active ingredients as Wegovy/Ozempic and Mounjaro/Zepbound (semaglutide and tirzepatide respectively)
  • +100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

  • Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
  • Founding year, headquarters city, and corporate ownership are not publicly disclosed
  • Promotional $99-$133 pricing applies to the introductory offer landing only, standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
  • Once medication is dispensed/shipped, prescriptions cannot be returned or refunded, typical for compounded telehealth but worth understanding
  • Lab requirements before prescribing are not disclosed on public pages, unclear whether baseline bloodwork is required
  • Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

Our Verdict

Direct Meds GLP-1 edges out Novi with a score of 7.9/10 vs 7.8/10. If budget is your priority, Novi starts at $133/mo compared to Direct Meds GLP-1's $297/mo. Choose Direct Meds GLP-1 if you want: users wanting simple, all-inclusive pricing without insurance. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer.

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Direct Meds GLP-1 nor Novi feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Try Direct Meds GLP-1

Starting at $297/mo

Visit Direct Meds GLP-1

Try Novi

Starting at $133/mo

Visit Novi

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

Embody

7.3/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.