Direct Meds GLP-1 vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Direct Meds GLP-1 scores higher on our rubric, 7.9/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Direct Meds GLP-1 - our pick of these two →or find your match

Direct Meds GLP-1 beats Willow overall, scoring 7.9/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Direct Meds GLP-1 is from $297/mo; Willow is from $299/mo. Choose Direct Meds GLP-1 for users who value published format-specific pricing and can independently monitor billing and cancellation. Choose Willow for users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

A side-by-side look at Direct Meds GLP-1 and Willow to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Direct Meds GLP-1

#8 of 54

7.9/10

Compounded GLP-1 program with published format-specific prices, offset by a sharply negative BBB complaint record around billing, cancellation, and fulfillment.

Visit Direct Meds GLP-1

Willow

#20 of 54

7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

Visit Willow

Feature	Direct Meds GLP-1	Willow
Why each one	Thorough clinical consultations focused on medical-grade patient experience rather than quick-turnaround prescribing.	One of the few compounded-only platforms offering both injectable and daily oral semaglutide tablets, useful for users who want a non-injectable option without leaving the GLP-1 compounded category.
Our Score	7.9/10	7.5/10
Headline Price	from $297/mo	from $299/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Users who value published format-specific pricing and can independently monitor billing and cancellation	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Watch out for	Compounded medications only, no brand-name Wegovy, Zepbound, or Ozempic on the menu	Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking	#8	#20
Get started	Visit Direct Meds GLP-1	Visit Willow

Pros & Cons Compared

Direct Meds GLP-1

Pros

+The published $297/mo compounded semaglutide injection tier includes medication, consultations, shipping, and pharmacy fees
+Format-specific prices are published on the site, which makes the advertised medication and service bundle easier to compare
+Fast pharmacy fulfillment: most orders ship within 48 hours of provider approval
+Responsive customer support with live chat available during business hours

Cons

−Compounded medications only, no brand-name Wegovy, Zepbound, or Ozempic on the menu
−The $297/mo injectable semaglutide rate sits above Henry Meds ($199) and TrimRx (starting at $179); Direct Meds' own sublingual semaglutide drops at $179 are the budget path if the premium stings
−BBB shows 248 complaints and roughly 1.1/5 customer-review stars, with recurring reports of unauthorized charges, cancellation difficulty, billing confusion, and unfulfilled or delayed orders

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only, no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
−Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024, less track record than Ro or Hims, though growth has been fast

Our Verdict

Direct Meds GLP-1 edges out Willow with a score of 7.9/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Direct Meds GLP-1 is from $297/mo; Willow is from $299/mo.

Cheapest complete recurring price in our index

Trimi Health

$175/mo month-to-month, from $99 on a plan · 4.2/10 · Compounded

Both Direct Meds GLP-1 and Willow start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Trimi Health at $175/mo. It scores 4.2/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.