Hone Health vs SkinnyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Hone Health and SkinnyRx are tied at 7.3/10. SkinnyRx is more affordable at $199/mo vs $309/mo. Choose Hone Health for users who want a full-service health platform covering weigh. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo.

A side-by-side comparison of Hone Health and SkinnyRx covering pricing, scores, medication types, insurance, and more to help you decide.

Hone Health

#39 of 47
7.3/10

Comprehensive men's health platform that includes GLP-1 medications alongside hormone optimization and lab testing.

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SkinnyRx

#36 of 47
7.3/10

Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats — injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only — does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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FeatureHone HealthSkinnyRx
Our Score7.3/107.3/10
Starting Price$309/mo$199/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want a full-service health platform covering weight loss plus hormones and labsUsers who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point
Ranking#39#36

Pros & Cons Compared

Hone Health

Pros

  • +40+ biomarker lab panel included — the most comprehensive baseline testing of any GLP-1 telehealth provider
  • +Full health optimization platform covering hormones, longevity, and metabolic health beyond just weight loss
  • +Starts patients on gentler liraglutide before escalating — reduces first-week side effect severity
  • +Both compounded and potentially brand-name GLP-1 options available depending on clinical assessment

Cons

  • Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total — one of the most expensive options
  • Select state availability — not available nationwide, and coverage varies by specific treatment program
  • The $149/mo membership fee is required even before you can purchase any medication

SkinnyRx

Pros

  • +Five medication formats — the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
  • +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
  • +Fast onboarding: 5–10 minute online questionnaire, physician review in 24–48 hours, medication delivered in 3–7 business days with temperature-controlled shipping
  • +4,100+ Trustpilot reviews at 4.8 stars — among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

  • No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded-only model limits patients who want or need an FDA-approved finished product
  • Limited public transparency: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site
  • Cash-pay only — does not bill commercial insurance, Medicare, or Medicaid (HSA/FSA payments accepted)
  • Independent reviews flag inconsistent customer-service responsiveness, which is a real concern for a medication that requires titration support and dose-adjustment dialogue

Our Verdict

Hone Health and SkinnyRx are closely matched with identical scores of 7.3/10. If budget is your priority, SkinnyRx starts at $199/mo compared to Hone Health's $309/mo. Choose Hone Health if you want: users who want a full-service health platform covering weight loss plus hormones and labs. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point.

Try Hone Health

Starting at $309/mo

Visit Hone Health

Try SkinnyRx

Starting at $199/mo

Visit SkinnyRx
Top Picks

Three programs our readers click through most.

Eden Health GLP-1

8.9/10
$249/mo·Brand & Compounded

Sesame Care

7.9/10
$59/mo·Brand & Compounded

Sprout Health

8.8/10
$249/mo·Brand & Compounded

Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

Today's Cheapest

Sesame Care — $59/mo