Novi vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent research·How we rank →

Visit SynergyRx - $199/mo→or find your match

Novi beats SynergyRx overall, scoring 7.8/10 vs 7.6/10. Novi is more affordable at $133/mo vs $199/mo. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa. Choose SynergyRx for needle-phobic users who want oral dissolving tablets for sem.

A side-by-side look at Novi and SynergyRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Novi

#12 of 53

7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing, medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

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SynergyRx

#22 of 53

7.6/10

Bundled GLP-1 program with predictable pricing and round-the-clock support access for peace of mind.

Visit SynergyRx

Feature	Novi	SynergyRx
Our Score	7.8/10	7.6/10
Starting Price	$133/mo	$199/mo
Medication Type	Compounded	Both
Insurance Accepted	No	No
Best For	Cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer	Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included
Watch out for	Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats	Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
Ranking	#12	#22
Get started	Visit Novi	Visit SynergyRx

Pros & Cons Compared

Novi

Pros

+Six disclosed clinicians on staff, Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP), more named providers than most compounded-only platforms publish
+Month-to-month billing with no minimum commitment, cancel before any renewal date with no early-termination penalty
+Aggressive promotional pricing on the offer landing, $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
+Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
+Free 2-day shipping; same active ingredients as Wegovy/Ozempic and Mounjaro/Zepbound (semaglutide and tirzepatide respectively)
+100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
−Founding year, headquarters city, and corporate ownership are not publicly disclosed
−Promotional $99-$133 pricing applies to the introductory offer landing only, standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
−Once medication is dispensed/shipped, prescriptions cannot be returned or refunded, typical for compounded telehealth but worth understanding
−Lab requirements before prescribing are not disclosed on public pages, unclear whether baseline bloodwork is required
−Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

SynergyRx

Pros

+Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
+Free expedited shipping included with all orders
+24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
+Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

−Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
−Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
−Company history, founding date, and ownership structure are not publicly disclosed. Ask support for pharmacy and prescriber details upfront.

Our Verdict

Novi edges out SynergyRx with a score of 7.8/10 vs 7.6/10. If budget is your priority, Novi starts at $133/mo compared to SynergyRx's $199/mo. SynergyRx offers both brand-name and compounded medications, giving you more flexibility. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer. Choose SynergyRx if you want: needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Novi nor SynergyRx feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Visit TrimRx→Read our full TrimRx review