Shed vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

Shed beats SynergyRx overall, scoring 7.8/10 vs 7.6/10. Choose Shed for users who want fast delivery and a streamlined compounded gl. Choose SynergyRx for needle-phobic users who want oral dissolving tablets for sem.

A side-by-side look at Shed and SynergyRx to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Shed

#15 of 52
7.8/10

Newer GLP-1 provider focused on speed and simplicity, fast approvals, fast shipping, and a clean user experience at a competitive price point.

Visit Shed

SynergyRx

#22 of 52
7.6/10

Bundled GLP-1 program with predictable pricing and round-the-clock support access for peace of mind.

Visit SynergyRx
FeatureShedSynergyRx
Our Score7.8/107.6/10
Starting Price$199/mo$199/mo
Medication TypeBothBoth
Insurance AcceptedNoNo
Best ForUsers who want fast delivery and a streamlined compounded GLP-1 experienceNeedle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included
Ranking#15#22
Get startedVisit ShedVisit SynergyRx

Pros & Cons Compared

Shed

Pros

  • +Industry-leading delivery speed, most patients receive medication within 2-3 days of enrollment
  • +$199/mo is competitively priced for an all-inclusive compounded program with good support
  • +Streamlined onboarding with no video call, approved and shipped faster than most competitors
  • +Clean, modern UX with real-time shipping tracking and easy provider messaging

Cons

  • The core $199 program is compounded semaglutide and tirzepatide; brand-name access runs through a separate $99/mo pathway subscription with medication billed at pharmacy rates on top
  • Newer company (founded 2024) with limited long-term track record and outcome data; the 4.6/5 Trustpilot rating across 766 reviews is the strongest early evidence available
  • No insurance billing and no FSA/HSA superbills currently available
  • Clinical support is responsive (replies typically within 24 hours) but less proactive than premium platforms; a $49.99/mo premium coaching add-on covers those who want higher touch

SynergyRx

Pros

  • +Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
  • +Free expedited shipping included with all orders
  • +24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
  • +Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

  • Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
  • Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
  • Company history, founding date, and ownership structure are not publicly disclosed. Ask support for pharmacy and prescriber details upfront.

Our Verdict

Shed edges out SynergyRx with a score of 7.8/10 vs 7.6/10. Choose Shed if you want: users who want fast delivery and a streamlined compounded glp-1 experience. Choose SynergyRx if you want: needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither Shed nor SynergyRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try Shed

Starting at $199/mo

Visit Shed

Try SynergyRx

Starting at $199/mo

Visit SynergyRx

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.