TrimRx vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Yucca Health scores higher on our rubric, 7.7/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Yucca Health - our pick of these two →or find your match

Yucca Health beats TrimRx overall, scoring 7.7/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: TrimRx is published $179/mo; total not verified; Yucca Health is from $146/mo. Choose TrimRx for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).

A side-by-side look at TrimRx and Yucca Health to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

TrimRx

#47 of 54

5.3/10

Cash-pay compounded GLP-1 provider offering semaglutide and a dual-agonist option it labels 'GLP-1 + GIP.' Its landing advertises a $179 floor, while its terms list semaglutide at $199 for the first order and $299 for follow-ups, and GLP-1 + GIP at $349 then $399. That conflict, plus a corroborated billing and fulfillment complaint pattern, is central to our 5.3/10 score.

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Higher Rated

Yucca Health

#14 of 54

7.7/10

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

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Feature	TrimRx	Yucca Health
Why each one	A written lost-or-damaged shipment replacement promise and both compounded molecule classes through one intake; neither resolves the first-party price conflict or fulfillment record.	Named board-certified doctors (rare in compounded GLP-1), 24-hour async approval (no scheduled call needed), UPS 2-Day shipping, and Klarna/Affirm/Afterpay financing on the 6-month plan, a combination no other compounded-only provider at this price matches.
Our Score	5.3/10	7.7/10
Headline Price	published $179/mo; total not verified	from $146/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment	People who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay)
Watch out for	The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout	Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
Ranking	#47	#14
Get started	Visit TrimRx	Visit Yucca Health

Pros & Cons Compared

TrimRx

Pros

+Offers both compounded semaglutide and a compounded GLP-1 + GIP option through one intake
+The landing advertises a $179 entry floor, although that figure does not match the medication schedule in the official terms
+Onboarding takes under 15 minutes with same-day provider review for most applications
+Free medication replacement if your shipment is lost or damaged in transit

Cons

−The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
−Trustpilot is 3.6/5 across 5,485 reviews with 32% one-star; BBB rates TrimRx F/not accredited with 728 unanswered and 221 unresolved complaints
−The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold
−Compounded only, no brand-name Wegovy or Zepbound. Compounded drugs are not FDA-approved finished products.
−No insurance billing and no superbill for out-of-network reimbursement, so treat the monthly price as a pure cash-pay number

Yucca Health

Pros

+Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), most compounded GLP-1 providers don't publicly name their prescribers.
+4.6 stars across 1,065 verified Trustpilot reviews, 84% give 5 stars. Top complimented theme: customer service.
+Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
+Buy-now-pay-later through Klarna, Affirm, and Afterpay, unusual flexibility in this category, useful for spreading the 6-month upfront cost.
+24-hour async approval, no live video visit required. Faster onboarding than competitors that need a scheduled call.
+UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
+Replies to 100% of negative Trustpilot reviews, usually within 48 hours.

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
−The $146/mo price requires a 6-month upfront commitment (month-to-month is meaningfully more expensive). The Klarna/Affirm/Afterpay financing exists to spread exactly that upfront cost.
−No live tele-visit option, only async review. Faster, but less depth if you have a complex health history and want a provider you can talk to.
−Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
−Founders and detailed company history not on the site.
−Refund policy is mentioned but not detailed publicly, get the cancellation terms in writing before paying for the 6-month plan.

Our Verdict

Yucca Health edges out TrimRx with a score of 7.7/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: TrimRx is published $179/mo; total not verified; Yucca Health is from $146/mo.