TrimRx vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent researchHow we rank →

TrimRx beats Yucca Health overall, scoring 7.8/10 vs 7.7/10. Yucca Health is more affordable at $146/mo vs $149/mo. Choose TrimRx for users who want affordable compounded semaglutide at one flat. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want nam.

A side-by-side look at TrimRx and Yucca Health to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

TrimRx

#11 of 53
7.8/10

Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.

Visit TrimRx

Yucca Health

#17 of 53
7.7/10

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

Visit Yucca Health
FeatureTrimRxYucca Health
Our Score7.8/107.7/10
Starting Price$149/mo$146/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want affordable compounded semaglutide at one flat, all-inclusive pricePeople who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay)
Watch out forCompounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
Ranking#11#17
Get startedVisit TrimRxVisit Yucca Health

Pros & Cons Compared

TrimRx

Pros

  • +$149/mo all-inclusive for compounded semaglutide, one of the lowest prices for a full-service program
  • +Onboarding takes under 15 minutes with same-day provider review for most applications
  • +Free medication replacement if your shipment is lost or damaged in transit

Cons

  • Compounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.
  • No insurance billing and no superbill for out-of-network reimbursement, so treat the $149/mo as a pure cash-pay price

Yucca Health

Pros

  • +Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), most compounded GLP-1 providers don't publicly name their prescribers.
  • +4.6 stars across 1,065 verified Trustpilot reviews, 84% give 5 stars. Top complimented theme: customer service.
  • +Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
  • +Buy-now-pay-later through Klarna, Affirm, and Afterpay, unusual flexibility in this category, useful for spreading the 6-month upfront cost.
  • +24-hour async approval, no live video visit required. Faster onboarding than competitors that need a scheduled call.
  • +UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
  • +Replies to 100% of negative Trustpilot reviews, usually within 48 hours.

Cons

  • Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
  • The $146/mo price requires a 6-month upfront commitment (month-to-month is meaningfully more expensive). The Klarna/Affirm/Afterpay financing exists to spread exactly that upfront cost.
  • No live tele-visit option, only async review. Faster, but less depth if you have a complex health history and want a provider you can talk to.
  • Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
  • Founders and detailed company history not on the site.
  • Refund policy is mentioned but not detailed publicly, get the cancellation terms in writing before paying for the 6-month plan.

Our Verdict

TrimRx edges out Yucca Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, Yucca Health starts at $146/mo compared to TrimRx's $149/mo. Choose TrimRx if you want: users who want affordable compounded semaglutide at one flat, all-inclusive price. Choose Yucca Health if you want: people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).

Try TrimRx

Starting at $149/mo

Visit TrimRx

Try Yucca Health

Starting at $146/mo

Visit Yucca Health

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

Embody

7.3/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.