Yucca Health GLP-1 Review
Reviewed by Iacob Pastina · Independent Editor
Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Yucca Health scores 7.7/10 in our independent review, starting at $146/mo for compounded GLP-1 medications. Yucca Health is a compounded-only telehealth platform with two named board-certified prescribers (Dr. Michael Wasef MD and Dr.
Quick Facts
What We Like
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
What Could Be Better
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
✓Best For
- •Cash-pay patients who want compounded semaglutide or tirzepatide with named prescribers disclosed before enrolling
- •Users who prefer asynchronous 24-hour approval over scheduled tele-visits and value fast onboarding
- •Patients who want to spread the 6-month upfront cost via Klarna, Affirm, or Afterpay BNPL financing
- •First-time GLP-1 patients attracted to the 6-month entry pricing of $146/mo semaglutide and willing to commit to the longer plan
✗Not Ideal For
- •Patients who want FDA-approved brand-name Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo — Yucca is compounded-only
- •Users who want oral semaglutide tablets, sublingual drops, or any non-injectable GLP-1 format
- •Patients with complex medical histories who would benefit from a live clinical tele-visit and structured baseline labs before prescribing
- •Users who want month-to-month flexibility — Yucca's best pricing requires the 6-month commitment, with shorter plans materially more expensive
How Yucca Health Works
Eligibility Quiz + Intake
Complete the eligibility questionnaire (BMI ≥30, or BMI ≥27 with a weight-related condition, or BMI ≥25 by provider discretion). The quiz funnel landing puts new users through a guided journey before checkout.
24-Hour Asynchronous Provider Review
A licensed US provider (Dr. Michael Wasef MD or Dr. Andrew Sakla DO, or another Yucca-affiliated prescriber) reviews your intake within 24 hours. No live tele-visit is required — review and approval are purely asynchronous.
Pharmacy Ships With UPS 2-Day Air + Welcome Call
If approved, a licensed US compounding pharmacy fills the prescription and ships via UPS 2-Day Air with clear injection instructions. A welcome onboarding call introduces the program; ongoing dose adjustments are handled through the patient portal.
Medications Available
Pricing Details
Compounded Semaglutide+ — 6-Month Plan
$146/moStarting at $146/mo on the 6-month plan; medication + UPS 2-Day shipping + provider review + patient portal included; Klarna/Affirm/Afterpay BNPL eligible
Compounded Semaglutide+ — Shorter Plans
$175/moHigher per-month pricing on shorter 1-month and 3-month plans; first-month entry price approximately $175 for new patients
Compounded Tirzepatide+ — 6-Month Plan
$258/moStarting at $258/mo on the 6-month plan for new tirzepatide patients; pricing increases at higher dose tiers after the first month
Compounded Tirzepatide+ — Shorter Plans
$325/moHigher per-month pricing on monthly plans; verify exact rates at checkout — Yucca disclosed earlier rates of approximately $325/mo on shorter commitments
Cancellation policy: Refund policy referenced on Yucca's site but specific terms are not detailed in public-facing pages — verify the cancellation and refund window before authorizing the 6-month commitment payment
Ready to get started?
Visit Yucca HealthOur Verdict
Yucca Health is a strong mid-tier compounded GLP-1 option that earns its 7.7 score on three credentials competitors at this price level often lack: two publicly named board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous approval that beats the typical scheduled tele-visit funnel, and Klarna/Affirm/Afterpay buy-now-pay-later financing to spread the 6-month upfront cost. Pricing is competitive — $146/mo compounded semaglutide on the 6-month plan and $258/mo compounded tirzepatide are within striking distance of the cheapest compounded options. Real-world adoption is well-documented: 20,000+ patients reported, 1,000+ Trustpilot reviews at 4.4 stars, 4.8 Google rating, and 1,000+ enrollments in the last 7 days. The trade-offs are the standard set: compounded-only with no brand-name access, no oral GLP-1, no live tele-visit option in the standard intake, and a refund policy that's referenced on the site but not detailed publicly. Best for cash-pay patients who value fast async onboarding, named prescribers, and BNPL flexibility on the longer plan. Skip if you want brand-name Wegovy or Zepbound, oral GLP-1, or month-to-month billing without a 6-month commitment.
Key differentiator: Combination of disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous approval (no live visit friction), UPS 2-Day Air shipping, and Klarna/Affirm/Afterpay buy-now-pay-later financing on the 6-month commitments — a unique BNPL-plus-fast-approval profile no other compounded-only platform at this price tier currently matches.
Frequently Asked Questions
How much does Yucca Health cost?+
Who prescribes Yucca Health medications?+
How fast does Yucca approve and ship?+
Does Yucca prescribe brand-name Wegovy or Zepbound?+
What does Yucca's '+' branding mean — is B12 included?+
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