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Our Score
7.7/10
TypeCompounded
InsuranceNo
Rank#17 of 53
CompoundedBoard-certified MD/DO physiciansLegitScript CertifiedUpdated May 13, 2026
By Iacob Pastina, Independent Editor & Researcher
Reviewed & updated May 13, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

Researched against FDA labeling, published clinical-trial data (STEP-1 / SURMOUNT-1), and Yucca Health's live pages, not a paid placement.

Yucca Health logo

Yucca Health GLP-1 Review

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

Bottom line

Yucca Health has the strongest customer-experience signal of any compounded GLP-1 provider we've checked: 4.6 stars across 1,065 Trustpilot reviews, two named board-certified doctors (rare in this category), and Klarna/Affirm/Afterpay financing to spread the 6-month plan. Full verdict ↓

Independently researched. Every statistic links to a primary source (NEJM, JAMA, FDA, CMS, or the provider's official disclosures). Affiliate status never changes a provider's score; featured picks are affiliate partners, disclosed. Last verified May 13, 2026.

Clinical evidence: 20.9% average body-weight reduction at 72 weeks in SURMOUNT-1 (NEJM, 2022). Individual results vary; compounded GLP-1s are not FDA-approved.

Summarize this article with

Yucca Health scores 7.7/10 in our independent review, starting at $146/mo for compounded GLP-1 medications. Yucca Health has one of the strongest customer-experience signals in our table, 4.6 stars across 1,065 Trustpilot reviews, 84% 5-star.

What makes it different: Named board-certified doctors (rare in compounded GLP-1), 24-hour async approval (no scheduled call needed), UPS 2-Day shipping, and Klarna/Affirm/Afterpay financing on the 6-month plan, a combination no other compounded-only provider at this price matches.

At a glance

Get Yucca Health if
  • You'll commit to a 6-month plan for the $146/mo semaglutide rate
  • You value named doctors on record over the cheapest possible price
  • You want Klarna/Affirm/Afterpay to spread the upfront cost
  • You prefer fast 24-hour async approval over scheduling a video visit
Skip if
  • You need month-to-month flexibility at the lowest price
  • You need brand-name Wegovy, Zepbound, Ozempic, or Mounjaro
  • You have a complex health history that warrants a live video consultation
  • You want oral GLP-1 (Yucca is injection-only)
Sounds like you? Visit Yucca Health

Yucca Health Pros and Cons

What it costs

Headline pricing, full-year math, and how Yucca Health compares to the closest alternatives.

Quick facts

Monthly Cost
Consultation
Included
Availability
all 50 (Yucca states 'Licensed Providers in all 50 States')
Insurance
Not Accepted
Shipping
Free
Cancellation
Refund policy referenced on ...

First-year cost & how Yucca Health compares

Year-1 default math uses the 6-month plan: $146/mo × 12 = $1,752 for compounded semaglutide. Tirzepatide on the 6-month plan: $258/mo × 12 = $3,096. Shorter plans are materially more expensive ($175-$325/mo). The $146 headline price requires the 6-month commitment.

ProviderFromYear 1 totalScore
Yucca Health (reviewed)N/A$1,752N/A
Henry Meds$199/mo$2,3948.4/10
Mochi Health$178/mo$2,1367.7/10

Year 1 totals are estimated from advertised first-month and standard refill rates as of the verification date. Insurance, FSA/HSA, and promo pricing not included. Compare a deeper price breakdown on the cheapest GLP-1 providers page.

All pricing tiers

Compounded Semaglutide+, 6-Month Plan

$146/mo

Starting at $146/mo on the 6-month plan; medication + UPS 2-Day shipping + provider review + patient portal included; Klarna/Affirm/Afterpay BNPL eligible

Compounded Semaglutide+, Shorter Plans

$175/mo

Higher per-month pricing on shorter 1-month and 3-month plans; first-month entry price approximately $175 for new patients

Compounded Tirzepatide+, 6-Month Plan

$258/mo

Starting at $258/mo on the 6-month plan for new tirzepatide patients; pricing increases at higher dose tiers after the first month

Compounded Tirzepatide+, Shorter Plans

$325/mo

Higher per-month pricing on monthly plans; verify exact rates at checkout, Yucca disclosed earlier rates of approximately $325/mo on shorter commitments

Cancellation policy: Refund policy referenced on Yucca's site but specific terms are not detailed in public-facing pages, verify the cancellation and refund window before authorizing the 6-month commitment payment

Ready to check Yucca Health's pricing for yourself?

Visit Yucca Health

Common questions

Questions readers ask about Yucca Health, similar providers to compare, and quick tools.

Frequently Asked Questions

How much does Yucca Health cost?+
Compounded semaglutide starts at $146/mo on the 6-month plan. Compounded tirzepatide starts at $258/mo on the 6-month plan. Shorter plans (1-month, 3-month) are higher, about $175 for semaglutide and $325 for tirzepatide. The 6-month plan is eligible for Klarna, Affirm, or Afterpay buy-now-pay-later financing.
Who prescribes for Yucca Health?+
Two named board-certified doctors handle prescribing: Dr. Michael Wasef MD (Internal Medicine) and Dr. Andrew Sakla DO (Internal Medicine). Other affiliated providers are licensed across all 50 states. Publicly naming prescribers is rare in the compounded GLP-1 category, most competitors don't.
How fast does Yucca approve and ship?+
Provider review is async (no scheduled video visit needed) and finishes within 24 hours. Once approved, a US licensed pharmacy ships via UPS 2-Day Air. Typical signup-to-medication: 3-5 days.
Is Yucca Health legit?+
Yes. Yucca Health, Inc. is based at 9350 Wilshire Blvd, Beverly Hills, CA. They have a verified Trustpilot profile (4.6 stars across 1,065 reviews as of May 2026, 84% giving 5 stars) and a separate 4.8 Google rating. They reply to 100% of negative Trustpilot reviews within 48 hours. Two known gaps: pharmacy partner names are not disclosed (just 'U.S. licensed pharmacies'), and the refund policy is referenced but not detailed publicly, so ask support for the terms in writing before the 6-month payment.
Does Yucca prescribe brand-name Wegovy or Zepbound?+
No. Yucca is compounded-only, only compounded semaglutide and compounded tirzepatide are available. If you want brand-name Wegovy at $149/mo, look at Hers (Novo Nordisk partnership). For brand-name Zepbound, look at LillyDirect or Hims.
What does 'Semaglutide+' mean, is B12 included?+
Yucca markets its products as 'Semaglutide+' and 'Tirzepatide+' but doesn't publicly explain what the '+' represents. The product pages don't list B12 or other adjuncts as standard. If a B12 blend matters (PeterMD explicitly includes it to help with nausea), verify Yucca's exact formula with their support team before enrolling.
Can I cancel the 6-month plan?+
Yucca's site references a refund policy but doesn't detail the cancellation window or refund eligibility publicly. Before committing to the 6-month plan, ask their support team for the exact terms in writing, this is a real gap vs competitors who publish detailed refund pages.
Does Yucca take insurance?+
No. Cash-pay only. The buy-now-pay-later options (Klarna/Affirm/Afterpay) are the main way to spread the cost.

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

Embody

7.3/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.