Calibrate vs MEDVi: Which GLP-1 Provider Is Better?
Short answer: Calibrate scores higher on our rubric, 7.7/10 against 5.7/10. Full reasoning, pricing and the cases where the other one wins are below.
Calibrate beats MEDVi overall, scoring 7.7/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; MEDVi is $179 first month, then $299/mo. Choose Calibrate for users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose MEDVi for users who want both oral and injectable compounded options in one telehealth program.
A side-by-side look at Calibrate and MEDVi to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Calibrate
#16 of 54Metabolic health company offering a physician-led program restructured in 2026: a $199/mo program fee with a 3-month minimum commitment (no more $1,649 one-time enrollment fee), plus separately billed medication. The program includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.
Visit CalibrateMEDVi
#46 of 54MEDVi offers oral and injectable compounded GLP-1 care. Semaglutide is $179 for month one and $299 for refills. Trustpilot is 4.4/5 across roughly 11,000 reviews, while BBB is F/not accredited. FDA warning letter #721455 concerns misleading labeling and marketing, not an allegation that the medication was unsafe.
Visit MEDVi| Feature | Calibrate | MEDVi |
|---|---|---|
| Why each one | Physician-led metabolic program with a 10%+ weight-loss guarantee and 50% money-back, one of the few programs backing outcomes with a cash guarantee. | Oral and injectable compounded formats in one program, with micro-dosing options and a path to FDA-approved brand medication. |
| Our Score | 7.7/10 | 5.7/10 |
| Headline Price | published $199/mo; total not verified | $179 first month, then $299/mo |
| Medication Type | Both | Both |
| Insurance Accepted | Yes | No |
| Best For | Users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee | Users who want both oral and injectable compounded options in one telehealth program |
| Watch out for | $597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors | FDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medication |
| Ranking | #16 | #46 |
| Get started | Visit Calibrate | Visit MEDVi |
Pros & Cons Compared
Calibrate
Pros
- +2026 pricing rewrite, $199/mo program fee with a 3-month commitment ($597 upfront), then month-to-month; the old $1,649 one-time enrollment fee was removed
- +Board-certified physicians with metabolic health specialization lead treatment
- +10%+ body-weight-loss guarantee with 50% money-back if not met
- +Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support
Cons
- −$597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
- −Medication cost is separate and varies significantly by payer route
- −Fewer medications in the menu than larger marketplaces like Ro or Found
- −Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan
MEDVi
Pros
- +One of the few compounded providers offering both oral tablets and injectable semaglutide
- +Micro-dosing options available, can start at sub-standard doses for patients concerned about side effects
- +Sleek onboarding experience with clear progress tracking through their patient portal
- +$179 covers the first month of compounded semaglutide on the current Katalys landing, including clinician review, medication and shipping
Cons
- −FDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medication
- −Its third-party records conflict: 4.4/5 across roughly 11,000 Trustpilot reviews, but an F and no accreditation at the BBB
- −The $179 semaglutide price is introductory; the current Katalys landing says refills are $299/mo, making the first-year total $3,468 rather than $2,148
- −Brand-name Wegovy and Zepbound paths add a $99 membership plus the medication cost, which the current landing does not publish; availability can change
- −No insurance accepted, and oral compounded semaglutide has less clinical data than injectable forms
Our Verdict
Calibrate edges out MEDVi with a score of 7.7/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; MEDVi is $179 first month, then $299/mo. Calibrate accepts insurance, which can significantly reduce your out-of-pocket costs.
Read Full Reviews
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Our pick of these two: Calibrate · 7.7/10