GLP-1 quick answers

What is the cheapest way to get a GLP-1 right now?

The cheapest tracked GLP-1 program is Sesame Care at $99/mo. Among compounded programs the cheapest is HealthRX at $99/mo; among brand-name programs it is GoodRx Care at $119/mo. Compounded semaglutide and tirzepatide are consistently cheaper than brand Wegovy or Zepbound, because they are made by compounding pharmacies rather than Novo Nordisk or Eli Lilly.

Full ranking: cheapest GLP-1 programs.

Which GLP-1 program is best?

There is no single best program, because the right answer changes with what you are optimising for. Our current top-scored pick is TrimRx at 7.8/10, from $149/mo, best for users who want affordable compounded semaglutide at one flat, all-inclusive price. If price is the only constraint, Sesame Care at $99/mo is the cheapest we track. If you want brand-name Wegovy or Zepbound rather than compounded medication, the shortlist is different again.

How do you get a GLP-1 prescription online?

You complete an intake questionnaire with a telehealth provider, a licensed prescriber in your state reviews it, and if you qualify the medication ships to your door. Most programs do not require an in-person visit or prior lab work, and the whole process usually takes a few days. What varies most between providers is whether the consultation fee is bundled, whether labs cost extra, and whether the advertised price is a first-month promotional rate that steps up afterwards.

Check eligibility first with the eligibility checker.

How much does a GLP-1 cost without insurance?

Without insurance, compounded GLP-1 programs in our tracking run from $99/mo, while brand-name programs start around $119/mo. The number most people get caught by is not the headline price but the step-up: several providers advertise a first-month promotional rate and then bill a materially higher ongoing rate from month two. Of the 53 providers we track, 9 work with insurance in some form; the rest are cash-pay only.

Model your real first-year cost with the cost calculator.

What is the difference between compounded and brand-name GLP-1s?

Brand-name drugs like Wegovy, Ozempic and Zepbound are made by Novo Nordisk and Eli Lilly and are FDA-approved. Compounded versions are mixed by compounding pharmacies using the same active ingredient, semaglutide or tirzepatide, but the compounded product itself is not FDA-approved and is not reviewed for safety or efficacy the way the brand product is. Compounded is typically much cheaper, which is why most low-cost programs use it. That price gap is a real tradeoff, not a free lunch.

More detail: safety center.

Who publishes this and how do you make money?

GLP-1 Picks is an independent comparison site tracking 53 GLP-1 telehealth providers on price, safety and care quality. We earn affiliate commission when a reader signs up with some of the providers listed. Commission never affects the score: scores come from a published methodology and an evidence file, and a lower-scoring provider is never ranked above a higher-scoring one because it pays more.

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