Hone Health vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Yucca Health beats Hone Health overall, scoring 7.7/10 vs 7.3/10. Yucca Health is more affordable at $146/mo vs $309/mo. Choose Hone Health for users who want a full-service health platform covering weigh. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.
A side-by-side comparison of Hone Health and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
Hone Health
#38 of 46Comprehensive men's health platform that includes GLP-1 medications alongside hormone optimization and lab testing.
Visit Hone HealthYucca Health
#19 of 46Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Visit Yucca Health| Feature | Hone Health | Yucca Health |
|---|---|---|
| Our Score | 7.3/10 | 7.7/10 |
| Starting Price | $309/mo | $146/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want a full-service health platform covering weight loss plus hormones and labs | Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments |
| Ranking | #38 | #19 |
Pros & Cons Compared
Hone Health
Pros
- +40+ biomarker lab panel included — the most comprehensive baseline testing of any GLP-1 telehealth provider
- +Full health optimization platform covering hormones, longevity, and metabolic health beyond just weight loss
- +Starts patients on gentler liraglutide before escalating — reduces first-week side effect severity
- +Both compounded and potentially brand-name GLP-1 options available depending on clinical assessment
Cons
- −Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total — one of the most expensive options
- −Select state availability — not available nationwide, and coverage varies by specific treatment program
- −The $149/mo membership fee is required even before you can purchase any medication
Yucca Health
Pros
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
Our Verdict
Yucca Health edges out Hone Health with a score of 7.7/10 vs 7.3/10. If budget is your priority, Yucca Health starts at $146/mo compared to Hone Health's $309/mo. Choose Hone Health if you want: users who want a full-service health platform covering weight loss plus hormones and labs. Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.