Hone Health vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent researchHow we rank →

Yucca Health beats Hone Health overall, scoring 7.7/10 vs 7.3/10. Yucca Health is more affordable at $146/mo vs $309/mo. Choose Hone Health for users who want a full-service health platform covering weigh. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want nam.

A side-by-side look at Hone Health and Yucca Health to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

Hone Health

#38 of 53
7.3/10

Comprehensive men's health platform that includes GLP-1 medications alongside hormone optimization and lab testing.

Visit Hone Health
Higher Rated

Yucca Health

#17 of 53
7.7/10

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

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FeatureHone HealthYucca Health
Our Score7.3/107.7/10
Starting Price$309/mo$146/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want a full-service health platform covering weight loss plus hormones and labsPeople who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay)
Watch out forLayered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive optionsCompounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
Ranking#38#17
Get startedVisit Hone HealthVisit Yucca Health

Pros & Cons Compared

Hone Health

Pros

  • +40+ biomarker lab panel included, the most comprehensive baseline testing of any GLP-1 telehealth provider
  • +Full health optimization platform covering hormones, longevity, and metabolic health beyond just weight loss
  • +Starts patients on gentler liraglutide before escalating, reduces first-week side effect severity
  • +Both compounded and potentially brand-name GLP-1 options available depending on clinical assessment

Cons

  • Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive options
  • Select state availability, not available nationwide, and coverage varies by specific treatment program
  • The $149/mo membership fee is required even before you can purchase any medication

Yucca Health

Pros

  • +Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), most compounded GLP-1 providers don't publicly name their prescribers.
  • +4.6 stars across 1,065 verified Trustpilot reviews, 84% give 5 stars. Top complimented theme: customer service.
  • +Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
  • +Buy-now-pay-later through Klarna, Affirm, and Afterpay, unusual flexibility in this category, useful for spreading the 6-month upfront cost.
  • +24-hour async approval, no live video visit required. Faster onboarding than competitors that need a scheduled call.
  • +UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
  • +Replies to 100% of negative Trustpilot reviews, usually within 48 hours.

Cons

  • Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
  • The $146/mo price requires a 6-month upfront commitment (month-to-month is meaningfully more expensive). The Klarna/Affirm/Afterpay financing exists to spread exactly that upfront cost.
  • No live tele-visit option, only async review. Faster, but less depth if you have a complex health history and want a provider you can talk to.
  • Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
  • Founders and detailed company history not on the site.
  • Refund policy is mentioned but not detailed publicly, get the cancellation terms in writing before paying for the 6-month plan.

Our Verdict

Yucca Health edges out Hone Health with a score of 7.7/10 vs 7.3/10. If budget is your priority, Yucca Health starts at $146/mo compared to Hone Health's $309/mo. Choose Hone Health if you want: users who want a full-service health platform covering weight loss plus hormones and labs. Choose Yucca Health if you want: people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Hone Health nor Yucca Health feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Try Hone Health

Starting at $309/mo

Visit Hone Health

Try Yucca Health

Starting at $146/mo

Visit Yucca Health

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

Embody

7.3/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.