MyStart Health vs Oak Longevity: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

MyStart Health beats Oak Longevity overall, scoring 7.7/10 vs 7.5/10. Oak Longevity is more affordable at $130/mo vs $299/mo. Choose MyStart Health for users who value a money-back weight-loss guarantee and price. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound.

A side-by-side comparison of MyStart Health and Oak Longevity covering pricing, scores, medication types, insurance, and more to help you decide.

Higher Rated

MyStart Health

#21 of 42
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

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Oak Longevity

#23 of 42
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing — patients pay each month manually rather than auto-renew.

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FeatureMyStart HealthOak Longevity
Our Score7.7/107.5/10
Starting Price$299/mo$130/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoNo
Best ForUsers who value a money-back weight-loss guarantee and price-lock protectionBudget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin)
Ranking#21#23

Pros & Cons Compared

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates — a genuine differentiator
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +HSA/FSA eligible — can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only — no insurance accepted, which limits options for patients with GLP-1 coverage
  • Only available in select states — not all 50, and the exact state list isn't published
  • Compounded medications only — no brand-name GLP-1 options available

Oak Longevity

Pros

  • +$130/mo for compounded semaglutide is among the cheapest entries on the market — Sprout Health ($99) and Sesame Care ($99) are lower, but Oak undercuts most mid-tier platforms
  • +Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
  • +No-subscription model — patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
  • +Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
  • +Money-back guarantee if not approved by physician — useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Brand-name pricing ($1,200-$1,500/mo) is significantly above market — NovoCare direct pricing for Wegovy is $349/mo, LillyDirect Zepbound $299/mo. Never buy brand-name through Oak
  • No published lab panels, no specialty (obesity medicine) physicians disclosed — clinical depth is shallow
  • 'Up to 50% cheaper than competitors' marketing claim is unverified and inconsistent — depends on which competitor and which medication tier
  • 'Longevity' framing pushes users toward add-on products (NAD+, Sermorelin, Tesamorelin) that have limited clinical evidence for weight loss specifically
  • Newer brand without disclosed company history, founding date, or executive team on landing pages
  • Three-month plans are billed upfront — pricing transparency is good, but commit-up-front is a friction point for users testing the platform

Our Verdict

MyStart Health edges out Oak Longevity with a score of 7.7/10 vs 7.5/10. If budget is your priority, Oak Longevity starts at $130/mo compared to MyStart Health's $299/mo. Oak Longevity offers both brand-name and compounded medications, giving you more flexibility. Choose MyStart Health if you want: users who value a money-back weight-loss guarantee and price-lock protection. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin).

Try MyStart Health

Starting at $299/mo

Visit MyStart Health

Try Oak Longevity

Starting at $130/mo

Visit Oak Longevity
Top Picks

Three programs our readers click through most.

Eden Health GLP-1

8.9/10
$249/mo·Brand & Compounded

Sesame Care

7.9/10
$59/mo·Brand & Compounded

Sprout Health

8.8/10
$249/mo·Brand & Compounded

Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

Today's Cheapest

Sesame Care — $59/mo