MyStart Health vs Oak Longevity: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent research·How we rank →

Visit MyStart Health - our pick of these two→or find your match

MyStart Health beats Oak Longevity overall, scoring 7.7/10 vs 7.5/10. Oak Longevity is more affordable at $133/mo vs $299/mo. Choose MyStart Health for users who want a monthly price that stays locked as their do. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound.

A side-by-side look at MyStart Health and Oak Longevity to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

MyStart Health

#21 of 53

7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health

Oak Longevity

#25 of 53

7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing, patients pay each month manually rather than auto-renew.

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Feature	MyStart Health	Oak Longevity
Our Score	7.7/10	7.5/10
Starting Price	$299/mo	$133/mo
Medication Type	Compounded	Both
Insurance Accepted	No	No
Best For	Users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee	Budget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin)
Watch out for	Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here	Brand-name pricing ($1,200-$1,500/mo) is significantly above market, NovoCare sells Wegovy direct at $349/mo and LillyDirect has Zepbound at $299/mo. Use Oak for its compounded tiers and buy brand-name direct
Ranking	#21	#25
Get started	Visit MyStart Health	Visit Oak Longevity

Pros & Cons Compared

MyStart Health

Pros

+Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
+Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
+Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
+HSA/FSA eligible, can use pre-tax health savings to pay for treatment

Cons

−Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
−Select states only, not all 50, and the exact list isn't published. Confirm your state during the intake quiz before paying
−Compounded medications only, no brand-name GLP-1 option on the menu

Oak Longevity

Pros

+$133/mo for compounded semaglutide is among the cheapest entries on the market, Sesame Care ($99) is lower, but Oak undercuts most mid-tier platforms
+No-subscription model, patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
+Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
+Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
+Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
+Free shipping and free health coaching included in every program

Cons

−Brand-name pricing ($1,200-$1,500/mo) is significantly above market, NovoCare sells Wegovy direct at $349/mo and LillyDirect has Zepbound at $299/mo. Use Oak for its compounded tiers and buy brand-name direct
−No published lab panels and no specialty (obesity medicine) physicians disclosed, clinical oversight is lighter than lab-driven platforms
−The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
−The longevity add-ons (NAD+, Sermorelin, Tesamorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
−Newer brand without disclosed company history, founding date, or executive team on landing pages
−Three-month plans are billed upfront, start on the 1-month plan if you're testing the platform, then bundle once it fits

Our Verdict

MyStart Health edges out Oak Longevity with a score of 7.7/10 vs 7.5/10. If budget is your priority, Oak Longevity starts at $133/mo compared to MyStart Health's $299/mo. Oak Longevity offers both brand-name and compounded medications, giving you more flexibility. Choose MyStart Health if you want: users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin).

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither MyStart Health nor Oak Longevity feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Visit TrimRx→Read our full TrimRx review