Oak Longevity vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Yucca Health beats Oak Longevity overall, scoring 7.7/10 vs 7.5/10. Oak Longevity is more affordable at $130/mo vs $146/mo. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.

A side-by-side comparison of Oak Longevity and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.

Oak Longevity

#26 of 46
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing — patients pay each month manually rather than auto-renew.

Visit Oak Longevity
Higher Rated

Yucca Health

#19 of 46
7.7/10

Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.

Visit Yucca Health
FeatureOak LongevityYucca Health
Our Score7.5/107.7/10
Starting Price$130/mo$146/mo
Medication TypeBothCompounded
Insurance AcceptedNoNo
Best ForBudget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin)Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments
Ranking#26#19

Pros & Cons Compared

Oak Longevity

Pros

  • +$130/mo for compounded semaglutide is among the cheapest entries on the market — Sprout Health ($99) and Sesame Care ($99) are lower, but Oak undercuts most mid-tier platforms
  • +Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
  • +No-subscription model — patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
  • +Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
  • +Money-back guarantee if not approved by physician — useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Brand-name pricing ($1,200-$1,500/mo) is significantly above market — NovoCare direct pricing for Wegovy is $349/mo, LillyDirect Zepbound $299/mo. Never buy brand-name through Oak
  • No published lab panels, no specialty (obesity medicine) physicians disclosed — clinical depth is shallow
  • 'Up to 50% cheaper than competitors' marketing claim is unverified and inconsistent — depends on which competitor and which medication tier
  • 'Longevity' framing pushes users toward add-on products (NAD+, Sermorelin, Tesamorelin) that have limited clinical evidence for weight loss specifically
  • Newer brand without disclosed company history, founding date, or executive team on landing pages
  • Three-month plans are billed upfront — pricing transparency is good, but commit-up-front is a friction point for users testing the platform

Yucca Health

Pros

  • +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
  • +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
  • +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
  • +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
  • +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
  • +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)

Cons

  • Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
  • Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
  • No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
  • Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
  • B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
  • Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan

Our Verdict

Yucca Health edges out Oak Longevity with a score of 7.7/10 vs 7.5/10. If budget is your priority, Oak Longevity starts at $130/mo compared to Yucca Health's $146/mo. Oak Longevity offers both brand-name and compounded medications, giving you more flexibility. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin). Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.

Try Oak Longevity

Starting at $130/mo

Visit Oak Longevity

Try Yucca Health

Starting at $146/mo

Visit Yucca Health
Top Picks

Three programs our readers click through most.

Eden Health GLP-1

8.9/10
$249/mo·Brand & Compounded

Sesame Care

7.9/10
$59/mo·Brand & Compounded

Sprout Health

8.8/10
$249/mo·Brand & Compounded

Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

Today's Cheapest

Sesame Care — $59/mo