Sesame Care vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 7.7/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Sesame Care - our pick of these two →or find your match

Sesame Care beats Yucca Health overall, scoring 7.9/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Yucca Health is from $146/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).

A side-by-side look at Sesame Care and Yucca Health to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Sesame Care

#5 of 54

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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Yucca Health

#14 of 54

7.7/10

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

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Feature	Sesame Care	Yucca Health
Why each one	The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.	Named board-certified doctors (rare in compounded GLP-1), 24-hour async approval (no scheduled call needed), UPS 2-Day shipping, and Klarna/Affirm/Afterpay financing on the 6-month plan, a combination no other compounded-only provider at this price matches.
Our Score	7.9/10	7.7/10
Headline Price	published $99/mo; total not verified	from $146/mo
Medication Type	Both	Compounded
Insurance Accepted	Yes	No
Best For	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber	People who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay)
Watch out for	Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout	Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
Ranking	#5	#14
Get started	Visit Sesame Care	Visit Yucca Health

Pros & Cons Compared

Sesame Care

Pros

+Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
+Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
−The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
−Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
−A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Yucca Health

Pros

+Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), most compounded GLP-1 providers don't publicly name their prescribers.
+4.6 stars across 1,065 verified Trustpilot reviews, 84% give 5 stars. Top complimented theme: customer service.
+Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
+Buy-now-pay-later through Klarna, Affirm, and Afterpay, unusual flexibility in this category, useful for spreading the 6-month upfront cost.
+24-hour async approval, no live video visit required. Faster onboarding than competitors that need a scheduled call.
+UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
+Replies to 100% of negative Trustpilot reviews, usually within 48 hours.

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
−The $146/mo price requires a 6-month upfront commitment (month-to-month is meaningfully more expensive). The Klarna/Affirm/Afterpay financing exists to spread exactly that upfront cost.
−No live tele-visit option, only async review. Faster, but less depth if you have a complex health history and want a provider you can talk to.
−Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
−Founders and detailed company history not on the site.
−Refund policy is mentioned but not detailed publicly, get the cancellation terms in writing before paying for the 6-month plan.

Our Verdict

Sesame Care edges out Yucca Health with a score of 7.9/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Yucca Health is from $146/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility.