Sesame Care vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Sesame Care beats Yucca Health overall, scoring 7.9/10 vs 7.7/10. Sesame Care is more affordable at $59/mo vs $146/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.
A side-by-side comparison of Sesame Care and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
Sesame Care
#10 of 46Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications — including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.
Visit Sesame CareYucca Health
#19 of 46Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Visit Yucca Health| Feature | Sesame Care | Yucca Health |
|---|---|---|
| Our Score | 7.9/10 | 7.7/10 |
| Starting Price | $59/mo | $146/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber | Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments |
| Ranking | #10 | #19 |
Pros & Cons Compared
Sesame Care
Pros
- +Success by Sesame program launched 2026 — $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
- +Brand-name cash pricing is competitive — Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Membership model adds complexity — two distinct products (pay-per-visit vs Success membership) can be confusing
- −Success by Sesame requires a 3-month minimum commitment to hit the $59/mo rate
- −Compounded meds are de-emphasized on the current marketing — focus has shifted to FDA-approved brand-name paths
- −Less hand-holding than dedicated subscription platforms like Willow or Eden Health
Yucca Health
Pros
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
Our Verdict
Sesame Care edges out Yucca Health with a score of 7.9/10 vs 7.7/10. If budget is your priority, Sesame Care starts at $59/mo compared to Yucca Health's $146/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.