GLP-1 Dosing Timeline — What to Expect Week by Week
A visual guide to your GLP-1 titration schedule. See the exact doses, common side effects, and practical tips for every phase of treatment — from your first injection to maintenance.
Mild nausea possible. Most people tolerate this starter dose well with minimal disruption.
Eat smaller, more frequent meals. Stay well hydrated. Inject on the same day each week to build a routine.
Nausea may increase. Appetite suppression becomes noticeable. Some experience constipation or mild headaches.
Avoid high-fat or greasy foods. Keep bland snacks on hand (crackers, toast). Ginger tea can ease nausea.
GI side effects peak for many patients. Significant appetite changes. Nausea, diarrhea, or constipation possible.
This is often the hardest phase — it gets better. Prioritize protein at every meal. Talk to your provider if symptoms are severe.
Body is adapting. Side effects typically improving. Continued strong appetite suppression.
Focus on nutrient-dense foods since you are eating less. Light exercise (walking 20-30 min) helps digestion and mood.
Full therapeutic dose. Most side effects have resolved. Steady-state weight loss continues.
This is your maintenance dose. Continue healthy habits. Regular check-ins with your provider every 3-6 months.
Frequently Asked Questions
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Take the Match Quiz →Disclaimer: This dosing timeline is based on FDA-approved prescribing information for Wegovy (semaglutide 2.4 mg), Ozempic (semaglutide 1 mg/2 mg), Zepbound/Mounjaro (tirzepatide), and Rybelsus (oral semaglutide). Side effect descriptions are based on clinical trial data. This tool is for informational purposes only and does not constitute medical advice. Always follow your healthcare provider's prescribed titration schedule.