Calibrate vs Oak Longevity: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Calibrate scores higher on our rubric, 7.7/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

Calibrate beats Oak Longevity overall, scoring 7.7/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Oak Longevity is from $167/mo. Choose Calibrate for insured users who want a clinician-led metabolic health program on a three-month commitment, with brand-name glp-1s only and medication plus labs billed to their own plan. Choose Oak Longevity for budget-conscious users who want one of the cheapest compounded glp-1 entries, a flat price across every dose, and a longevity-stack add-on (nad+, glutathione, sermorelin).

A side-by-side look at Calibrate and Oak Longevity to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Calibrate

#14 of 54
7.7/10

Metabolic health company offering a clinician-led program restructured in 2026: a $199/mo program fee across a three-month minimum commitment, $597 in total (no more $1,649 one-time enrollment fee), with medication and lab tests both billed separately. The membership covers a 20-minute clinician visit with lab review, 1:1 coaching, a smart scale and insurance navigation. Calibrate prescribes brand-name GLP-1s only and says on its medication page that it does not prescribe compounded GLP-1s.

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Oak Longevity

#18 of 54
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, across injectable and non-injectable routes, alongside a longevity stack (NAD+, Glutathione, Sermorelin). Every dose is priced the same, so titrating up does not raise the monthly cost. Plans run as a subscription that renews automatically and can be cancelled from the account at any time.

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FeatureCalibrateOak Longevity
Why each onePhysician-led metabolic program with a 10%+ weight-loss guarantee and 50% money-back, one of the few programs backing outcomes with a cash guarantee.
One price per medication regardless of dose, so titrating up does not raise the bill. Combined with three compounded routes and a longevity peptide menu, Oak reads as a 'menu' platform rather than the typical single-product flow.
Our Score7.7/107.5/10
Headline Pricepublished $199/mo; total not verifiedfrom $167/mo
Medication TypeBrandCompounded
Insurance AcceptedYesNo
Best ForInsured users who want a clinician-led metabolic health program on a three-month commitment, with brand-name GLP-1s only and medication plus labs billed to their own plan
Budget-conscious users who want one of the cheapest compounded GLP-1 entries, a flat price across every dose, and a longevity-stack add-on (NAD+, Glutathione, Sermorelin)
Watch out forThe first three months are locked in: the membership terms give no refunds once a month is paid and no waiver of the remaining installments if you stop early, so leaving in month two still costs the full $597
Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
Ranking#14#18
Get startedVisit CalibrateVisit Oak Longevity

Pros & Cons Compared

Calibrate

Pros

  • +2026 pricing rewrite: a $199/mo program fee billed as three monthly installments across the commitment, $597 in total, then month to month; the old $1,649 one-time enrollment fee is gone
  • +Clinicians are US-licensed and board-certified, described on the site's FAQ as nurse practitioners, and Calibrate names its chief medical officer on the medication page
  • +10% weight-loss guarantee that pays back 50% of membership fees, though only after 12 consecutive self-paid months
  • +Nutrition coaching, a personalized smart scale, sleep and exercise support, and full insurance navigation are all inside the $199 fee

Cons

  • The first three months are locked in: the membership terms give no refunds once a month is paid and no waiver of the remaining installments if you stop early, so leaving in month two still costs the full $597
  • Both medication and lab tests are billed outside the $199 fee, so your real monthly cost depends on your own insurance plan rather than on the headline price
  • Brand-name GLP-1s only, with no cash-pay compounded lane, so if your insurance denies coverage there is no cheaper in-house option to fall back on
  • You wait one to two weeks before a clinician sees you: the published timeline puts signup on day 1, blood work in days 1 to 5, and lab results plus your first clinician visit in days 7 to 14

Oak Longevity

Pros

  • +A $167/mo starting price on its compounded semaglutide page, with no membership fee, free shipping and free health coaching included
  • +Every dose costs the same, so moving to a higher dose during titration does not raise the monthly bill, stated on the product page and in the blog
  • +Three compounded routes including a non-injectable oral or sublingual option, unusual at this price
  • +Longevity peptides (NAD+, Glutathione, Sermorelin) sit alongside the GLP-1 menu on one platform
  • +Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
  • Obesity-certified doctors are advertised on the weight loss page, but no clinician roster or credentials are published, and no lab panels or blood work are offered anywhere on the site (rendered check 2026-09-03)
  • The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
  • The longevity add-ons it lists (NAD+, Glutathione, Sermorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
  • The operating entity appears only in the footer and legal pages, as Leaf Longevity Holdings Corp trading as Oak Longevity, and no founding date, named leadership, about page or team page exists on the site (rendered check 2026-09-03)
  • Its published starting price is not consistent: $119 a month in the homepage FAQ, $167 on the compounded semaglutide page, $180 in its own blog and $190 on the weight loss page, so settle the figure at checkout before you commit

Our Verdict

Calibrate edges out Oak Longevity with a score of 7.7/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Oak Longevity is from $167/mo. Calibrate accepts insurance, which can significantly reduce your out-of-pocket costs.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both Calibrate and Oak Longevity start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Try Oak Longevity

Headline price: from $167/mo

Visit Oak Longevity

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