Calibrate vs Sesame Care: Which GLP-1 Provider Is Better?
Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 7.7/10. Full reasoning, pricing and the cases where the other one wins are below.
Sesame Care beats Calibrate overall, scoring 7.9/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Sesame Care is published $99/mo; total not verified. Choose Calibrate for users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.
A side-by-side look at Calibrate and Sesame Care to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Calibrate
#16 of 54Metabolic health company offering a physician-led program restructured in 2026: a $199/mo program fee with a 3-month minimum commitment (no more $1,649 one-time enrollment fee), plus separately billed medication. The program includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.
Visit CalibrateSesame Care
#5 of 54Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.
Visit Sesame Care| Feature | Calibrate | Sesame Care |
|---|---|---|
| Why each one | Physician-led metabolic program with a 10%+ weight-loss guarantee and 50% money-back, one of the few programs backing outcomes with a cash guarantee. | The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication. |
| Our Score | 7.7/10 | 7.9/10 |
| Headline Price | published $199/mo; total not verified | published $99/mo; total not verified |
| Medication Type | Both | Both |
| Insurance Accepted | Yes | Yes |
| Best For | Users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber |
| Watch out for | $597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors | Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout |
| Ranking | #16 | #5 |
| Get started | Visit Calibrate | Visit Sesame Care |
Pros & Cons Compared
Calibrate
Pros
- +2026 pricing rewrite, $199/mo program fee with a 3-month commitment ($597 upfront), then month-to-month; the old $1,649 one-time enrollment fee was removed
- +Board-certified physicians with metabolic health specialization lead treatment
- +10%+ body-weight-loss guarantee with 50% money-back if not met
- +Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support
Cons
- −$597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
- −Medication cost is separate and varies significantly by payer route
- −Fewer medications in the menu than larger marketplaces like Ro or Found
- −Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan
Sesame Care
Pros
- +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
- +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
- −The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
- −Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
- −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms
Our Verdict
Sesame Care edges out Calibrate with a score of 7.9/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Sesame Care is published $99/mo; total not verified.
Read Full Reviews
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Our pick of these two: Sesame Care · 7.9/10