Calibrate vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Sesame Care beats Calibrate overall, scoring 7.9/10 vs 7.7/10. Sesame Care is more affordable at $99/mo vs $199/mo. Choose Calibrate for users who want a physician-led metabolic health program with. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.

A side-by-side comparison of Calibrate and Sesame Care covering pricing, scores, medication types, insurance, and more to help you decide.

Calibrate

#21 of 48

7.7/10

Metabolic health company offering a physician-led GLP-1 program restructured in 2026: $199/mo with a 3-month minimum commitment (no more $1,649 one-time enrollment fee). Includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.

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Higher Rated

Sesame Care

#10 of 48

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications — including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.

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Feature	Calibrate	Sesame Care
Our Score	7.7/10	7.9/10
Starting Price	$199/mo	$99/mo
Medication Type	Both	Both
Insurance Accepted	Yes	Yes
Best For	Users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Ranking	#21	#10

Pros & Cons Compared

Calibrate

Pros

+2026 pricing rewrite — flat $199/mo with 3-month commitment ($597 upfront), then month-to-month. The old $1,649 one-time enrollment fee was removed.
+Board-certified physicians with metabolic health specialization lead treatment
+10%+ body-weight-loss guarantee with 50% money-back if not met
+Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support

Cons

−$597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
−Medication cost is separate and varies significantly by payer route
−Fewer medications in the menu than larger marketplaces like Ro or Found
−Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan

Sesame Care

Pros

+Success by Sesame program launched 2026 — $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
+Brand-name cash pricing is competitive — Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Membership model adds complexity — two distinct products (pay-per-visit vs Success membership) can be confusing
−Success by Sesame requires a 3-month minimum commitment to hit the $59/mo rate
−Compounded meds are de-emphasized on the current marketing — focus has shifted to FDA-approved brand-name paths
−Less hand-holding than dedicated subscription platforms like Willow or Sprout Health

Our Verdict

Sesame Care edges out Calibrate with a score of 7.9/10 vs 7.7/10. If budget is your priority, Sesame Care starts at $99/mo compared to Calibrate's $199/mo. Choose Calibrate if you want: users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Still undecided? Editor's #1 Overall Pick

Embody

$299/mo · 7.3/10 · Compounded

If neither Calibrate nor Sesame Care feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Embody — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Embody→Read our full Embody review