Henry Meds vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Henry Meds scores higher on our rubric, 8.4/10 against 7.9/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Sesame Care - published $99/mo; total not verified →or find your match

Henry Meds beats Sesame Care overall, scoring 8.4/10 vs 7.9/10. Published pricing is not a like-for-like monthly comparison: Henry Meds is from $199/mo; Sesame Care is published $99/mo; total not verified. Choose Henry Meds for people who want the highest-volume trustpilot record we've found (12,461 reviews at 4.5★) plus the flexibility to switch between compounded and brand-name medications under one subscription. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

A side-by-side look at Henry Meds and Sesame Care to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Henry Meds

#3 of 54

8.4/10

Online weight-loss program by Henry Meds, based in Dover, Delaware. Among the largest customer-experience footprints we've checked: 4.5 stars across 12,461 verified Trustpilot reviews, 85% giving 5 stars. Covers compounded semaglutide and tirzepatide (custom-made versions, not the FDA-approved brand) AND brand-name Wegovy and Zepbound. You can switch between medication types without re-enrolling. $199/mo entry price for compounded with monthly provider check-ins included.

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Sesame Care

#5 of 54

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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Feature	Henry Meds	Sesame Care
Why each one	The Trustpilot signal: 12,461 verified reviews at 4.5 stars is the largest customer-experience record in our table. Most competitors have under 5,000 reviews; Henry has built up real-world adoption over time. Plus medication flexibility, they cover compounded AND brand-name.	The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.
Our Score	8.4/10	7.9/10
Headline Price	from $199/mo	published $99/mo; total not verified
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	People who want the highest-volume Trustpilot record we've found (12,461 reviews at 4.5★) plus the flexibility to switch between compounded and brand-name medications under one subscription.	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Watch out for	Pharmacy partner not publicly named on the site, Henry says 'licensed pharmacies' but doesn't name a specific facility. The previously-circulated 'Strive Pharmacy' name is not confirmed on Henry's current public-facing pages.	Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
Ranking	#3	#5
Get started	Visit Henry Meds	Visit Sesame Care

Pros & Cons Compared

Henry Meds

Pros

+Verified Trustpilot record is the largest in our table: 4.5 stars across 12,461 reviews (May 2026), 85% give 5 stars.
+Replies to 100% of negative reviews, typically within 24 hours.
+Both compounded AND brand-name (Wegovy, Zepbound) under one subscription, most providers force you to pick one path.
+Easy medication switching through the patient portal. If compounded isn't working, you can move to brand-name without re-enrolling.
+Cancel anytime, no fees. Provides superbills for FSA/HSA reimbursement.

Cons

−Pharmacy partner not publicly named on the site, Henry says 'licensed pharmacies' but doesn't name a specific facility. The previously-circulated 'Strive Pharmacy' name is not confirmed on Henry's current public-facing pages.
−Cash-pay only, $199/mo is entirely out-of-pocket (though FSA/HSA superbills are available).
−7% of Trustpilot reviews are 1-star, the common theme is operational/communication issues with specific providers, not pricing surprises.
−Consultation wait times can stretch 3-5 days during peak periods (January, post-holiday).

Sesame Care

Pros

+Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
+Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
−The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
−Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
−A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Henry Meds edges out Sesame Care with a score of 8.4/10 vs 7.9/10. Published pricing is not a like-for-like monthly comparison: Henry Meds is from $199/mo; Sesame Care is published $99/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs.