Henry Meds vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

Henry Meds beats Sesame Care overall, scoring 8.4/10 vs 7.9/10. Sesame Care is more affordable at $99/mo vs $199/mo. Choose Henry Meds for people who want the highest-volume trustpilot record we've f. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.

A side-by-side look at Henry Meds and Sesame Care to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Henry Meds

#4 of 52
8.4/10

Online weight-loss program by Henry Meds, based in Dover, Delaware. Among the largest customer-experience footprints we've checked: 4.5 stars across 12,461 verified Trustpilot reviews, 85% giving 5 stars. Covers compounded semaglutide and tirzepatide (custom-made versions, not the FDA-approved brand) AND brand-name Wegovy and Zepbound. You can switch between medication types without re-enrolling. $199/mo entry price for compounded with monthly provider check-ins included.

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Sesame Care

#7 of 52
7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications, including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.

Visit Sesame Care
FeatureHenry MedsSesame Care
Our Score8.4/107.9/10
Starting Price$199/mo$99/mo
Medication TypeBothBoth
Insurance AcceptedNoYes
Best ForPeople who want the highest-volume Trustpilot record we've found (12,461 reviews at 4.5★) plus the flexibility to switch between compounded and brand-name medications under one subscription.Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Ranking#4#7
Get startedVisit Henry MedsVisit Sesame Care

Pros & Cons Compared

Henry Meds

Pros

  • +Verified Trustpilot record is the largest in our table: 4.5 stars across 12,461 reviews (May 2026), 85% give 5 stars.
  • +Replies to 100% of negative reviews, typically within 24 hours.
  • +Both compounded AND brand-name (Wegovy, Zepbound) under one subscription, most providers force you to pick one path.
  • +Easy medication switching through the patient portal. If compounded isn't working, you can move to brand-name without re-enrolling.
  • +Cancel anytime, no fees. Provides superbills for FSA/HSA reimbursement.

Cons

  • Pharmacy partner not publicly named on the site, Henry says 'licensed pharmacies' but doesn't name a specific facility. The previously-circulated 'Strive Pharmacy' name is not confirmed on Henry's current public-facing pages.
  • Cash-pay only, $199/mo is entirely out-of-pocket (though FSA/HSA superbills are available).
  • 7% of Trustpilot reviews are 1-star, the common theme is operational/communication issues with specific providers, not pricing surprises.
  • Consultation wait times can stretch 3-5 days during peak periods (January, post-holiday).

Sesame Care

Pros

  • +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

  • Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
  • The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
  • Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Henry Meds edges out Sesame Care with a score of 8.4/10 vs 7.9/10. If budget is your priority, Sesame Care starts at $99/mo compared to Henry Meds's $199/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Choose Henry Meds if you want: people who want the highest-volume trustpilot record we've found (12,461 reviews at 4.5★) plus the flexibility to switch between compounded and brand-name medications under one subscription.. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither Henry Meds nor Sesame Care feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try Henry Meds

Starting at $199/mo

Visit Henry Meds

Try Sesame Care

Starting at $99/mo

Visit Sesame Care

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.