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Enhance MD vs Novi: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Enhance MD and Novi are tied at 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Novi is from $133/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Novi for cash-pay patients who want compounded semaglutide or tirzepa.

A side-by-side look at Enhance MD and Novi to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

Enhance MD

#13 of 54
7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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Novi

#9 of 54
7.8/10

Telehealth platform for compounded semaglutide and tirzepatide with month-to-month billing, six named clinicians on staff, and a 3-minute pre-approval quiz. Novi emphasizes 'all-in transparent' pricing, medication, supplies, unlimited clinician check-ins, dose adjustments, and weight-loss coaching are bundled with no add-on fees. Standard pricing is $174/mo semaglutide and $283/mo tirzepatide; promotional pricing on the offer landing drops to $99-$133/mo semaglutide and $149-$166/mo tirzepatide with $200 off advertised.

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FeatureEnhance MDNovi
Why each oneThe most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.Combination of six named clinicians (most compounded-only platforms disclose zero or one), month-to-month billing with no commitment, and aggressive promotional pricing as low as $99/mo on the offer landing, a flexibility-and-headcount profile most direct competitors at this price tier do not match.
Our Score7.8/107.8/10
Headline Pricefrom $212/mofrom $133/mo
Medication TypeBothCompounded
Insurance AcceptedNoNo
Best ForBudget-conscious users interested in combination therapiesCash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer
Watch out forCheck-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadenceCompounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
Ranking#13#9
Get startedVisit Enhance MDVisit Novi

Pros & Cons Compared

Enhance MD

Pros

  • +GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
  • +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
  • +Quick asynchronous consultations, most patients approved within 24 hours without video calls
  • +Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

  • Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
  • No insurance billing, and customer support runs business days only, no weekends

Novi

Pros

  • +Six disclosed clinicians on staff, Daniel Funsch MD, Michael Wasef MD, Takashi Nakamura MD plus three nurse practitioners (Hastings NP, Clements NP, Vergara DNP), more named providers than most compounded-only platforms publish
  • +Month-to-month billing with no minimum commitment, cancel before any renewal date with no early-termination penalty
  • +Aggressive promotional pricing on the offer landing, $99-$133/mo compounded semaglutide and $149-$166/mo compounded tirzepatide with a $200 OFF intro discount
  • +Unlimited clinician check-ins, dose adjustments, and weight-loss coaching included at no additional cost
  • +Free 2-day shipping; Novi markets compounded semaglutide and tirzepatide, which are not FDA-approved brands or generics and are not established as equivalent to Wegovy, Ozempic, Mounjaro, or Zepbound
  • +100,000+ patients claimed and editorial coverage in Bloomberg, Forbes, and WebMD provide third-party signal

Cons

  • Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro through the platform; no Foundayo or oral GLP-1 formats
  • Founding year, headquarters city, and corporate ownership are not publicly disclosed
  • Promotional $99-$133 pricing applies to the introductory offer landing only, standard rate after any qualifying intro period is $174-$283/mo (verify the renewal rate before enrolling)
  • Once medication is dispensed/shipped, prescriptions cannot be returned or refunded, typical for compounded telehealth but worth understanding
  • Lab requirements before prescribing are not disclosed on public pages, unclear whether baseline bloodwork is required
  • Multiple landing pages (offer-v4, offer-v6-low) show different headline prices, which can create pricing confusion before checkout

Our Verdict

Enhance MD and Novi are closely matched with identical scores of 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Novi is from $133/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose Novi if you want: cash-pay patients who want compounded semaglutide or tirzepatide on a no-commitment plan with named clinicians, unlimited check-ins, and aggressive promotional pricing as low as $99-$133/mo on the introductory offer.

Try Enhance MD

Headline price: from $212/mo

Visit Enhance MD

Try Novi

Headline price: from $133/mo

Visit Novi

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