Enhance MD vs Fridays: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Fridays scores higher on our rubric, 8.7/10 against 7.8/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Enhance MD - from $212/mo →or find your match

Fridays beats Enhance MD overall, scoring 8.7/10 vs 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Fridays is $249/mo month-to-month. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Fridays for users who want a holistic program with coaching, nutrition support, and flexible pricing.

A side-by-side look at Enhance MD and Fridays to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Enhance MD

#13 of 54

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Visit Enhance MD

Higher Rated

Fridays

#1 of 54

8.7/10

Holistic weight loss program combining GLP-1 medications with lifestyle coaching, nutrition guidance, and ongoing support.

Visit Fridays

Feature	Enhance MD	Fridays
Why each one	The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.	One of the only GLP-1 platforms that combines direct insurance billing with integrated nutrition coaching, making it both the most affordable (with insurance) and most comprehensive option.
Our Score	7.8/10	8.7/10
Headline Price	from $212/mo	$249/mo month-to-month
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Budget-conscious users interested in combination therapies	Users who want a holistic program with coaching, nutrition support, and flexible pricing
Watch out for	Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence	The coaching-heavy model adds complexity, three different plan tiers with different inclusions
Ranking	#13	#1
Get started	Visit Enhance MD	Visit Fridays

Pros & Cons Compared

Enhance MD

Pros

+GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations, most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
−No insurance billing, and customer support runs business days only, no weekends

Fridays

Pros

+One of the few platforms that bills insurance directly, can reduce out-of-pocket to $25-50/mo with coverage
+Includes 1-on-1 nutrition coaching and weekly check-ins, not just medication prescriptions
+Offers brand-name Wegovy/Zepbound and compounded options, switches based on insurance formulary
+Flexible plans: medication-only ($249/mo) or full coaching program ($299/mo)

Cons

−The coaching-heavy model adds complexity, three different plan tiers with different inclusions
−Without insurance, $249/mo for medication-only is above average for what you get clinically

Our Verdict

Fridays edges out Enhance MD with a score of 8.7/10 vs 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Fridays is $249/mo month-to-month. Fridays accepts insurance, which can significantly reduce your out-of-pocket costs.