Enhance MD vs Fridays: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
34 providers verified independently·Independent researchHow we rank →

Short answer: Fridays scores higher on our rubric, 8.7/10 against 7.8/10. Full reasoning, pricing and the cases where the other one wins are below.

Fridays beats Enhance MD overall, scoring 8.7/10 vs 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Fridays is from $117/mo. Choose Enhance MD for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it. Choose Fridays for users who want a holistic program with coaching, nutrition support, and flexible pricing.

A side-by-side look at Enhance MD and Fridays to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

Enhance MD

#8 of 34
7.8/10

Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).

Visit Enhance MD
Higher Rated

Fridays

#1 of 34
8.7/10

Holistic weight loss program combining GLP-1 medications with lifestyle coaching, nutrition guidance, and ongoing support.

Visit Fridays
FeatureEnhance MDFridays
Why each oneThe most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.
A bundled program rather than a prescribe and ship service. Unlimited provider visits, nutrition and mental health coaching and 1-on-1 dietitian support are included in the monthly price with no separate membership fee, and compounded and brand-name GLP-1s are sold side by side on the same page.
Our Score7.8/108.7/10
Headline Pricefrom $212/mofrom $117/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoNo
Best ForCash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it
Users who want a holistic program with coaching, nutrition support, and flexible pricing
Watch out forThe $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
The lowest advertised compounded prices require an annual commitment and a promo code
Ranking#8#1
Get startedVisit Enhance MDVisit Fridays

Pros & Cons Compared

Enhance MD

Pros

  • +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
  • +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
  • +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
  • +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding

Cons

  • The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
  • Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
  • Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
  • Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)

Fridays

Pros

  • +Compounded semaglutide runs as low as $117 a month on the annual plan with the NYNY12 code printed on its pricing page, against $279 month to month
  • +Includes 1-on-1 nutrition coaching and weekly check-ins, not just medication prescriptions
  • +Sells brand-name Ozempic, Zepbound and Wegovy alongside compounded semaglutide and tirzepatide, with an insurance concierge that helps you pursue coverage for the brand-name option through your own plan
  • +Membership costs nothing on top of the medication price: unlimited provider visits, nutrition and mental health coaching and 1-on-1 dietitian support are listed on every plan

Cons

  • The lowest advertised compounded prices require an annual commitment and a promo code
  • Compounded medication and virtual visits are cash-pay. Fridays offers insurance and prior-authorization support for brand-name medication, but coverage and your out-of-pocket cost depend on your plan.

Our Verdict

Fridays edges out Enhance MD with a score of 8.7/10 vs 7.8/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Fridays is from $117/mo. Fridays offers both brand-name and compounded medications, giving you more flexibility.

Try Enhance MD

Headline price: from $212/mo

Visit Enhance MD

Try Fridays

Headline price: from $117/mo

Visit Fridays

Related comparisons

More head-to-head comparisons involving Enhance MD and Fridays.

Not comparing, just asking? Quick answers to the most-asked GLP-1 questions →

Not sure which one is right for you?

Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.

Still working out whether either one is above board? We check that separately: is Enhance MD legit and is Fridays legit, with the verification evidence behind each answer.