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Enhance MD GLP-1 Review
About Enhance MD
Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).
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The price
Price checked 2026-08-28Billed every 4 weeks; $50 off the first order with the on-page SUMMER50 code
View this plan12-month-plan rate; $249/mo month-to-month, with $50-$100 first-order discounts via on-page SUMMER codes
Plans & payment terms
View treatment options at Enhance MD. Confirm the latest price and availability there.
Show all 10 plans and payment terms
What they offer
- Semaglutide (compounded, sold as GLP-1 Core)
- Tirzepatide (compounded, sold as GLP-1 Advanced)
- Semaglutide and tirzepatide in one formulation (compounded, sold as GLP-1 Elite)
- Tirzepatide, 1mg microdosing plan (compounded)
- NAD+ injections (separate anti-aging product, not a GLP-1)
- NAD+ wafers (separate anti-aging product, not a GLP-1)
Why consider it
- Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
- The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
- Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
Worth knowing
- The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
- Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
- Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
What customers say
Enhance.MD carries a solid 4.1/5 TrustScore on Trustpilot (rated "Great") with generally positive feedback on flat pricing, nurse-practitioner access and easy onboarding. The recurring criticisms are medication delays/cancellations without clear explanation, shipments arriving from different pharmacies, and inconsistent potency/efficacy of the compounded formulation between months.
Read customer evidence →Coverage & care
- Availability
- 40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WY. Not available in AL, AR, GA, HI, LA, MO, MS, ND, SC, TN. The FAQ says the company is licensed in all 50 states but that it is launching in the listed states only (verified 2026-09-03)
- Insurance
- Not accepted
- Consultation
- included
- Shipping
- free
The FAQ says you can pause or cancel your subscription at any time by contacting support, and that membership otherwise renews every 28 days. The 3, 6 and 12-month plans bill every 12, 24 and 48 weeks rather than monthly. Prescription products cannot be returned, and the only refund promised is 100% of the initial payment if a provider finds you ineligible during onboarding (verified 2026-09-03)
Independent research, not medical advice. Read our safety checks and sources.
All plans, payment and cancellation terms
- Consultation
- Included
- Shipping
- Free
- Insurance
- Not accepted
- Availability
- 40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WY. Not available in AL, AR, GA, HI, LA, MO, MS, ND, SC, TN. The FAQ says the company is licensed in all 50 states but that it is launching in the listed states only (verified 2026-09-03)
Cancellation and refunds: The FAQ says you can pause or cancel your subscription at any time by contacting support, and that membership otherwise renews every 28 days. The 3, 6 and 12-month plans bill every 12, 24 and 48 weeks rather than monthly. Prescription products cannot be returned, and the only refund promised is 100% of the initial payment if a provider finds you ineligible during onboarding (verified 2026-09-03)
Want the standalone record? Enhance MD pricing, every tier with verification dates and detected promotions.
All pricing tiers
Compounded Semaglutide (month-to-month)
$249 View details ↗Billed every 4 weeks; $50 off the first order with the on-page SUMMER50 code
Compounded Semaglutide (3-month plan)
$237 View details ↗Billed every 12 weeks; $100 off the first order with the on-page SUMMER100 code
Compounded Semaglutide (6-month plan)
$224 View details ↗Billed every 24 weeks; $100 off the first order with SUMMER100
Compounded Semaglutide (12-month plan)
$212 View details ↗Billed every 48 weeks; $100 off the first order with SUMMER100
Compounded Tirzepatide (first month)
$99 View details ↗Introductory first-month rate for compounded tirzepatide, as of the 2026-07-31 check; the tirzepatide product page was not re-scanned on 2026-08-28
Compounded Tirzepatide (ongoing)
$280 View details ↗Standard monthly rate for compounded tirzepatide
Elite Bundle (sema + tirz)
$322 View details ↗Combined semaglutide + tirzepatide bundle, $189 first month
Microdose Tirzepatide
$169 View details ↗Low-dose compounded tirzepatide for sensitive users or maintenance
NAD+ Therapy (subcutaneous)
$169 View details ↗NAD+ injection therapy, separate product line, not a GLP-1
Brand-Name GLP-1
$299 View details ↗FDA-approved Wegovy or Zepbound with basic clinical support
Why we reached this verdict
Enhance MD sells compounded GLP-1s only: semaglutide as GLP-1 Core, tirzepatide as GLP-1 Advanced, both in one formulation as GLP-1 Elite, and a capped 1mg microdosing tirzepatide plan. There is no brand-name option, and every product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines. Core is $212/mo on the 12-month plan billed every 48 weeks and $249/mo month to month, and that price does not rise as the dose does. Starting takes longer than a questionnaire: the published path is a medical intake form, a blood draw at a nearby Quest Diagnostics location covering a metabolic panel, TSH, lipids and HbA1c, then a scheduled video visit with a licensed provider, with metabolic lab testing every 6 months after that. Trustpilot rates it 4.1/5 across 132 reviews. Support is staffed seven days a week, and the FAQ puts availability at 40 states plus DC rather than nationwide (verified 2026-09-03).
What makes it different: The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.
Enhance MD Pros and Cons
What We Like
What We Like
- +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
- +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
- +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
- +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding
What Could Be Better
What Could Be Better
- −The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
- −Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
- −Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
- −Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)
Is Enhance MD legit? Pharmacy, prescribers and safety checks
Yes. Enhance MD is a real, operating telehealth company, and its third-party reviews are broadly positive. It holds 4.1 out of 5 across 132 Trustpilot reviews, and its BBB profile reads A+ (not accredited). It scores 7.8/10 on our methodology; the six signals below are how we checked.
Six trust signals, the evidence behind them, and what remains unverified.
Verification record for Enhance MD
Price checked .
Read individual claims alongside their dates and source links. A dated price check does not establish that every review detail was checked on the same day. Our editorial methodology explains the criteria.
Clinical evidence: 20.9% average body-weight reduction at 72 weeks in SURMOUNT-1 (NEJM, 2022). Individual results vary; compounded GLP-1s are not FDA-approved.
What the doctors say about GLP-1 medications
Independent, sourced clinical context on the medication class, not a comment on this provider.
“Thanks to the latest advancements in obesity management medications, more physicians and patients are witnessing significant weight reduction beyond what they have seen before. The SURMOUNT-5 head-to-head results demonstrated tirzepatide led to greater weight reduction compared to semaglutide, providing further evidence to support tirzepatide as an effective option for obesity.”
“Patients on both medications experienced substantial weight loss, and we observed no difference in the risk of gastrointestinal adverse events. In addition to effectiveness, factors like medication availability and insurance coverage will likely play a role in deciding which medication to initiate.”
Quotes are general medical commentary about GLP-1 medications, independently sourced and not solicited by GLP-1 Picks. They are not an endorsement of any provider, our provider scores are set solely by our published methodology.
Enhance MD reviews: what customers say
Recorded third-party ratings and source links for Enhance MD. “Not verified” means this review has no confirmed figure; it does not establish that no profile exists.
Enhance.MD carries a solid 4.1/5 TrustScore on Trustpilot (rated "Great") with generally positive feedback on flat pricing, nurse-practitioner access and easy onboarding. The recurring criticisms are medication delays/cancellations without clear explanation, shipments arriving from different pharmacies, and inconsistent potency/efficacy of the compounded formulation between months.
Reddit: Positive results reported (one user cited 98 lbs lost in 15 months) but recurring complaint that the compounded GLP-1 formulation feels less potent some months.
How Enhance MD works
Medical Intake
Complete a medical intake form covering your current lifestyle and medical history so a provider can build a treatment plan. The site says the form is quick and carries no charge.
Lab Work
Enhance.MD arranges a blood draw at a nearby Quest Diagnostics location covering a comprehensive metabolic panel, TSH, lipids and HbA1c. The site recommends fasting beforehand.
Virtual Visit
Once your lab results are back you are emailed a link to schedule a video consultation with a licensed provider, who assesses eligibility and decides whether a prescription is appropriate.
Monthly Delivery
Medication ships free from a partner pharmacy every 4 weeks on the GLP-1 plans, with metabolic lab testing every 6 months; the microdosing plan ships every 12 weeks.
Medications available
Common questions
Does Enhance MD sell Wegovy or Zepbound?+
Do I have to do a video visit and blood work?+
What does $212 a month actually buy?+
More questions (4)
Can I cancel, and what is refundable?+
What do verified reviews say about Enhance MD?+
Which GLP-1 medications does Enhance MD prescribe?+
Does Enhance MD take insurance?+
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Does Medicare Cover Wegovy or Ozempic for Weight Loss in 2026?
News & PipelineNext Weight Loss Drugs Pipeline (2026): Retatrutide 28.7%, CagriSema 22.7%, MariTide Monthly
Cost & InsuranceTirzepatide Cost 2026: $149 to $1,086/Month, Every Option Ranked (Verified July 2026)
Helpful Tools
Or jump to a specific program
Compounded tirzepatide (GLP-1 + GIP dual agonist). SURMOUNT-1's up-to-20.9% result studied the approved Zepbound formulation at trial doses and does not establish outcomes for this compounded product.
Premium tier with both compounded medications and switching flexibility.