Our Score

7.8/10

From$212/mo

TypeBoth

InsuranceNo

Rank#18 of 48

Brand-nameCompoundedUpdated April 2026

By Iacob Pastina · Independent Editor

Enhance MD GLP-1 Review

Name: Enhance MD GLP-1 Program
Brand: Enhance MD
Price: 212 USD
Availability: InStock
Rating: 7.8 (1 reviews)

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Independently researched. Every statistic links to a primary source (NEJM, JAMA, FDA, CMS, or the provider's official disclosures). Affiliate links do not influence scoring or recommendations. Last verified April 2026.

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Enhance MD scores 7.8/10 in our independent review, starting at $212/mo for brand-name and compounded GLP-1 medications. Enhance MD is the budget pick for users who want both medication types without paying $200+/mo. At $115/mo, it's one of the cheapest platforms offering brand-name and compounded options, and the combination therapy add-ons (B12, NAD+) are a nice differentiator.

What makes it different: The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.

At a glance

Get Enhance MD if

Budget-conscious users who still want medication variety
Experienced GLP-1 users transferring from another provider
Those interested in combination therapies (B12, NAD+ add-ons)

Skip if

First-time GLP-1 users who want structured clinical support
Those who need weekend customer support
Patients who prefer scheduled check-ins over self-directed care

Enhance MD Pros and Cons

What We Like

+$115/mo starting price with access to both brand-name and compounded — rare at this price point
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations — most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

What Could Be Better

−Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
−No insurance billing and limited customer support hours (business days only, no weekends)

What it costs

Headline pricing, full-year math, and how Enhance MD compares to the closest alternatives.

Quick facts

Monthly Cost

From $212/mo

Consultation

Included

Availability

All 50 States

Insurance

Not Accepted

Shipping

Free

Cancellation

Cancel anytime, no commitment

All pricing tiers

Compounded Semaglutide (first month)

$49/mo

Introductory first-month rate for compounded semaglutide

Compounded Semaglutide (ongoing)

$212/mo

Standard monthly rate for compounded semaglutide with async consultations and free shipping

Compounded Tirzepatide (first month)

$99/mo

Introductory first-month rate for compounded tirzepatide

Compounded Tirzepatide (ongoing)

$280/mo

Standard monthly rate for compounded tirzepatide

Elite Bundle (sema + tirz)

$322/mo

Combined semaglutide + tirzepatide bundle — $189 first month

Microdose Tirzepatide

$169/mo

Low-dose compounded tirzepatide for sensitive users or maintenance

NAD+ Therapy (subcutaneous)

$169/mo

NAD+ injection therapy — separate product line, not a GLP-1

Brand-Name GLP-1

$299/mo

FDA-approved Wegovy or Zepbound with basic clinical support

Cancellation policy: Cancel anytime, no commitment

How Enhance MD works

Online Questionnaire

Complete a health assessment in about 10 minutes. Choose your preferred medication type and any combination therapy add-ons you're interested in.

Async Provider Approval

A provider reviews your assessment asynchronously — no video call needed. Most patients are approved within 24 hours.

Self-Directed Treatment

Medication ships free. You manage your treatment through the portal, reaching out to your provider when you need dose adjustments or have questions.

Medications available

Semaglutide (compounded)Tirzepatide (compounded)WegovyZepboundSemaglutide + B12Semaglutide + NAD+

Ready to check Enhance MD's pricing for yourself?

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Is Enhance MD legit?

Six trust signals, how we checked them, and what's been updated since the last review.

Common questions

Questions readers ask about Enhance MD, similar providers to compare, and quick tools.

Frequently Asked Questions

What are the combination therapy options?+

Enhance MD offers compounded semaglutide with B12 (supports energy and metabolism) or NAD+ (supports cellular repair and energy). These are compounded into the same injection, not separate shots.

Why is it so much cheaper than other platforms?+

Enhance MD uses asynchronous consultations instead of video calls, has a lean support team, and negotiates aggressive pharmacy rates. The trade-off is less clinical hand-holding.

Can I switch from compounded to brand-name?+

Yes. Contact your provider through the portal to request a switch. Pricing changes to the brand-name tier, and the new prescription is typically processed within 48 hours.

How do dose adjustments work without scheduled check-ins?+

You initiate dose adjustment requests through the patient portal. Your provider reviews and approves changes, usually within 24 hours. It's self-directed but medically supervised.