MangoRx vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Yucca Health beats MangoRx overall, scoring 7.7/10 vs 7.5/10. Yucca Health is more affordable at $146/mo vs $299/mo. Choose MangoRx for users who want a multi-service telehealth platform covering . Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.
A side-by-side comparison of MangoRx and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
MangoRx
#27 of 46Multi-service telehealth platform offering compounded GLP-1 alongside other health services.
Visit MangoRxYucca Health
#19 of 46Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Visit Yucca Health| Feature | MangoRx | Yucca Health |
|---|---|---|
| Our Score | 7.5/10 | 7.7/10 |
| Starting Price | $299/mo | $146/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want a multi-service telehealth platform covering weight loss and men's health | Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments |
| Ranking | #27 | #19 |
Pros & Cons Compared
MangoRx
Pros
- +Oral dissolving tablets exclusively — zero injections for any GLP-1 option
- +Publicly traded on NASDAQ (MGRX) — SEC-required financial transparency that private competitors can't match
- +Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
- +Free 100% online consultation with no video call required
Cons
- −$299/mo for oral semaglutide is 2-3x the cost of injectable alternatives at $99-149/mo
- −Early-stage public company with limited revenue — stock performance reflects financial uncertainty
- −Only oral tablet format available — no injectable options if you want higher bioavailability
Yucca Health
Pros
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
Our Verdict
Yucca Health edges out MangoRx with a score of 7.7/10 vs 7.5/10. If budget is your priority, Yucca Health starts at $146/mo compared to MangoRx's $299/mo. Choose MangoRx if you want: users who want a multi-service telehealth platform covering weight loss and men's health. Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.