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Our Score
7.5/10
Headline pricefrom $299/mo
TypeCompounded
InsuranceNo
Rank#22 of 54
CompoundedUpdated August 14, 2026
By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

Researched against FDA labeling, published clinical-trial data (STEP-1 / SURMOUNT-1), and MangoRx's live pages, not a paid placement.

MangoRx logo

MangoRx GLP-1 Review

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

Bottom line

MangoRx owns a specific niche: oral-only GLP-1 with public-company accountability, and the NASDAQ listing is a genuine trust signal. Full verdict ↓

Independently researched. Every statistic links to a primary source (NEJM, JAMA, FDA, CMS, or the provider's official disclosures). Affiliate status never changes a provider's score; featured picks are affiliate partners, disclosed. Last verified May 17, 2026.

Clinical evidence: 20.9% average body-weight reduction at 72 weeks in SURMOUNT-1 (NEJM, 2022). Individual results vary; compounded GLP-1s are not FDA-approved.

Summarize this article with

MangoRx scores 7.5/10 in our independent review. Its headline semaglutide offer is from $299/mo. MangoRx is the rare oral-only GLP-1 platform: every option is a dissolving tablet, no injections whatsoever, and the semaglutide tablet includes Vitamin B6 to help with nausea. Being publicly traded (NASDAQ: MGRX) adds SEC-level transparency private competitors can't match.

What makes it different: Oral dissolving tablets exclusively (zero injections) from a publicly traded company (NASDAQ: MGRX) with SEC-level financial transparency.

At a glance

Get MangoRx if
  • Needle-phobic patients who want oral-only GLP-1 from a publicly traded company with regulatory transparency.
Skip if
  • Budget-conscious patients, $299/mo for oral semaglutide is 2-3x the cost of injectable alternatives.
Sounds like you? Visit MangoRx

MangoRx Pros and Cons

What We Like
  • +Oral dissolving tablets exclusively, zero injections for any GLP-1 option
  • +Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
  • +Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
  • +Free 100% online consultation with no video call required
What Could Be Better
  • Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
  • Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
  • Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.

What it costs

Headline pricing, full-year math, and how MangoRx compares to the closest alternatives.

Quick facts

Monthly Cost
Consultation
free
Availability
Select states (varies by regulation)
Insurance
Not Accepted
Shipping
Free
Cancellation
Not publicly disclosed

All pricing tiers

Slim (Oral Semaglutide + B6)

$299/mo

Monthly oral dissolving semaglutide tablet with Vitamin B6 for nausea reduction

Trim (Oral Tirzepatide)

$399/mo

Monthly oral dissolving tirzepatide tablet

Cancellation policy: Not publicly disclosed

MangoRx reviews: what customers say

What third-party review aggregators say about MangoRx. Cards show the verified primary metric only, “Not found” means no public profile surfaced in our verification pass.

Trustpilot
Not found
No public profile surfaced
BBB
Not found
No public profile surfaced
Reddit
Mixed sentiment
Aggregated from public threads
Provider claim
None disclosed
Our reading

MangoRx has a thin third-party review footprint: a real but tiny Trustpilot profile rating roughly 3.9/5 on only about 8 reviews, mostly tied to its older men's-health/TRT and ED lines rather than its new GLP-1 weight-loss products. Sentiment is mixed, some customers praise easy onboarding and helpful customer service, while at least one negative review calls the company a scam; there is essentially no independent GLP-1-specific patient feedback yet.

What people actually say

Reddit: Negligible Reddit footprint specific to MangoRx GLP-1; the company (NASDAQ: MGRX) only recently entered the GLP-1/weight-loss space, so there is no meaningful body of independent patient experience to read.

How MangoRx works

1

Free Online Consultation

Complete a 100% online consultation with a licensed medical professional, no video call required.

2

Physician Reviews Within 1-2 Days

A physician reviews your chart, questionnaire, and medical history within 1-2 business days.

3

Monthly Supply Ships Discreetly

If approved, your monthly supply of oral dissolving tablets ships discreetly to your door.

Medications available

Semaglutide (compounded oral dissolving tablet + B6)Tirzepatide (compounded oral dissolving tablet)

Ready to check MangoRx's pricing for yourself?

Visit MangoRx

MangoRx pharmacy, prescribers and safety checks

Six trust signals, how we checked them, and what's been updated since the last review.

Independent Clinical Perspective

What the doctors say about GLP-1 medications

Independent, sourced clinical context on the medication class, not a comment on this provider.

More options for people with these challenging diseases will be very helpful, particularly if the new oral tablet medicines are priced reasonably.
Daniel Drucker, MD, endocrinologist, co-discoverer of GLP-1's biological actions; 2025 Breakthrough Prize laureate
University of Toronto / Sinai Health
On head-to-head data for the oral GLP-1 pill orforglipron vs oral semaglutide.
People with overweight or obesity have individual preferences, and with oral semaglutide as a potential new treatment option, more of those who are not on treatment today may consider starting GLP-1 treatment.
Sean Wharton, MD, internal medicine physician; lead author, OASIS 4 trial
Wharton Medical Clinic
On the OASIS 4 results for oral semaglutide 25 mg (16.6% weight loss) as a pill alternative to injections.

Quotes are general medical commentary about GLP-1 medications, independently sourced and not solicited by GLP-1 Picks. They are not an endorsement of any provider, our provider scores are set solely by our published methodology.

Common questions

Questions readers ask about MangoRx, similar providers to compare, and quick tools.

Frequently Asked Questions

Are MangoRx medications injections?+
No. MangoRx exclusively offers oral dissolving tablets, no needles required for any of their GLP-1 options.
Why is MangoRx more expensive?+
Oral dissolving tablet formulations cost more to compound. The Slim tablet also includes Vitamin B6 to help reduce nausea.
Is MangoRx publicly traded?+
Yes. Mangoceuticals, Inc. trades on NASDAQ under ticker MGRX, providing SEC-required financial transparency.
Can I cancel MangoRx, and what are the terms?+
MangoRx states: Not publicly disclosed. Cancel before your next billing date rather than on it, and keep written confirmation.
Does MangoRx take insurance?+
No. MangoRx is cash pay only, so nothing is billed to a plan. On the listed price: consultation free, shipping included (discreet shipping).

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