MEDVi vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent research·How we rank →

MEDVi beats SynergyRx overall, scoring 7.7/10 vs 7.6/10. MEDVi is more affordable at $179/mo vs $199/mo. Choose MEDVi for users who want a low entry price with oral and injectable co. Choose SynergyRx for needle-phobic users who want oral dissolving tablets for sem.

A side-by-side look at MEDVi and SynergyRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

MEDVi

#20 of 52

7.7/10

MEDVi is a compounded GLP-1 telehealth platform offering both oral tablets and injectable semaglutide and tirzepatide, with micro-dosing options for side-effect-sensitive patients. $179/mo entry pricing, free shipping, and a streamlined intake, one of the broader compounded mixes among independent telehealth providers in 2026.

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SynergyRx

#22 of 52

7.6/10

Bundled GLP-1 program with predictable pricing and round-the-clock support access for peace of mind.

Visit SynergyRx

Feature	MEDVi	SynergyRx
Our Score	7.7/10	7.6/10
Starting Price	$179/mo	$199/mo
Medication Type	Both	Both
Insurance Accepted	No	No
Best For	Users who want a low entry price with oral and injectable compounded options	Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included
Ranking	#20	#22
Get started	Visit MEDVi	Visit SynergyRx

Pros & Cons Compared

MEDVi

Pros

+One of the few compounded providers offering both oral tablets and injectable semaglutide
+Micro-dosing options available, can start at sub-standard doses for patients concerned about side effects
+Sleek onboarding experience with clear progress tracking through their patient portal
+$179/mo is competitive for a platform with both oral and injectable compounded formulations

Cons

−No brand-name Wegovy or Zepbound on the platform (the 2026 expansion added branded Ozempic only)
−No insurance accepted, and oral compounded semaglutide has less clinical data than injectable forms; you can switch to injectable anytime at no extra fee if results lag

SynergyRx

Pros

+Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
+Free expedited shipping included with all orders
+24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
+Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

−Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
−Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
−Company history, founding date, and ownership structure are not publicly disclosed. Ask support for pharmacy and prescriber details upfront.

Our Verdict

MEDVi edges out SynergyRx with a score of 7.7/10 vs 7.6/10. If budget is your priority, MEDVi starts at $179/mo compared to SynergyRx's $199/mo. Choose MEDVi if you want: users who want a low entry price with oral and injectable compounded options. Choose SynergyRx if you want: needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither MEDVi nor SynergyRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Visit Yucca Health→Read our full Yucca Health review