SkinnyRx vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Yucca Health beats SkinnyRx overall, scoring 7.7/10 vs 7.3/10. Yucca Health is more affordable at $146/mo vs $199/mo. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.
A side-by-side comparison of SkinnyRx and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
SkinnyRx
#36 of 47Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats — injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only — does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRxYucca Health
#19 of 47Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Visit Yucca Health| Feature | SkinnyRx | Yucca Health |
|---|---|---|
| Our Score | 7.3/10 | 7.7/10 |
| Starting Price | $199/mo | $146/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point | Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments |
| Ranking | #36 | #19 |
Pros & Cons Compared
SkinnyRx
Pros
- +Five medication formats — the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
- +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
- +Fast onboarding: 5–10 minute online questionnaire, physician review in 24–48 hours, medication delivered in 3–7 business days with temperature-controlled shipping
- +4,100+ Trustpilot reviews at 4.8 stars — among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded-only model limits patients who want or need an FDA-approved finished product
- −Limited public transparency: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site
- −Cash-pay only — does not bill commercial insurance, Medicare, or Medicaid (HSA/FSA payments accepted)
- −Independent reviews flag inconsistent customer-service responsiveness, which is a real concern for a medication that requires titration support and dose-adjustment dialogue
Yucca Health
Pros
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
Our Verdict
Yucca Health edges out SkinnyRx with a score of 7.7/10 vs 7.3/10. If budget is your priority, Yucca Health starts at $146/mo compared to SkinnyRx's $199/mo. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point. Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.