SkinnyRx vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Yucca Health beats SkinnyRx overall, scoring 7.7/10 vs 7.3/10. Yucca Health is more affordable at $146/mo vs $199/mo. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want nam.
A side-by-side comparison of SkinnyRx and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
SkinnyRx
#36 of 49Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats — injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only — does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRxYucca Health
#19 of 49Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors — Dr. Michael Wasef MD and Dr. Andrew Sakla DO — handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.
Visit Yucca Health| Feature | SkinnyRx | Yucca Health |
|---|---|---|
| Our Score | 7.3/10 | 7.7/10 |
| Starting Price | $199/mo | $146/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point | People who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay) |
| Ranking | #36 | #19 |
Pros & Cons Compared
SkinnyRx
Pros
- +Five medication formats — the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
- +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
- +Fast onboarding: 5–10 minute online questionnaire, physician review in 24–48 hours, medication delivered in 3–7 business days with temperature-controlled shipping
- +4,100+ Trustpilot reviews at 4.8 stars — among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded-only model limits patients who want or need an FDA-approved finished product
- −Limited public transparency: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site
- −Cash-pay only — does not bill commercial insurance, Medicare, or Medicaid (HSA/FSA payments accepted)
- −Independent reviews flag inconsistent customer-service responsiveness, which is a real concern for a medication that requires titration support and dose-adjustment dialogue
Yucca Health
Pros
- +Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — most compounded GLP-1 providers don't publicly name their prescribers.
- +4.6 stars across 1,065 verified Trustpilot reviews — 84% give 5 stars. Top complimented theme: customer service.
- +Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
- +Buy-now-pay-later through Klarna, Affirm, and Afterpay — unusual flexibility in this category, useful for spreading the 6-month upfront cost.
- +24-hour async approval — no live video visit required. Faster onboarding than competitors that need a scheduled call.
- +UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
- +Replies to 100% of negative Trustpilot reviews, usually within 48 hours.
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
- −The $146/mo price requires a 6-month upfront commitment. Month-to-month is meaningfully more expensive.
- −No live tele-visit option — only async review. Faster, but less depth if you have a complex health history.
- −Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
- −Founders and detailed company history not on the site.
- −Refund policy is mentioned but not detailed publicly — verify the cancellation terms before paying for the 6-month plan.
Our Verdict
Yucca Health edges out SkinnyRx with a score of 7.7/10 vs 7.3/10. If budget is your priority, Yucca Health starts at $146/mo compared to SkinnyRx's $199/mo. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point. Choose Yucca Health if you want: people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).
Read Full Reviews
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