Fridays vs MyStart Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Fridays scores higher on our rubric, 8.7/10 against 7.7/10. Full reasoning, pricing and the cases where the other one wins are below.

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Fridays beats MyStart Health overall, scoring 8.7/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Fridays is $249/mo month-to-month; MyStart Health is from $299/mo. Choose Fridays for users who want a holistic program with coaching, nutrition support, and flexible pricing. Choose MyStart Health for users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee.

A side-by-side look at Fridays and MyStart Health to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Fridays

#1 of 54

8.7/10

Holistic weight loss program combining GLP-1 medications with lifestyle coaching, nutrition guidance, and ongoing support.

Visit Fridays

MyStart Health

#17 of 54

7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health

Feature	Fridays	MyStart Health
Why each one	One of the only GLP-1 platforms that combines direct insurance billing with integrated nutrition coaching, making it both the most affordable (with insurance) and most comprehensive option.	Price Lock Guarantee ensures your monthly rate never increases even as your dose escalates, plus access to 600+ board-certified doctors.
Our Score	8.7/10	7.7/10
Headline Price	$249/mo month-to-month	from $299/mo
Medication Type	Both	Compounded
Insurance Accepted	Yes	No
Best For	Users who want a holistic program with coaching, nutrition support, and flexible pricing	Users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee
Watch out for	The coaching-heavy model adds complexity, three different plan tiers with different inclusions	Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
Ranking	#1	#17
Get started	Visit Fridays	Visit MyStart Health

Pros & Cons Compared

Fridays

Pros

+One of the few platforms that bills insurance directly, can reduce out-of-pocket to $25-50/mo with coverage
+Includes 1-on-1 nutrition coaching and weekly check-ins, not just medication prescriptions
+Offers brand-name Wegovy/Zepbound and compounded options, switches based on insurance formulary
+Flexible plans: medication-only ($249/mo) or full coaching program ($299/mo)

Cons

−The coaching-heavy model adds complexity, three different plan tiers with different inclusions
−Without insurance, $249/mo for medication-only is above average for what you get clinically

MyStart Health

Pros

+Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
+Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
+Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
+HSA/FSA eligible, can use pre-tax health savings to pay for treatment

Cons

−Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
−Select states only, not all 50, and the exact list isn't published. Confirm your state during the intake quiz before paying
−Compounded medications only, no brand-name GLP-1 option on the menu

Our Verdict

Fridays edges out MyStart Health with a score of 8.7/10 vs 7.7/10. Published pricing is not a like-for-like monthly comparison: Fridays is $249/mo month-to-month; MyStart Health is from $299/mo. Fridays accepts insurance, which can significantly reduce your out-of-pocket costs. Fridays offers both brand-name and compounded medications, giving you more flexibility.