Fridays vs MyStart Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

Fridays beats MyStart Health overall, scoring 8.7/10 vs 7.7/10. Fridays is more affordable at $249/mo vs $299/mo. Choose Fridays for users who want a holistic program with coaching, nutrition s. Choose MyStart Health for users who want a monthly price that stays locked as their do.

A side-by-side look at Fridays and MyStart Health to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Fridays

#2 of 52
8.7/10

Holistic weight loss program combining GLP-1 medications with lifestyle coaching, nutrition guidance, and ongoing support.

Visit Fridays

MyStart Health

#21 of 52
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health
FeatureFridaysMyStart Health
Our Score8.7/107.7/10
Starting Price$249/mo$299/mo
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want a holistic program with coaching, nutrition support, and flexible pricingUsers who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee
Ranking#2#21
Get startedVisit FridaysVisit MyStart Health

Pros & Cons Compared

Fridays

Pros

  • +One of the few platforms that bills insurance directly, can reduce out-of-pocket to $25-50/mo with coverage
  • +Includes 1-on-1 nutrition coaching and weekly check-ins, not just medication prescriptions
  • +Offers brand-name Wegovy/Zepbound and compounded options, switches based on insurance formulary
  • +Flexible plans: medication-only ($249/mo) or full coaching program ($299/mo)

Cons

  • The coaching-heavy model adds complexity, three different plan tiers with different inclusions
  • Without insurance, $249/mo for medication-only is above average for what you get clinically

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +HSA/FSA eligible, can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
  • Select states only, not all 50, and the exact list isn't published. Confirm your state during the intake quiz before paying
  • Compounded medications only, no brand-name GLP-1 option on the menu

Our Verdict

Fridays edges out MyStart Health with a score of 8.7/10 vs 7.7/10. If budget is your priority, Fridays starts at $249/mo compared to MyStart Health's $299/mo. Fridays accepts insurance, which can significantly reduce your out-of-pocket costs. Fridays offers both brand-name and compounded medications, giving you more flexibility. Choose Fridays if you want: users who want a holistic program with coaching, nutrition support, and flexible pricing. Choose MyStart Health if you want: users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither Fridays nor MyStart Health feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try Fridays

Starting at $249/mo

Visit Fridays

Try MyStart Health

Starting at $299/mo

Visit MyStart Health

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.