Hone Health vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 7.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats Hone Health overall, scoring 7.8/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: Hone Health is from $309/mo; TMates is from $158/mo. Choose Hone Health for users who want a full-service health platform covering weight loss plus hormones and labs. Choose TMates for users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

A side-by-side look at Hone Health and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Hone Health

#33 of 54

7.3/10

Comprehensive men's health platform that includes GLP-1 medications alongside hormone optimization and lab testing.

Visit Hone Health

Higher Rated

TMates

#11 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

Visit TMates

Feature	Hone Health	TMates
Why each one	Longevity-first platform with 40+ biomarker lab panels, goes beyond weight loss into comprehensive health optimization.	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
Our Score	7.3/10	7.8/10
Headline Price	from $309/mo	from $158/mo
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Users who want a full-service health platform covering weight loss plus hormones and labs	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out for	Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive options	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
Ranking	#33	#11
Get started	Visit Hone Health	Visit TMates

Pros & Cons Compared

Hone Health

Pros

+40+ biomarker lab panel included, the most comprehensive baseline testing of any GLP-1 telehealth provider
+Full health optimization platform covering hormones, longevity, and metabolic health beyond just weight loss
+Starts patients on gentler liraglutide before escalating, reduces first-week side effect severity
+Both compounded and potentially brand-name GLP-1 options available depending on clinical assessment

Cons

−Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive options
−Select state availability, not available nationwide, and coverage varies by specific treatment program
−The $149/mo membership fee is required even before you can purchase any medication

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out Hone Health with a score of 7.8/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: Hone Health is from $309/mo; TMates is from $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.