MyStart Health vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

TrimRx beats MyStart Health overall, scoring 7.8/10 vs 7.7/10. TrimRx is more affordable at $149/mo vs $299/mo. Choose MyStart Health for users who want a monthly price that stays locked as their do. Choose TrimRx for users who want affordable compounded semaglutide at one flat.

A side-by-side look at MyStart Health and TrimRx to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

MyStart Health

#21 of 52
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health
Higher Rated

TrimRx

#11 of 52
7.8/10

Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.

Visit TrimRx
FeatureMyStart HealthTrimRx
Our Score7.7/107.8/10
Starting Price$299/mo$149/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guaranteeUsers who want affordable compounded semaglutide at one flat, all-inclusive price
Ranking#21#11
Get startedVisit MyStart HealthVisit TrimRx

Pros & Cons Compared

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +HSA/FSA eligible, can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
  • Select states only, not all 50, and the exact list isn't published. Confirm your state during the intake quiz before paying
  • Compounded medications only, no brand-name GLP-1 option on the menu

TrimRx

Pros

  • +$149/mo all-inclusive for compounded semaglutide, one of the lowest prices for a full-service program
  • +Onboarding takes under 15 minutes with same-day provider review for most applications
  • +Free medication replacement if your shipment is lost or damaged in transit

Cons

  • Compounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.
  • No insurance billing and no superbill for out-of-network reimbursement, so treat the $149/mo as a pure cash-pay price

Our Verdict

TrimRx edges out MyStart Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, TrimRx starts at $149/mo compared to MyStart Health's $299/mo. Choose MyStart Health if you want: users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee. Choose TrimRx if you want: users who want affordable compounded semaglutide at one flat, all-inclusive price.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither MyStart Health nor TrimRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try MyStart Health

Starting at $299/mo

Visit MyStart Health

Try TrimRx

Starting at $149/mo

Visit TrimRx

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.