Enhance MD vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Enhance MD - our pick of these two →or find your match

Enhance MD beats TrimRx overall, scoring 7.8/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; TrimRx is published $179/mo; total not verified. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose TrimRx for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

A side-by-side look at Enhance MD and TrimRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Enhance MD

#13 of 54

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Visit Enhance MD

TrimRx

#47 of 54

5.3/10

Cash-pay compounded GLP-1 provider offering semaglutide and a dual-agonist option it labels 'GLP-1 + GIP.' Its landing advertises a $179 floor, while its terms list semaglutide at $199 for the first order and $299 for follow-ups, and GLP-1 + GIP at $349 then $399. That conflict, plus a corroborated billing and fulfillment complaint pattern, is central to our 5.3/10 score.

Visit TrimRx

Feature	Enhance MD	TrimRx
Why each one	The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.	A written lost-or-damaged shipment replacement promise and both compounded molecule classes through one intake; neither resolves the first-party price conflict or fulfillment record.
Our Score	7.8/10	5.3/10
Headline Price	from $212/mo	published $179/mo; total not verified
Medication Type	Both	Compounded
Insurance Accepted	No	No
Best For	Budget-conscious users interested in combination therapies	Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment
Watch out for	Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence	The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
Ranking	#13	#47
Get started	Visit Enhance MD	Visit TrimRx

Pros & Cons Compared

Enhance MD

Pros

+GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations, most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
−No insurance billing, and customer support runs business days only, no weekends

TrimRx

Pros

+Offers both compounded semaglutide and a compounded GLP-1 + GIP option through one intake
+The landing advertises a $179 entry floor, although that figure does not match the medication schedule in the official terms
+Onboarding takes under 15 minutes with same-day provider review for most applications
+Free medication replacement if your shipment is lost or damaged in transit

Cons

−The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
−Trustpilot is 3.6/5 across 5,485 reviews with 32% one-star; BBB rates TrimRx F/not accredited with 728 unanswered and 221 unresolved complaints
−The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold
−Compounded only, no brand-name Wegovy or Zepbound. Compounded drugs are not FDA-approved finished products.
−No insurance billing and no superbill for out-of-network reimbursement, so treat the monthly price as a pure cash-pay number

Our Verdict

Enhance MD edges out TrimRx with a score of 7.8/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; TrimRx is published $179/mo; total not verified. Enhance MD offers both brand-name and compounded medications, giving you more flexibility.