MyStart Health vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Willow beats MyStart Health overall, scoring 8.2/10 vs 7.7/10. Choose MyStart Health for users who value a money-back weight-loss guarantee and price. Choose Willow for users who want comprehensive clinical support with flexibili.

A side-by-side comparison of MyStart Health and Willow covering pricing, scores, medication types, insurance, and more to help you decide.

MyStart Health

#23 of 48

7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

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Higher Rated

Willow

#8 of 48

8.2/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only — Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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Feature	MyStart Health	Willow
Our Score	7.7/10	8.2/10
Starting Price	$299/mo	$299/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Users who value a money-back weight-loss guarantee and price-lock protection	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Ranking	#23	#8

Pros & Cons Compared

MyStart Health

Pros

+Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates — a genuine differentiator
+Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
+Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
+HSA/FSA eligible — can use pre-tax health savings to pay for treatment

Cons

−Cash-pay only — no insurance accepted, which limits options for patients with GLP-1 coverage
−Only available in select states — not all 50, and the exact state list isn't published
−Compounded medications only — no brand-name GLP-1 options available

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide — one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only — no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses — starting dose is $399/mo
−Cash-pay only — no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024 — less track record than Ro or Hims, though growth has been fast

Our Verdict

Willow edges out MyStart Health with a score of 8.2/10 vs 7.7/10. Choose MyStart Health if you want: users who value a money-back weight-loss guarantee and price-lock protection. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither MyStart Health nor Willow feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review