MyStart Health vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

MyStart Health beats Willow overall, scoring 7.7/10 vs 7.5/10. Choose MyStart Health for users who want a monthly price that stays locked as their do. Choose Willow for users who want comprehensive clinical support with flexibili.

A side-by-side look at MyStart Health and Willow to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

MyStart Health

#21 of 52
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health

Willow

#24 of 52
7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

Visit Willow
FeatureMyStart HealthWillow
Our Score7.7/107.5/10
Starting Price$299/mo$299/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guaranteeUsers who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Ranking#21#24
Get startedVisit MyStart HealthVisit Willow

Pros & Cons Compared

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +HSA/FSA eligible, can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only, no insurance accepted. If your plan covers GLP-1s, price that route first; HSA/FSA cards do work here
  • Select states only, not all 50, and the exact list isn't published. Confirm your state during the intake quiz before paying
  • Compounded medications only, no brand-name GLP-1 option on the menu

Willow

Pros

  • +Includes monthly provider check-ins and dose adjustments at no extra cost
  • +Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
  • +$299/mo all-in for compounded semaglutide with monthly provider support
  • +90%+ patient retention rate after 3 months per their published outcomes data

Cons

  • Compounded-only, no brand-name Wegovy or Zepbound through the platform
  • Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
  • Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
  • Founded in 2024, less track record than Ro or Hims, though growth has been fast

Our Verdict

MyStart Health edges out Willow with a score of 7.7/10 vs 7.5/10. Choose MyStart Health if you want: users who want a monthly price that stays locked as their dose increases, backed by a money-back weight-loss guarantee. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither MyStart Health nor Willow feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try MyStart Health

Starting at $299/mo

Visit MyStart Health

Try Willow

Starting at $299/mo

Visit Willow

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.