TMates vs Yucca Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
TMates beats Yucca Health overall, scoring 7.8/10 vs 7.7/10. Yucca Health is more affordable at $146/mo vs $158/mo. Choose TMates for users who want flexible pricing across compounded glp-1s (me. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.
A side-by-side comparison of TMates and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.
TMates
#16 of 46Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.
Visit TMatesYucca Health
#19 of 46Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.
Visit Yucca Health| Feature | TMates | Yucca Health |
|---|---|---|
| Our Score | 7.8/10 | 7.7/10 |
| Starting Price | $158/mo | $146/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want flexible pricing across compounded GLP-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand Wegovy or Zepbound ($99/mo, patient fills at own pharmacy) | Cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments |
| Ranking | #16 | #19 |
Pros & Cons Compared
TMates
Pros
- +Steep multi-month commitment discounts on compounded sema — $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
- +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo — prescription goes to patient's pharmacy (you fill separately using insurance or cash)
- +Same price at all dose levels for compounded — no cost escalation as you titrate up
- +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach
Cons
- −Brand Wegovy/Zepbound $99/mo is CLINICAL SERVICE ONLY — medication cost is separate (paid at your pharmacy, which can be $1,000+/mo cash without insurance)
- −Best compounded pricing requires 6-12 month prepayment (upfront $1,050-$1,900)
- −90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
- −Not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound) — TMates prescribes but does not dispense brand-name
Yucca Health
Pros
- +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
- +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
- +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
- +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
- +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
- +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)
Cons
- −Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
- −Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
- −No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
- −Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
- −B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
- −Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan
Our Verdict
TMates edges out Yucca Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, Yucca Health starts at $146/mo compared to TMates's $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility. Choose TMates if you want: users who want flexible pricing across compounded glp-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand wegovy or zepbound ($99/mo, patient fills at own pharmacy). Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.