Willow vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Willow beats Yucca Health overall, scoring 8.2/10 vs 7.7/10. Yucca Health is more affordable at $146/mo vs $299/mo. Choose Willow for users who want comprehensive clinical support with flexibili. Choose Yucca Health for cash-pay patients who want a quick 24-hour async approval fo.

A side-by-side comparison of Willow and Yucca Health covering pricing, scores, medication types, insurance, and more to help you decide.

Higher Rated

Willow

#8 of 46
8.2/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only — Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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Yucca Health

#19 of 46
7.7/10

Telehealth platform for compounded semaglutide+ and tirzepatide+ with disclosed board-certified prescribers (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), 24-hour asynchronous provider review, UPS 2-Day Air shipping, and integrated buy-now-pay-later financing through Klarna, Affirm, and Afterpay. Pricing is plan-length-tiered: 6-month plan starts at $146/mo for compounded semaglutide and $258/mo for compounded tirzepatide, with monthly pricing higher.

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FeatureWillowYucca Health
Our Score8.2/107.7/10
Starting Price$299/mo$146/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routesCash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, UPS 2-Day shipping, and Klarna/Affirm/Afterpay buy-now-pay-later options on longer commitments
Ranking#8#19

Pros & Cons Compared

Willow

Pros

  • +Includes monthly provider check-ins and dose adjustments at no extra cost
  • +Offers both injectable AND oral compounded semaglutide — one of few platforms with a daily oral tablet option
  • +$299/mo all-in for compounded semaglutide with monthly provider support
  • +90%+ patient retention rate after 3 months per their published outcomes data

Cons

  • Compounded-only — no brand-name Wegovy or Zepbound through the platform
  • Tirzepatide pricing reaches $499-$524 at higher doses — starting dose is $399/mo
  • Cash-pay only — no insurance billing, though they provide superbills for FSA/HSA
  • Founded in 2024 — less track record than Ro or Hims, though growth has been fast

Yucca Health

Pros

  • +Two named board-certified prescribers publicly disclosed (Dr. Michael Wasef MD and Dr. Andrew Sakla DO) — rare for the compounded-only tier
  • +$146/mo entry price for compounded semaglutide on the 6-month plan is competitive with GobyMeds, Strut, and Mochi at the cheaper end of the market
  • +Klarna, Affirm, and Afterpay buy-now-pay-later financing on the 6-month commitments — unique among compounded-only telehealth and useful for spreading the upfront cost
  • +24-hour asynchronous provider approval (no live tele-visit required) for users who want fast onboarding without scheduling friction
  • +UPS 2-Day Air shipping with secure patient portal, 24/7 support team availability, and welcome onboarding call with a representative
  • +Trustpilot 4.4-star rating across 1,000+ reviews and 4.8-star Google rating signal real-world adoption (20,000+ patients reported, 1,000+ enrollments in last 7 days per their site)

Cons

  • Compounded-only — no FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro, or Foundayo; no oral semaglutide tablet or sublingual format
  • Best pricing requires 6-month commitment (BNPL helps but the discount tier is locked to longer plans — month-to-month is materially higher)
  • No live tele-visit option in the standard intake — purely asynchronous review, which trades clinical depth for speed
  • Founding year, corporate headquarters city, and compounding pharmacy partner names are not publicly disclosed
  • B12 supplementation is not part of the standard formulation (some competitors like PeterMD include it; Yucca markets the products as 'Semaglutide+' and 'Tirzepatide+' but does not specify what the '+' represents)
  • Refund policy referenced on the site but not detailed in public-facing terms — verify before paying for the 6-month plan

Our Verdict

Willow edges out Yucca Health with a score of 8.2/10 vs 7.7/10. If budget is your priority, Yucca Health starts at $146/mo compared to Willow's $299/mo. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes. Choose Yucca Health if you want: cash-pay patients who want a quick 24-hour async approval for compounded semaglutide or tirzepatide with disclosed prescribing physicians, ups 2-day shipping, and klarna/affirm/afterpay buy-now-pay-later options on longer commitments.

Try Willow

Starting at $299/mo

Visit Willow

Try Yucca Health

Starting at $146/mo

Visit Yucca Health
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Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

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