AgelessRx vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 7.0/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats AgelessRx overall, scoring 7.8/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; TMates is from $158/mo. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging treatments. Choose TMates for users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

A side-by-side look at AgelessRx and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

AgelessRx

#40 of 54

7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

Visit AgelessRx

Higher Rated

TMates

#11 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

Visit TMates

Feature	AgelessRx	TMates
Why each one	Longevity medicine pioneer offering GLP-1 microdosing alongside anti-aging treatments (NAD+, metformin, rapamycin), no membership fee required.	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
Our Score	7/10	7.8/10
Headline Price	from $199/mo + $50/mo clinical oversight	from $158/mo
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Longevity-minded users who want GLP-1 alongside anti-aging treatments	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out for	$50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/mo	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
Ranking	#40	#11
Get started	Visit AgelessRx	Visit TMates

Pros & Cons Compared

AgelessRx

Pros

+No membership fee, pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
+GLP-1 microdosing protocols available from $79/mo, one of only two platforms offering sub-therapeutic doses for metabolic health
+Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
+Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

−$50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/mo
−Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
−Cold-shipping limitations may affect availability in Alaska and Hawaii

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out AgelessRx with a score of 7.8/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; TMates is from $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs.