AgelessRx vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent research·How we rank →

TMates beats AgelessRx overall, scoring 7.8/10 vs 7/10. AgelessRx is more affordable at $139/mo vs $158/mo. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging t. Choose TMates for users who want commitment-discount pricing on compounded glp.

A side-by-side look at AgelessRx and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

AgelessRx

#46 of 52

7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

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Higher Rated

TMates

#14 of 52

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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Feature	AgelessRx	TMates
Our Score	7/10	7.8/10
Starting Price	$139/mo	$158/mo
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Longevity-minded users who want GLP-1 alongside anti-aging treatments	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Ranking	#46	#14
Get started	Visit AgelessRx	Visit TMates

Pros & Cons Compared

AgelessRx

Pros

+No membership fee, pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
+GLP-1 microdosing protocols available from $79/mo, one of only two platforms offering sub-therapeutic doses for metabolic health
+Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
+Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

−$50/mo clinical oversight fee on top of medication cost, semaglutide totals ~$340/mo, making it one of the pricier options
−Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
−Cold-shipping limitations may affect availability in Alaska and Hawaii

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out AgelessRx with a score of 7.8/10 vs 7/10. If budget is your priority, AgelessRx starts at $139/mo compared to TMates's $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. Choose AgelessRx if you want: longevity-minded users who want glp-1 alongside anti-aging treatments. Choose TMates if you want: users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither AgelessRx nor TMates feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Visit Yucca Health→Read our full Yucca Health review