Calibrate vs HealthRX: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent researchHow we rank →

Calibrate beats HealthRX overall, scoring 7.7/10 vs 5.2/10. HealthRX is more affordable at $99/mo vs $199/mo. Choose Calibrate for users who want a physician-led metabolic health program with. Choose HealthRX for cash-pay patients who want low flat-dose compounded glp-1 pr.

A side-by-side look at Calibrate and HealthRX to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Calibrate

#19 of 53
7.7/10

Metabolic health company offering a physician-led GLP-1 program restructured in 2026: $199/mo with a 3-month minimum commitment (no more $1,649 one-time enrollment fee). Includes nutrition coaching, labs, a smart scale, and a 10%+ weight-loss guarantee with 50% money-back.

Visit Calibrate

HealthRX

#50 of 53
5.2/10

HealthRX is a cash-pay telehealth platform for compounded injectable semaglutide and tirzepatide. Its July 2026 landing page lists semaglutide at $133/mo on a 3-month plan or $99/mo on a 12-month plan, plus tirzepatide at $209/mo or $179/mo. Prices stay flat across doses and include clinician review, dose adjustments, and overnight shipping. MD Integrations supplies the clinician network, while the dispensing 503A pharmacy remains unnamed on the public site.

Visit HealthRX
FeatureCalibrateHealthRX
Our Score7.7/105.2/10
Starting Price$199/mo$99/mo
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guaranteeCash-pay patients who want low flat-dose compounded GLP-1 pricing, all-50-state access, fast shipping, and self-service cancellation
Ranking#19#50
Get startedVisit CalibrateVisit HealthRX

Pros & Cons Compared

Calibrate

Pros

  • +2026 pricing rewrite, flat $199/mo with 3-month commitment ($597 upfront), then month-to-month. The old $1,649 one-time enrollment fee was removed.
  • +Board-certified physicians with metabolic health specialization lead treatment
  • +10%+ body-weight-loss guarantee with 50% money-back if not met
  • +Includes labs, nutrition coaching, personalized smart scale, and sleep/exercise support

Cons

  • $597 upfront (3-month commitment) is a meaningful barrier vs. month-to-month competitors
  • Medication cost is separate and varies significantly by payer route
  • Fewer medications in the menu than larger marketplaces like Ro or Found
  • Onboarding still takes 2-3 weeks to complete baseline labs and treatment plan

HealthRX

Pros

  • +$99/mo compounded semaglutide on the 12-month plan, with a $133/mo 3-month option
  • +Flat pricing across doses, clinician review, dose adjustments, and overnight shipping included
  • +Licensed clinicians in all 50 states through MD Integrations, with most files reviewed within about 24 hours
  • +LegitScript certificate 50087439 links to the issuer's verification checker
  • +Single-click account cancellation and refunds for unshipped doses
  • +Published HIPAA notice, telehealth consent, safety information, and emergency instructions

Cons

  • The dispensing 503A pharmacy is described by type while its name and license remain absent from the public site
  • Legal entity, headquarters, executive team, and medical director remain undisclosed
  • The tirzepatide product page advertises $149/mo while the current affiliate landing and FAQ say $179/mo, so confirm the checkout rate
  • The 4.8/5 from 12,000+ members block uses illustrative composites rather than an independent review platform
  • Cash-pay only, with no insurance billing or prior-authorization support
  • Compounded medications sit outside FDA premarket approval as finished products

Our Verdict

Calibrate edges out HealthRX with a score of 7.7/10 vs 5.2/10. If budget is your priority, HealthRX starts at $99/mo compared to Calibrate's $199/mo. Calibrate accepts insurance, which can significantly reduce your out-of-pocket costs. Calibrate offers both brand-name and compounded medications, giving you more flexibility. Choose Calibrate if you want: users who want a physician-led metabolic health program with a 3-month commitment and a weight-loss guarantee. Choose HealthRX if you want: cash-pay patients who want low flat-dose compounded glp-1 pricing, all-50-state access, fast shipping, and self-service cancellation.

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither Calibrate nor HealthRX feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Try Calibrate

Starting at $199/mo

Visit Calibrate

Try HealthRX

Starting at $99/mo

Visit HealthRX

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

TrimRx

7.8/10
$149/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

Embody

7.3/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.