Enhance MD vs Hone Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 7.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Enhance MD - our pick of these two →or find your match

Enhance MD beats Hone Health overall, scoring 7.8/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Hone Health is from $309/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Hone Health for users who want a full-service health platform covering weight loss plus hormones and labs.

A side-by-side look at Enhance MD and Hone Health to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

Enhance MD

#13 of 54

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Visit Enhance MD

Hone Health

#33 of 54

7.3/10

Comprehensive men's health platform that includes GLP-1 medications alongside hormone optimization and lab testing.

Visit Hone Health

Feature	Enhance MD	Hone Health
Why each one	The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.	Longevity-first platform with 40+ biomarker lab panels, goes beyond weight loss into comprehensive health optimization.
Our Score	7.8/10	7.3/10
Headline Price	from $212/mo	from $309/mo
Medication Type	Both	Compounded
Insurance Accepted	No	No
Best For	Budget-conscious users interested in combination therapies	Users who want a full-service health platform covering weight loss plus hormones and labs
Watch out for	Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence	Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive options
Ranking	#13	#33
Get started	Visit Enhance MD	Visit Hone Health

Pros & Cons Compared

Enhance MD

Pros

+GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations, most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
−No insurance billing, and customer support runs business days only, no weekends

Hone Health

Pros

+40+ biomarker lab panel included, the most comprehensive baseline testing of any GLP-1 telehealth provider
+Full health optimization platform covering hormones, longevity, and metabolic health beyond just weight loss
+Starts patients on gentler liraglutide before escalating, reduces first-week side effect severity
+Both compounded and potentially brand-name GLP-1 options available depending on clinical assessment

Cons

−Layered pricing: $65 initial consult + $149/mo membership + medication cost = $300-650/mo total, one of the most expensive options
−Select state availability, not available nationwide, and coverage varies by specific treatment program
−The $149/mo membership fee is required even before you can purchase any medication

Our Verdict

Enhance MD edges out Hone Health with a score of 7.8/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Hone Health is from $309/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility.