Enhance MD vs MyStart Health: Which GLP-1 Provider Is Better?
Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 5.7/10. Full reasoning, pricing and the cases where the other one wins are below.
Enhance MD beats MyStart Health overall, scoring 7.8/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; MyStart Health is from $299/mo. Choose Enhance MD for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it. Choose MyStart Health for users who want a monthly price that stays locked as their dose increases, and who can live with a policy that refunds nothing once medication ships.
A side-by-side look at Enhance MD and MyStart Health to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Enhance MD
#12 of 54Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).
Visit Enhance MDMyStart Health
#43 of 54GLP-1 provider whose Price Lock Guarantee holds your monthly rate flat as your dose escalates, on an all-inclusive program that starts at $299 a month on its homepage FAQ.
Visit MyStart Health| Feature | Enhance MD | MyStart Health |
|---|---|---|
| Why each one | The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price. | Price Lock Guarantee ensures your monthly rate never increases even as your dose escalates, plus access to 600+ board-certified doctors. |
| Our Score | 7.8/10 | 5.7/10 |
| Headline Price | from $212/mo | from $299/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it | Users who want a monthly price that stays locked as their dose increases, and who can live with a policy that refunds nothing once medication ships |
| Watch out for | The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03) | FDA warning letter 714755, issued September 9, 2025 to MyStart Health LLC, found the claims about compounded semaglutide on mystarthealth.com false or misleading under sections 502(a) and 502(bb) of the Food, Drug, and Cosmetic Act. It concerns marketing, not an allegation that the medication was unsafe, and no public close-out letter had been posted as of September 4, 2026 |
| Ranking | #12 | #43 |
| Get started | Visit Enhance MD | Visit MyStart Health |
Pros & Cons Compared
Enhance MD
Pros
- +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
- +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
- +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
- +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding
Cons
- −The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
- −Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
- −Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
- −Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)
MyStart Health
Pros
- +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates, a genuine differentiator
- +All-inclusive $299 a month on the homepage FAQ, covering physician evaluations, unlimited clinician access, medication, blood work and shipping, with no membership fee on top
- +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
- +You are not charged if you do not qualify: the homepage FAQ promises a full refund within 24 to 48 hours if a doctor finds you ineligible, and a free video appointment in that case
Cons
- −FDA warning letter 714755, issued September 9, 2025 to MyStart Health LLC, found the claims about compounded semaglutide on mystarthealth.com false or misleading under sections 502(a) and 502(bb) of the Food, Drug, and Cosmetic Act. It concerns marketing, not an allegation that the medication was unsafe, and no public close-out letter had been posted as of September 4, 2026
- −Cash-pay only, no insurance accepted, and the only payment method the site names is a credit card. If your plan covers GLP-1s, price that route first
- −Nothing is refundable once your medication ships, including if you are dissatisfied or hit side effects, and returned medication is never accepted (refund policy effective December 1, 2025)
- −Compounded medications only, no brand-name GLP-1 option on the menu
Our Verdict
Enhance MD edges out MyStart Health with a score of 7.8/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; MyStart Health is from $299/mo.
Cheapest complete recurring price in our index
Eden Health GLP-1
$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both
Both Enhance MD and MyStart Health start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.
Read Full Reviews
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Our pick of these two: Enhance MD · 7.8/10