Enhance MD vs MyStart Health: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Enhance MD beats MyStart Health overall, scoring 7.8/10 vs 7.7/10. Enhance MD is more affordable at $212/mo vs $299/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose MyStart Health for users who value a money-back weight-loss guarantee and price.
A side-by-side comparison of Enhance MD and MyStart Health covering pricing, scores, medication types, insurance, and more to help you decide.
Enhance MD
#18 of 48Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.
Visit Enhance MDMyStart Health
#23 of 48GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.
Visit MyStart Health| Feature | Enhance MD | MyStart Health |
|---|---|---|
| Our Score | 7.8/10 | 7.7/10 |
| Starting Price | $212/mo | $299/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | No | No |
| Best For | Budget-conscious users interested in combination therapies | Users who value a money-back weight-loss guarantee and price-lock protection |
| Ranking | #18 | #23 |
Pros & Cons Compared
Enhance MD
Pros
- +$115/mo starting price with access to both brand-name and compounded — rare at this price point
- +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
- +Quick asynchronous consultations — most patients approved within 24 hours without video calls
- +Flexible dosing: can start at lower doses than standard protocols for sensitive patients
Cons
- −Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
- −No insurance billing and limited customer support hours (business days only, no weekends)
MyStart Health
Pros
- +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates — a genuine differentiator
- +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
- +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
- +HSA/FSA eligible — can use pre-tax health savings to pay for treatment
Cons
- −Cash-pay only — no insurance accepted, which limits options for patients with GLP-1 coverage
- −Only available in select states — not all 50, and the exact state list isn't published
- −Compounded medications only — no brand-name GLP-1 options available
Our Verdict
Enhance MD edges out MyStart Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, Enhance MD starts at $212/mo compared to MyStart Health's $299/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose MyStart Health if you want: users who value a money-back weight-loss guarantee and price-lock protection.
Still undecided? Editor's #1 Overall Pick
Eden Health GLP-1
$249/mo · 8.9/10 · Both
If neither Enhance MD nor MyStart Health feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.
Read Full Reviews
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