Enhance MD vs MangoRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Enhance MD beats MangoRx overall, scoring 7.8/10 vs 7.5/10. Enhance MD is more affordable at $212/mo vs $299/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose MangoRx for users who want a multi-service telehealth platform covering .

A side-by-side comparison of Enhance MD and MangoRx covering pricing, scores, medication types, insurance, and more to help you decide.

Higher Rated

Enhance MD

#18 of 48

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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MangoRx

#27 of 48

7.5/10

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

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Feature	Enhance MD	MangoRx
Our Score	7.8/10	7.5/10
Starting Price	$212/mo	$299/mo
Medication Type	Both	Compounded
Insurance Accepted	No	No
Best For	Budget-conscious users interested in combination therapies	Users who want a multi-service telehealth platform covering weight loss and men's health
Ranking	#18	#27

Pros & Cons Compared

Enhance MD

Pros

+$115/mo starting price with access to both brand-name and compounded — rare at this price point
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations — most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
−No insurance billing and limited customer support hours (business days only, no weekends)

MangoRx

Pros

+Oral dissolving tablets exclusively — zero injections for any GLP-1 option
+Publicly traded on NASDAQ (MGRX) — SEC-required financial transparency that private competitors can't match
+Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
+Free 100% online consultation with no video call required

Cons

−$299/mo for oral semaglutide is 2-3x the cost of injectable alternatives at $99-149/mo
−Early-stage public company with limited revenue — stock performance reflects financial uncertainty
−Only oral tablet format available — no injectable options if you want higher bioavailability

Our Verdict

Enhance MD edges out MangoRx with a score of 7.8/10 vs 7.5/10. If budget is your priority, Enhance MD starts at $212/mo compared to MangoRx's $299/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose MangoRx if you want: users who want a multi-service telehealth platform covering weight loss and men's health.

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither Enhance MD nor MangoRx feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review