HealthRX vs Yucca Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

53 providers verified independently·Independent research·How we rank →

Visit Yucca Health - our pick of these two→or find your match

Yucca Health beats HealthRX overall, scoring 7.7/10 vs 5.2/10. HealthRX is more affordable at $99/mo vs $146/mo. Choose HealthRX for cash-pay patients who want low flat-dose compounded glp-1 pr. Choose Yucca Health for people who'll commit to a 6-month plan for $146/mo, want nam.

A side-by-side look at HealthRX and Yucca Health to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

HealthRX

#50 of 53

5.2/10

HealthRX is a cash-pay telehealth platform for compounded injectable semaglutide and tirzepatide. Its July 2026 landing page lists semaglutide at $133/mo on a 3-month plan or $99/mo on a 12-month plan, plus tirzepatide at $209/mo or $179/mo. Prices stay flat across doses and include clinician review, dose adjustments, and overnight shipping. MD Integrations supplies the clinician network, while the dispensing 503A pharmacy remains unnamed on the public site.

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Higher Rated

Yucca Health

#17 of 53

7.7/10

Online weight-loss program by Yucca Health, Inc. (Beverly Hills, CA). Two named board-certified doctors, Dr. Michael Wasef MD and Dr. Andrew Sakla DO, handle prescribing. 20,000+ patients, 4.6 stars across 1,065 verified Trustpilot reviews. Starts at $146/mo for compounded semaglutide (custom-made version, not the FDA-approved brand) on the 6-month plan. Buy-now-pay-later via Klarna, Affirm, or Afterpay spreads the upfront commitment.

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Feature	HealthRX	Yucca Health
Our Score	5.2/10	7.7/10
Starting Price	$99/mo	$146/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Cash-pay patients who want low flat-dose compounded GLP-1 pricing, all-50-state access, fast shipping, and self-service cancellation	People who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (Klarna/Affirm/Afterpay)
Ranking	#50	#17
Get started	Visit HealthRX	Visit Yucca Health

Pros & Cons Compared

HealthRX

Pros

+$99/mo compounded semaglutide on the 12-month plan, with a $133/mo 3-month option
+Flat pricing across doses, clinician review, dose adjustments, and overnight shipping included
+Licensed clinicians in all 50 states through MD Integrations, with most files reviewed within about 24 hours
+LegitScript certificate 50087439 links to the issuer's verification checker
+Single-click account cancellation and refunds for unshipped doses
+Published HIPAA notice, telehealth consent, safety information, and emergency instructions

Cons

−The dispensing 503A pharmacy is described by type while its name and license remain absent from the public site
−Legal entity, headquarters, executive team, and medical director remain undisclosed
−The tirzepatide product page advertises $149/mo while the current affiliate landing and FAQ say $179/mo, so confirm the checkout rate
−The 4.8/5 from 12,000+ members block uses illustrative composites rather than an independent review platform
−Cash-pay only, with no insurance billing or prior-authorization support
−Compounded medications sit outside FDA premarket approval as finished products

Yucca Health

Pros

+Two named board-certified doctors (Dr. Michael Wasef MD and Dr. Andrew Sakla DO), most compounded GLP-1 providers don't publicly name their prescribers.
+4.6 stars across 1,065 verified Trustpilot reviews, 84% give 5 stars. Top complimented theme: customer service.
+Cheap if you commit: $146/mo for compounded semaglutide on the 6-month plan.
+Buy-now-pay-later through Klarna, Affirm, and Afterpay, unusual flexibility in this category, useful for spreading the 6-month upfront cost.
+24-hour async approval, no live video visit required. Faster onboarding than competitors that need a scheduled call.
+UPS 2-Day Air shipping included. Onboarding call from a real human (multiple Trustpilot reviewers name 'Hazel' and 'Johann' from the team).
+Replies to 100% of negative Trustpilot reviews, usually within 48 hours.

Cons

−Compounded-only, no FDA-approved Wegovy, Zepbound, Ozempic, or Mounjaro.
−The $146/mo price requires a 6-month upfront commitment (month-to-month is meaningfully more expensive). The Klarna/Affirm/Afterpay financing exists to spread exactly that upfront cost.
−No live tele-visit option, only async review. Faster, but less depth if you have a complex health history and want a provider you can talk to.
−Pharmacy partner not named publicly. Yucca says 'U.S. licensed pharmacies' but doesn't disclose which one.
−Founders and detailed company history not on the site.
−Refund policy is mentioned but not detailed publicly, get the cancellation terms in writing before paying for the 6-month plan.

Our Verdict

Yucca Health edges out HealthRX with a score of 7.7/10 vs 5.2/10. If budget is your priority, HealthRX starts at $99/mo compared to Yucca Health's $146/mo. Choose HealthRX if you want: cash-pay patients who want low flat-dose compounded glp-1 pricing, all-50-state access, fast shipping, and self-service cancellation. Choose Yucca Health if you want: people who'll commit to a 6-month plan for $146/mo, want named doctors on record, and like buy-now-pay-later flexibility (klarna/affirm/afterpay).

Still undecided? Editor's Featured Pick

TrimRx

$149/mo · 7.8/10 · Compounded

If neither HealthRX nor Yucca Health feels like the right fit, our featured pick across all 53 GLP-1 telehealth providers is TrimRx. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $149/mo that stays the same at every dose.

Visit TrimRx→Read our full TrimRx review