Comparison · updated October 16, 2026

HealthRX vs Sesame Care: HealthRX for compounded medication, Sesame Care for brand-name medication

HealthRX and Sesame Care differ in what you pay, which medicines they list and their insurance terms. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

HealthRX and Sesame Care pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money

Which should you choose, HealthRX or Sesame Care?

Short answer: Choose HealthRX if you want a compounded medicine and accept that it is not FDA-approved. Choose Sesame Care if you want brand-name medicine rather than a compounded version.

Choose HealthRX if

  • you want a compounded medicine and accept that it is not FDA-approved

Choose Sesame Care if

  • you want brand-name medicine rather than a compounded version
  • you want a pill or another option without needles
  • you want to use insurance

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

HealthRX vs Sesame Care side by side

HealthRX and Sesame Care compared fact by fact
HealthRXSesame Care
Price$99/mo equivalent$1,188 upfront for 12 months; applicable taxes may add to the bill$99/moProgram fee + medication; confirm monthly vs 28-day billing
MedicineCompounded onlyBrand-name only
Needle-free optionNot listedYes, a pill or other oral form
InsuranceNo insurance listedAccepts insurance
ConsultationIncludedVisits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscription
ShippingIncluded (free overnight shipping)Not published
Where it shipsBothAll 50 states
TrustpilotNot tracked4.6 / 5 across 4,533 reviews
BBB ratingNot trackedA+
Our score7.3/10 Fair6.7/10 Fair
Assessment limitsChecked Jul 18, 2026; few independent reviews yet.Checked Oct 16, 2026; a rating claim didn't match Trustpilot.

What HealthRX and Sesame Care plans cost

HealthRX

Published prepaid schedules and separate monthly Subscribe and Save offers, with clinician review and shipping advertised as included. Compare the first charge, renewal bill and refund conditions.

  • Compounded Semaglutide, Monthly Plan$190$190 billed for the first month on its pricing page, renewing at $165. The same page also lists a Subscribe and Save monthly option at $149 for the first month, then $165 per month.
  • Compounded Semaglutide, 3-Month Plan$133$399 billed for 3 months, $133/mo, renewing at $374 on its pricing page. Flat across doses with clinician review, dose adjustments and overnight shipping included.
  • Compounded Semaglutide, 6-Month Plan$119$714 billed for 6 months, $119/mo, renewing at $689 on its pricing page. Cheaper per month than the 3-month plan for half the commitment of the annual one.
All 8 HealthRX plans
How HealthRX bills

12-month semaglutide rate, $1,188 paid up front. A separate Subscribe and Save offer is $149 for the first month, then $165; the pricing table also lists a $190 first-month option

We checked HealthRX's prices on September 3, 2026.

Sesame Care

Provider choice, ongoing video care and medication prior-authorization help, with a separately priced brand-name GLP-1 menu and $59/mo advertised care on an annual commitment.

  • Success by Sesame (12-month plan)$59The $59/mo headline rate. The program page footnote reads "Based on a 12-month Success by Sesame commitment". Bundles provider visits, unlimited messaging and provider choice. Medication is separate.
  • Success by Sesame (6-month plan)$69Billed once every 6 months. The FAQ publishes this as a saving of $180 every 6 months against the $99 monthly rate, which works out near $69/mo. Medication is separate.
  • Success by Sesame (3-month plan)$79Billed once every 3 months. The FAQ publishes this as a saving of $60 every 3 months against the $99 monthly rate, which works out near $79/mo. Medication is separate.
All 9 Sesame Care plans
  • Success by Sesame (month-to-month)$99$99 program fee with no commitment; medication is separate. One program FAQ says billed every month, while another says every 28 days. Confirm the billing interval, your next payment date and how many charges you will pay in a year.
  • Single Consultation (pay-per-visit)$34One-off telehealth visit, no subscription required. The homepage says visits start at $34 and lists some services from $36.
  • Wegovy Pen (brand-name cash)$199Medication only: $199/month for the first two consecutive months at 0.25 or 0.5 mg for eligible new self-pay patients through December 31, 2026, then $349 for listed 0.25–2.4 mg doses. Care fees are separate
  • Wegovy Pill (oral semaglutide)$149Sesame lists $149/mo at 1.5 or 4 mg and $299 at 9 or 25 mg. Medication only; confirm current offer eligibility and add the separate care fee
  • Zepbound KwikPen (brand-name cash)$299The detailed menu lists $299 at 2.5 mg, $398 at 5 mg, $499 at 7.5 mg and $698 at 10–15 mg. A separate vial teaser also says from $299. Confirm the prescribed format and applicable manufacturer offer; care fees are separate
  • Foundayo (orforglipron oral)$149Medication only. Through December 31, 2026, Sesame's offer FAQ lists $149 at 0.8/2.5 mg, $199 at 5.5 mg and $299 at 9 mg. At 14.5/17.2 mg it lists $349, or $299 with Journey Program terms and refills within 45 days. The medication card shows higher non-promotional figures at some doses; confirm the applicable offer and add care fees
How Sesame Care bills

Program fee only. Medication is extra, so confirm the full bill. The program page says monthly in one FAQ and every 28 days in another. Confirm the billing interval and combined bill before paying.

We checked Sesame Care's prices on October 9, 2026.

What to watch for with HealthRX and Sesame Care

HealthRX

  • The dispensing 503A pharmacy is described by type while its name and license remain absent from the public site
  • Legal entity, headquarters, executive team, and medical director remain undisclosed
HealthRX's strengths, cautions and terms

Strengths

  • $99/mo compounded semaglutide on the 12-month plan, with a $133/mo 3-month option
  • Flat pricing across doses, clinician review, dose adjustments, and overnight shipping included
  • Independent US-licensed clinicians in all 50 states, with the homepage saying a board-certified physician reviews your file within 24 hours
  • Full refund if a provider does not approve you, stated on the homepage, the pricing page and the terms
  • Displays certificate 50087439 with a LegitScript checker link; current issuer confirmation was not resolved in the October 8 check
  • Publishes an email cancellation route and refund eligibility for unshipped doses, subject to the processing and dispensing conditions
  • Published HIPAA notice, telehealth consent, safety information, and emergency instructions

More to watch for

  • The $99/mo semaglutide headline requires $1,188 up front. The separate Subscribe and Save offer is $149 first month, then $165; the $190 table option is not the only monthly offer
  • The historical 4.8/5 from 12,000+ members display used illustrative composite stories, not independent review evidence; that block was not reproduced in the October 8 check
  • Cash-pay only, with no insurance billing or prior-authorization support
  • Compounded medications sit outside FDA premarket approval as finished products
Medicines listed
  • Semaglutide (compounded weekly injection)
  • Tirzepatide (compounded weekly injection)
Insurance
No insurance support listed
Consultation
Included
Shipping
Included (free overnight shipping)
Prescribers
Independent US-licensed clinicians licensed in the patient's state, described on the homepage as board-certified physicians. A clinician network is not named on the site's about, how it works, FAQ or terms pages (rendered check 2026-09-03)
Lab work
Not disclosed
States
All 50 states
Cancellation
The refund policy and FAQ direct cancellation by email. They describe refunds for unshipped doses, subject to processing and dispensing conditions; prescription products are nonreturnable once dispensed and sales are final after shipment. If a provider declines to prescribe after payment, the terms promise a full refund of the related charge, processed manually by support after the clinical decline is recorded. Sources checked October 8, 2026.

Sesame Care

  • Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
  • The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes. For the $99 no-commitment plan, one FAQ says monthly and another says every 28 days. Confirm the interval and number of charges before budgeting for a year.
Sesame Care's strengths, cautions and terms

Strengths

  • Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
  • Published medication-only offers include eligible Wegovy pen starter doses at $199 for two months, then $349; the Wegovy pill and Zepbound KwikPen have dose-specific prices
  • Listed oral brands include Wegovy and Foundayo, with medication starting at $149 for eligible doses; the care fee is separate
  • Provider choice, ongoing video visits, messaging and app tools for weight, dose and side-effect tracking are described in the program

More to watch for

  • Sesame says compounded semaglutide is not currently available. Its published GLP-1 menu is brand-name; medication is billed on top of the program or visit fee.
  • Providers can set higher fees than the advertised program rate. Confirm the selected clinician's price and support arrangements before enrolling
Medicines listed
  • Wegovy (brand-name injection pen)
  • Wegovy (brand-name oral pill)
  • Ozempic (brand-name injection)
  • Zepbound (brand-name KwikPen/vial)
  • Mounjaro (brand-name injection)
  • Rybelsus (brand-name oral)
  • Foundayo (brand-name orforglipron oral, FDA-approved April 2026)
Insurance
Lists insurance support. Confirm coverage for your plan.
Consultation
Visits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscription (verified 2026-09-03)
Shipping
Not published. A shipping cost is not shown on the site's weight loss program, medication or FAQ pages (rendered check 2026-09-03). Prescriptions are picked up at a local pharmacy or sent by home delivery, so any delivery charge comes from the pharmacy
States
All
Cancellation
You can self-cancel Success by Sesame at any time, and cancellation must happen before the next billing cycle starts to avoid the next charge. A full refund applies only if you cancel at least 3 hours before the initial visit, no refund is issued for the first month once that visit has happened, and fees for previous months are not refundable (verified 2026-09-03)

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

HealthRX vs Sesame Care: common questions

Is HealthRX or Sesame Care cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • HealthRX$99/mo equivalent$1,188 upfront for 12 months; applicable taxes may add to the bill
  • Sesame Care$99/moprogram fee + medication; confirm monthly vs 28-day billing

Which is better, HealthRX or Sesame Care?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

HealthRX lists compounded medication only, and Sesame Care lists brand-name medication only. Sesame Care lists insurance support, and HealthRX does not.

Do HealthRX and Sesame Care offer brand-name medication?

HealthRX lists compounded medication only, and Sesame Care lists brand-name medication only.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do HealthRX and Sesame Care take insurance?

Sesame Care lists insurance support, and HealthRX does not.

Confirm coverage for your exact plan and prescription before you pay.

Where these facts come from

HealthRX:prices checked September 3, 2026.Read our HealthRX review

Sesame Care:prices checked October 9, 2026, score evidence assessed October 16, 2026.Read our Sesame Care review

We score on a published methodology, and partnership never changes a score or a fact here.

What should you compare next?

Before you sign up, read our trust check: is Sesame Care legit.

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