Enhance MD vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Sesame Care beats Enhance MD overall, scoring 7.9/10 vs 7.8/10. Sesame Care is more affordable at $99/mo vs $212/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.

A side-by-side comparison of Enhance MD and Sesame Care covering pricing, scores, medication types, insurance, and more to help you decide.

Enhance MD

#18 of 48

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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Higher Rated

Sesame Care

#10 of 48

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications — including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.

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Feature	Enhance MD	Sesame Care
Our Score	7.8/10	7.9/10
Starting Price	$212/mo	$99/mo
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Budget-conscious users interested in combination therapies	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Ranking	#18	#10

Pros & Cons Compared

Enhance MD

Pros

+$115/mo starting price with access to both brand-name and compounded — rare at this price point
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations — most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
−No insurance billing and limited customer support hours (business days only, no weekends)

Sesame Care

Pros

+Success by Sesame program launched 2026 — $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
+Brand-name cash pricing is competitive — Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Membership model adds complexity — two distinct products (pay-per-visit vs Success membership) can be confusing
−Success by Sesame requires a 3-month minimum commitment to hit the $59/mo rate
−Compounded meds are de-emphasized on the current marketing — focus has shifted to FDA-approved brand-name paths
−Less hand-holding than dedicated subscription platforms like Willow or Eden Health

Our Verdict

Sesame Care edges out Enhance MD with a score of 7.9/10 vs 7.8/10. If budget is your priority, Sesame Care starts at $99/mo compared to Enhance MD's $212/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither Enhance MD nor Sesame Care feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review