Enhance MD vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent research·How we rank →

Sesame Care beats Enhance MD overall, scoring 7.9/10 vs 7.8/10. Sesame Care is more affordable at $99/mo vs $212/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.

A side-by-side look at Enhance MD and Sesame Care to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Enhance MD

#16 of 52

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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Higher Rated

Sesame Care

#7 of 52

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications, including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.

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Feature	Enhance MD	Sesame Care
Our Score	7.8/10	7.9/10
Starting Price	$212/mo	$99/mo
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Budget-conscious users interested in combination therapies	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Ranking	#16	#7
Get started	Visit Enhance MD	Visit Sesame Care

Pros & Cons Compared

Enhance MD

Pros

+GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations, most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
−No insurance billing, and customer support runs business days only, no weekends

Sesame Care

Pros

+Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
+Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
−The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
−Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
−A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Sesame Care edges out Enhance MD with a score of 7.9/10 vs 7.8/10. If budget is your priority, Sesame Care starts at $99/mo compared to Enhance MD's $212/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither Enhance MD nor Sesame Care feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Visit Yucca Health→Read our full Yucca Health review