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MEDVi vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 5.7/10. Full reasoning, pricing and the cases where the other one wins are below.

Sesame Care beats MEDVi overall, scoring 7.9/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: MEDVi is $179 first month, then $299/mo; Sesame Care is published $99/mo; total not verified. Choose MEDVi for users who want both oral and injectable compounded options in one telehealth program. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

A side-by-side look at MEDVi and Sesame Care to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

MEDVi

#46 of 54
5.7/10

MEDVi offers oral and injectable compounded GLP-1 care. Semaglutide is $179 for month one and $299 for refills. Trustpilot is 4.4/5 across roughly 11,000 reviews, while BBB is F/not accredited. FDA warning letter #721455 concerns misleading labeling and marketing, not an allegation that the medication was unsafe.

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Higher Rated

Sesame Care

#5 of 54
7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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FeatureMEDViSesame Care
Why each oneOral and injectable compounded formats in one program, with micro-dosing options and a path to FDA-approved brand medication.The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.
Our Score5.7/107.9/10
Headline Price$179 first month, then $299/mopublished $99/mo; total not verified
Medication TypeBothBoth
Insurance AcceptedNoYes
Best ForUsers who want both oral and injectable compounded options in one telehealth programUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Watch out forFDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medicationTwo distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
Ranking#46#5
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Pros & Cons Compared

MEDVi

Pros

  • +One of the few compounded providers offering both oral tablets and injectable semaglutide
  • +Micro-dosing options available, can start at sub-standard doses for patients concerned about side effects
  • +Sleek onboarding experience with clear progress tracking through their patient portal
  • +$179 covers the first month of compounded semaglutide on the current Katalys landing, including clinician review, medication and shipping

Cons

  • FDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medication
  • Its third-party records conflict: 4.4/5 across roughly 11,000 Trustpilot reviews, but an F and no accreditation at the BBB
  • The $179 semaglutide price is introductory; the current Katalys landing says refills are $299/mo, making the first-year total $3,468 rather than $2,148
  • Brand-name Wegovy and Zepbound paths add a $99 membership plus the medication cost, which the current landing does not publish; availability can change
  • No insurance accepted, and oral compounded semaglutide has less clinical data than injectable forms

Sesame Care

Pros

  • +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

  • Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
  • The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
  • Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Sesame Care edges out MEDVi with a score of 7.9/10 vs 5.7/10. Published pricing is not a like-for-like monthly comparison: MEDVi is $179 first month, then $299/mo; Sesame Care is published $99/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs.

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