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GuideComparisonsJune 22, 202610 min read

Oral GLP-1 Pills for Weight Loss (2026): Foundayo, Oral Semaglutide (Wegovy) & All Options

As of 2026, two FDA-approved oral GLP-1 pills exist for weight loss: Foundayo (orforglipron, 12.4% weight loss, $149/mo self-pay via LillyDirect, no fasting needed, approved April 1) and the Wegovy pill (semaglutide 25mg, 16.6% weight loss, $1,349/mo list price, requires 30-min fast before dosing, approved December 2025). Rybelsus is oral semaglutide but approved for type 2 diabetes only, not weight loss.

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$146/mo·Compounded

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$149/mo·Brand & Compounded

TrimRx

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$149/mo·Compounded

SkinnyRx

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$199/mo·Compounded

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