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Editorial photograph illustrating a comparison of Zepbound and Mounjaro tirzepatide medications
AnalysisComparisonsApril 22, 202612 min read

Zepbound vs Mounjaro (April 2026): Same Drug, Different Labels, Which Is Right for You?

Verified July 2026: Zepbound and Mounjaro are the exact same drug (tirzepatide) at the same doses. Mounjaro was FDA-approved May 2022 for Type 2 diabetes. Zepbound was FDA-approved November 2023 for chronic weight management and December 2024 for obstructive sleep apnea. List price is ~$1,087/mo for both; with commercial insurance + savings cards both drop to $25/mo (max $1,950/yr). The real differences: which one your insurance covers, what the FDA label allows, and Zepbound's LillyDirect self-pay vials at $299-$449/mo, a program Mounjaro does not offer.

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