Cheapest Tirzepatide Online in 2026
The cheapest tirzepatide online in 2026 starts at $99/mo all-in from Sesame Care. We compared 32 telehealth providers that offer tirzepatide (the active ingredient in Zepbound and Mounjaro) and ranked them by total monthly cost — including medication, consultations, shipping, and any membership fees. No hidden costs.
Tirzepatide is a dual GIP/GLP-1 receptor agonist that produces up to 22.5% body weight loss in clinical trials — the highest of any FDA-approved weight loss medication. Brand-name Zepbound costs $1,086/mo list price, but compounded and telehealth options start much lower.
Tirzepatide Providers Ranked by Total All-In Cost
Prices include medication, consultations, shipping, and any membership fees. Sorted cheapest first.
| # | Provider | All-In Price | Score | Type | Insurance | |
|---|---|---|---|---|---|---|
| 1 | Sesame Care #10 overall | $99/mo | 7.9/10 | Both | Yes | Visit |
| 2 | Ivim Health #11 overall | $150/mo | 7.9/10 | Both | No | Visit |
| 3 | PeterMD #28 overall | $165/mo | 7.3/10 | Compounded | No | Visit |
| 4 | Mochi Health #18 overall | $178/mo | 7.7/10 | Compounded | No | Visit |
| 5 | Henry Meds #6 overall | $199/mo | 8.4/10 | Both | No | Visit |
| 6 | TMates #15 overall | $199/mo | 7.8/10 | Compounded | Yes | Visit |
| 7 | SynergyRx #22 overall | $199/mo | 7.6/10 | Both | No | Visit |
| 8 | Care Bare Rx #24 overall | $199/mo | 7.4/10 | Both | No | Visit |
| 9 | Breeze Meds #29 overall | $199/mo | 7.3/10 | Compounded | No | Visit |
| 10 | Calibrate #19 overall | $199/mo | 7.7/10 | Both | Yes | Visit |
| 11 | Shed #16 overall | $199/mo | 7.8/10 | Compounded | No | Visit |
| 12 | Enhance MD #17 overall | $212/mo | 7.8/10 | Both | No | Visit |
| 13 | Elevate Health #34 overall | $233/mo | 7.2/10 | Compounded | No | Visit |
| 14 | Sprout Health #2 overall | $249/mo | 8.8/10 | Both | No | Visit |
| 15 | Fridays #3 overall | $249/mo | 8.7/10 | Both | Yes | Visit |
| 16 | Eden Health GLP-1 #1 overall | $249/mo | 8.9/10 | Both | No | Visit |
| 17 | MyStart Health #20 overall | $249/mo | 7.7/10 | Both | No | Visit |
| 18 | Found #30 overall | $264/mo | 7.3/10 | Both | Yes | Visit |
| 19 | WeightWatchers (Sequence) #25 overall | $273/mo | 7.4/10 | Both | Yes | Visit |
| 20 | Zealthy #35 overall | $286/mo | 7.2/10 | Both | No | Visit |
| 21 | Willow #8 overall | $299/mo | 8.2/10 | Both | No | Visit |
| 22 | Fella Health #26 overall | $299/mo | 7.4/10 | Compounded | No | Visit |
| 23 | Embody #31 overall | $299/mo | 7.3/10 | Compounded | No | Visit |
| 24 | MangoRx #23 overall | $299/mo | 7.5/10 | Compounded | No | Visit |
| 25 | Noom Med #27 overall | $299/mo | 7.4/10 | Both | Yes | Visit |
| 26 | Maximus #38 overall | $300/mo | 7.1/10 | Compounded | No | Visit |
| 27 | Hone Health #32 overall | $309/mo | 7.3/10 | Compounded | No | Visit |
| 28 | GoodRx Care #40 overall | $318/mo | 6.2/10 | Brand | Yes | Visit |
| 29 | bmiMD #9 overall | $319/mo | 8/10 | Both | No | Visit |
| 30 | AgelessRx #39 overall | $340/mo | 7/10 | Both | No | Visit |
| 31 | Ro #36 overall | $344/mo | 7.2/10 | Brand | Yes | Visit |
| 32 | Lemonaid Health #37 overall | $348/mo | 7.2/10 | Compounded | No | Visit |
Why Choose Tirzepatide Over Semaglutide?
Tirzepatide (Zepbound/Mounjaro) is a dual GIP + GLP-1 receptor agonist — it activates two hormonal pathways instead of one. In the head-to-head SURMOUNT-5 trial, tirzepatide produced 20.2% weight loss vs semaglutide's 13.7% (p<0.001). The tradeoff: tirzepatide programs tend to cost $50-150/mo more than semaglutide-only options.
Brand-Name Zepbound vs Compounded Tirzepatide
| Factor | Brand-Name Zepbound | Compounded Tirzepatide |
|---|---|---|
| List price | $1,086/mo | $149-$399/mo |
| Via LillyDirect | $299-$449/mo | N/A |
| FDA approved | Yes | No (pharmacy-compounded) |
| Insurance eligible | Often | Rarely |
| Regulatory risk | None | FDA enforcement ongoing |
Read our full guide: Brand-Name vs Compounded GLP-1 Medications