Independent provider comparison

Updated September 26, 2026

Calibrate vs Trimi Health: Which GLP-1 provider is better?

A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

The decision

Which should you choose, Calibrate or Trimi Health?

Short answer: Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Trimi Health is $175/mo month-to-month. Compare the exact medication, renewal bill and cancellation terms before choosing.

Consider Calibrate if

Insured users who want a clinician-led metabolic health program on a three-month commitment, with brand-name GLP-1s only and medication plus labs billed to their own plan.

Consider Trimi Health if

Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.

Scores follow our published methodology. Partnership status does not change the score or the factual comparison.

Cost

First charge, renewal and commitment

Treatment

Medication, form and approval status

Care

Clinical review and ongoing support

Terms

Cancellation and material cautions

Calibrate logo

Calibrate

Last published score
7.7/10

Best for insured users who want a clinician-led metabolic health program on a three-month commitment, with brand-name glp-1s only and medication plus labs billed to their own plan.

View Calibrate terms
Trimi Health logo

Trimi Health

Last published score
4.2/10

Best for cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.

Visit Trimi Health

Side by side

Calibrate vs Trimi Health at a glance

Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.

FeatureCalibrateTrimi Health
Last Published Score7.7/104.2/10
Headline Pricepublished $199/mo; total not verified$175/mo month-to-month
Medication TypeBrandCompounded
Insurance AcceptedYesNo
Best ForInsured users who want a clinician-led metabolic health program on a three-month commitment, with brand-name GLP-1s only and medication plus labs billed to their own plan
Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange
Watch out forThe first three months are locked in: the membership terms give no refunds once a month is paid and no waiver of the remaining installments if you stop early, so leaving in month two still costs the full $597
Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality
Get startedView Calibrate termsVisit Trimi Health

How do the plan costs and terms compare?

Compare the full bill, not just the advertised monthly number. These are published terms, not a personal prescription quote. We may earn a commission from marked partner links; other providers appear here for comparison. Scores use our last published assessment; source dates below distinguish price checks from that assessment. How our links work.

Calibrate: price and commitment

program fee only; medication billed separately, all-in total not verified

See all published plans and prices

Calibrate Program (3-month commit): $199. $199/mo × 3-month minimum = $597 upfront, then month-to-month. Includes physician consultations, coaching, labs, smart scale, and app. Medication billed separately.

Cancellation: Three-month initial term billed as three monthly installments, then month to month, and you can cancel any time after the initial term by email. No early termination fee, but the membership terms give no refunds once a term is paid and no waiver of unpaid installments during the initial term (verified 2026-09-03)

Price source checked August 28, 2026. Confirm current eligibility, medication, term and total before paying.

Calibrate official pricing source

Score evidence last assessed September 3, 2026.

Trimi Health: price and commitment

month-to-month; $99/mo on an annual plan billed yearly

See all published plans and prices

Compounded Semaglutide, Month-to-Month: $175. $175/mo with no commitment. Consult + overnight shipping included. Flat across doses. The lowest-risk way to try Trimi given the no-pro-rating terms.

Compounded Semaglutide, 3-Month Plan: $145. $145/mo on a 3-month plan.

Compounded Semaglutide, 6-Month Plan: $120. $120/mo on a 6-month plan.

Compounded Semaglutide, Annual Plan: $99. $99/mo billed $1,188 once yearly. Cheapest rate, highest risk: payments are final once a prescription is signed, with no pro-rating if you cancel mid-year.

Compounded Tirzepatide, Month-to-Month: $235. $235/mo with no commitment. Flat across doses.

Compounded Tirzepatide, 3-Month Plan: $199. $199/mo billed $597 every 3 months. A commitment for its stated term, per the pricing page.

Compounded Tirzepatide, 6-Month Plan: $175. $175/mo billed $1,050 every 6 months. A commitment for its stated term, per the pricing page.

Compounded Tirzepatide, Annual Plan: $125. $125/mo billed $1,500 once yearly. Same no-pro-rating caveat as the semaglutide annual plan.

Cancellation: Full refund any time BEFORE a prescription is signed. After that, payments are final with no pro-rating, and the quarterly, 6-month and annual tiers are commitments for their stated term, though the refund policy says multi-month bundles are reviewed case by case if you want to exit early. A 6-month money-back weight-loss promise is published, and it requires a logged starting weight and a logged six-month weight in the patient portal. Terms include mandatory arbitration and a class action waiver, with a written opt-out available within 30 days of first accepting them

Price source checked September 23, 2026. Confirm current eligibility, medication, term and total before paying.

Trimi Health official pricing source

Compounded medications are not FDA-approved; FDA does not review them for safety, effectiveness or quality before marketing. FDA's explanation of compounded-drug risks.

Trade-offs

Strengths and cautions compared

Calibrate

Pros

  • +2026 pricing rewrite: a $199/mo program fee billed as three monthly installments across the commitment, $597 in total, then month to month; the old $1,649 one-time enrollment fee is gone
  • +Clinicians are US-licensed and board-certified, described on the site's FAQ as nurse practitioners, and Calibrate names its chief medical officer on the medication page
  • +10% weight-loss guarantee that pays back 50% of membership fees, though only after 12 consecutive self-paid months
1 more documented strengths
  • +Nutrition coaching, a personalized smart scale, sleep and exercise support, and full insurance navigation are all inside the $199 fee

Cons

  • −The first three months are locked in: the membership terms give no refunds once a month is paid and no waiver of the remaining installments if you stop early, so leaving in month two still costs the full $597
  • −Both medication and lab tests are billed outside the $199 fee, so your real monthly cost depends on your own insurance plan rather than on the headline price
  • −Brand-name GLP-1s only, with no cash-pay compounded lane, so if your insurance denies coverage there is no cheaper in-house option to fall back on
1 more documented cautions
  • −You wait one to two weeks before a clinician sees you: the published timeline puts signup on day 1, blood work in days 1 to 5, and lab results plus your first clinician visit in days 7 to 14

Trimi Health

Pros

  • +$99/mo compounded semaglutide on the annual plan (billed $1,188 once yearly) is among the cheapest flat recurring rates we track; tirzepatide annual is $125/mo ($1,500 yearly)
  • +Flat pricing across all doses, your monthly price does not rise as your dose titrates up
  • +Consult and overnight shipping included in the plan price, no add-on fees; HSA/FSA accepted, Klarna and Affirm financing available
4 more documented strengths
  • +Two named physicians, Dr. Sean Arora MD (medical director) and Dr. Shannon Arora MD (chief medical officer) of the Arora Health medical group, most compounded-only platforms name no one
  • +Trimi names BelieveRx (formerly VialsRx, according to Trimi) and GreenwichRx as its 503A pharmacy partners; check the dispensing pharmacy on your own prescription label
  • +Available in all 50 states plus DC per trytrimi.com/states
  • +6-month money-back weight-loss promise published (conditions apply, read them before counting on it)

Cons

  • −Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality
  • −Once a prescription is signed, payments are final, no pro-rating, cancelling an annual plan mid-year forfeits the remainder. Full refund is available only BEFORE the prescription is signed
  • −The site names New York City as its base but publishes no street address and no legal entity name, calling itself only 'Trimi Health' with no LLC or Inc suffix on its contact, about, terms or FAQ pages (rendered check 2026-09-03)
5 more documented cautions
  • −Vial-and-syringe format only, no autoinjector pens, no oral option, no brand-name medications
  • −Trimi says it is LegitScript certified on its treatment pages and links to LegitScript's own checker, but that checker page shows no certification record for trytrimi.com (checked 2026-09-03)
  • −The terms carry a mandatory arbitration clause and a class action waiver, with a written opt-out available within 30 days of first accepting them
  • −The site contradicts itself on commitment: the treatment page FAQ says you can cancel any time with no long-term commitments, while the pricing page and refund policy say the quarterly, 6-month and annual tiers are commitments for their stated term and payments are final once a prescription is issued (checked 2026-09-03)
  • −Free overnight shipping only starts counting after clinician review and after the pharmacy compounds the order, so Trimi's own reviews page puts the honest end to end wait at a few days rather than one night (verified 2026-09-03)

Our Verdict

Published pricing is not a like-for-like monthly comparison: Calibrate is published $199/mo; total not verified; Trimi Health is $175/mo month-to-month. Check the medication, renewal bill and cancellation commitment for the plan you would actually choose. The dated assessments below are not a fresh head-to-head score audit.

Keep narrowing the decision

What should you compare next?

Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both Calibrate and Trimi Health start above the cheapest complete recurring program we track. Across all 36 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Calibrate plan details

Headline price: published $199/mo; total not verified

View Calibrate terms

Try Trimi Health

Headline price: $175/mo month-to-month

Visit Trimi Health

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