28-day intro, one-time · confirm the full bill · checked Oct 24
Check price for DudeMedsOn DudeMeds' site · partner link
Comparison · updated October 24, 2026
DudeMeds vs SkinnyRx: DudeMeds for compounded medication only, SkinnyRx for brand-name or compounded options
DudeMeds and SkinnyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.
First month, ask the renewal price · checked Sep 26
Check price for SkinnyRxOn SkinnyRx's site · partner link
These two prices are different kinds of bill, so read the line under each price before you compare them.
DudeMeds and SkinnyRx pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money
Which should you choose, DudeMeds or SkinnyRx?
Short answer: Choose SkinnyRx if you want brand-name medicine as an option. If that doesn't matter to you, compare their plans below.
DudeMeds is best for
New patients who want a short first supply with a visible one-time total and will confirm DudeMeds' payment terms before paying.
Choose SkinnyRx if
- you want brand-name medicine as an option
- you want a pill or another option without needles
The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.
By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
DudeMeds vs SkinnyRx side by side
| DudeMeds | SkinnyRx | |
|---|---|---|
| Price | $99/4 weeksOne-time new-patient intro, 28-day supply; later supplies priced separately; legal terms describe a 3-month commitment | $99First month, ask the renewal price |
| Medicine | Compounded only | Brand-name and compounded |
| Needle-free option | Not listed | Yes, a pill or other oral form |
| Insurance | BothNo insurance listed | |
| Consultation | Not itemized on the current offer pages; review the charges in secure intake before paying | Included |
| Shipping | Not itemized on the current offer pages; review the charges in secure intake before paying | Free (overnight on all orders) |
| Where it ships | Not available in Alabama, Arkansas, California, Kentucky or South Carolina, according to DudeMeds' product pages | 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states |
| Trustpilot | 2.3 / 5 across 11 reviews | 4.8 / 5 across 4,100 reviews |
| BBB rating | D+ (not accredited) | Not tracked |
| Our score | 4/10 Limited | 5/10 Mixed |
| Assessment limits | Checked Oct 16, 2026; few independent reviews yet. | Checked Oct 16, 2026; a rating claim didn't match Trustpilot. |
What DudeMeds and SkinnyRx plans cost
DudeMeds
Each offer is sold as a one-time supply with its full total shown before intake: $99 (semaglutide + B6) or $149 (tirzepatide + B6) for a new patient's first 28 days, if prescribed.
- Compounded Semaglutide + B6 injection, First Month Intro (new patients)$99/4 weeks$99 one-time total for a 28-day supply, if prescribed.
- Compounded Tirzepatide + B6 injection, First Month Intro (new patients)$149/4 weeks$149 one-time total for a 28-day supply, if prescribed.
Not an ongoing monthly price; 8-week supplies are priced separately. Not available in AL, AR, CA, KY or SC.
How DudeMeds bills
New-patient intro, one-time: semaglutide + B6 $99 or tirzepatide + B6 $149 for a 28-day supply, if prescribed. Not an ongoing monthly price; the legal terms describe a three-month commitment, so confirm the full bill.
We checked DudeMeds' prices on October 24, 2026.
SkinnyRx
A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.
- Compounded Semaglutide (injectable)$99Once-weekly injection, quoted at $99 for the first month on its product page. A microdose option is offered.
- Compounded Semaglutide (tablets)$149Oral dissolving tablet, quoted at $149 for the first month. Confirm the exact dispensing directions and later bill; merchant guidance differs on placement.
- Compounded Tirzepatide (injectable)$99Once-weekly tirzepatide injection, a GLP-1 and GIP dual agonist, quoted at $99 for the first month on its product page.
All 4 SkinnyRx plans
- Compounded Tirzepatide (tablets)$199Oral dissolving tablet, quoted at $199 for the first month. Confirm the exact dispensing directions and later bill; this is not an FDA-approved oral tirzepatide product.
How SkinnyRx bills
$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.
We checked SkinnyRx's prices on September 26, 2026.
What to watch for with DudeMeds and SkinnyRx
DudeMeds
- The product pages call each offer a one-time purchase with no automatic renewal, but the payment consent in the legal terms still makes the first three months of medication fees due even if you stop, non-refundable once paid. Get the terms that apply to your order in writing before paying.
- The product pages do not establish scheduled follow-up appointments. If appointments matter to you, confirm their availability, frequency and any extra cost before enrolling; asynchronous review alone does not establish care quality.
DudeMeds' strengths, cautions and terms
Strengths
- Each offer page shows the full one-time total, the supply length and a weekly comparison figure before intake
- Advertised first-supply totals: $99 for 28 days of semaglutide + B6 or $149 for tirzepatide + B6, if prescribed
- Online intake reviewed by a licensed clinician, who decides whether to prescribe and at what dose
More to watch for
- The company names itself DudeMeds LLC, incorporated in Delaware on its terms of sale page and in Florida on its terms and conditions page, both effective January 1, 2024, and its current contact page publishes no address. The pages we read do not name the dispensing pharmacy, so ask which one fills your prescription before ordering.
- The independent review sample is small and not GLP-1-specific. Confirm the full term, total payment, renewal schedule and refund conditions before committing, rather than treating the first month as a trial.
- Medicines listed
- Semaglutide + vitamin B6 (compounded injectable)
- Tirzepatide + vitamin B6 (compounded injectable)
- Insurance
- No insurance support listed
- Consultation
- Not itemized on the current offer pages; review the charges in secure intake before paying
- Shipping
- Not itemized on the current offer pages; review the charges in secure intake before paying
- States
- Not available in Alabama, Arkansas, California, Kentucky or South Carolina, according to DudeMeds' product pages. In other states, availability and clinical eligibility are confirmed during intake.
- Cancellation
- The product pages call each offer a one-time purchase with no automatic renewal, but the legal terms still describe recurring plan billing and say the first three months of medication fees are due even if treatment stops, and are non-refundable once paid. Confirm which terms apply to your order before paying. The terms of sale let you cancel a first order without charge before the prescription is processed, and cover damaged, defective or wrong products.
SkinnyRx
- Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
- SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
SkinnyRx's strengths, cautions and terms
Strengths
- Four product-specific options to discuss with a clinician: semaglutide or tirzepatide, each as an injection or a dissolving tablet
- $99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
- Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
- A public Trustpilot profile provides service feedback to read alongside the FDA record and the written billing terms; those reviews do not establish tablet effectiveness
More to watch for
- Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
- FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
- Medicines listed
- Semaglutide (compounded, injectable)
- Wegovy Pill (brand-name oral semaglutide, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Foundayo Pill (brand-name orforglipron, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Semaglutide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Tirzepatide (compounded, injectable)
- Tirzepatide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Insurance
- No insurance support listed
- Consultation
- Included
- Shipping
- Free (overnight on all orders)
- States
- 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
- Cancellation
- The September 22 terms allow renewal processing up to five days before the next period and require cancellation at least five days before the applicable renewal-processing date. They include non-refundable fees, return-before-refund conditions and possible reversal of promotional discounts. Product FAQs use simpler cancellation/refund wording. Ask support for the exact deadline, refund eligibility and any return requirement in writing before paying; canceling is not a guaranteed refund.
Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.
DudeMeds vs SkinnyRx: common questions
Is DudeMeds or SkinnyRx cheaper?
At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.
- DudeMeds$99/4 weeksone-time new-patient intro, 28-day supply; later supplies priced separately; legal terms describe a 3-month commitment
- SkinnyRx$99first month, ask the renewal price
Which is better, DudeMeds or SkinnyRx?
Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.
DudeMeds lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.
Do DudeMeds and SkinnyRx offer brand-name medication?
DudeMeds lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.
Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.
Do DudeMeds and SkinnyRx take insurance?
Neither DudeMeds nor SkinnyRx lists insurance support.
Where these facts come from
DudeMeds:prices checked October 24, 2026, score evidence assessed October 16, 2026.Read our DudeMeds review
SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review
We score on a published methodology, and partnership never changes a score or a fact here.
What should you compare next?
- Compare Wegovy pill prices and accessUse the dedicated guide for dose-specific costs, required memberships and which providers currently list the FDA-approved pill.
- Compare semaglutide providers and pricesMove from this head-to-head to the broader semaglutide market without confusing compounded products with FDA-approved brands.
- Compare tirzepatide providers and pricesReview provider options, price units and treatment context across the wider tirzepatide market.
Before you sign up, read our trust checks: is DudeMeds legit and is SkinnyRx legit.
DudeMeds reviewSkinnyRx reviewAll comparisonsFind your match